Detailed information NTG0869201

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: LACPH_RS11100
• Genome accession: NZ_CP132482
• Coordinates: 2379540..2381732 (-)
• Length: 730 a.a.
• NCBI ID: WP_306386952.1
• Uniprot ID: -
• Organism: Lacticaseibacillus parahuelsenbergensis strain NCIMB 15471
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2374540..2386732

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LACPH_RS11080 (LACPH_002214)	-	2374948..2375115 (+)	168	WP_155807535.1	hypothetical protein	-
LACPH_RS11085 (LACPH_002215)	-	2375417..2376394 (+)	978	WP_306386949.1	aldo/keto reductase	-
LACPH_RS11090 (LACPH_002216)	-	2376681..2378036 (-)	1356	WP_306386950.1	threonine/serine exporter ThrE family protein	-
LACPH_RS11095 (LACPH_002217)	-	2378149..2379528 (-)	1380	WP_306386951.1	bacteriocin secretion accessory protein	-
LACPH_RS11100 (LACPH_002218)	comA	2379540..2381732 (-)	2193	WP_306386952.1	peptide cleavage/export ABC transporter	Regulator
LACPH_RS14315	-	2382048..2382194 (-)	147	WP_370531180.1	bacteriocin-like peptide, LSEI_2386 family	-
LACPH_RS11105 (LACPH_002219)	-	2382361..2383674 (+)	1314	WP_306386953.1	GHKL domain-containing protein	-
LACPH_RS11110 (LACPH_002220)	-	2383664..2384470 (+)	807	WP_306386954.1	response regulator transcription factor	-
LACPH_RS11115 (LACPH_002221)	-	2384651..2384935 (-)	285	WP_306386955.1	hypothetical protein	-
LACPH_RS11120 (LACPH_002222)	-	2385413..2385571 (-)	159	WP_306386956.1	bacteriocin leader domain-containing protein	-
LACPH_RS11125 (LACPH_002223)	-	2385599..2385796 (-)	198	WP_010492355.1	hypothetical protein	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81557.01 Da
• Isoelectric Point: 7.0115

>NTDB_id=869201 LACPH_RS11100 WP_306386952.1 2379540..2381732(-) (comA) [Lacticaseibacillus parahuelsenbergensis strain NCIMB 15471]
MVQYKLKLGQAKYYKRYYTPQVDERDCGVAALNMLLKFHGSDYSLAHLRQLAKTDQEGTTALGIVRAAQELHFETKAVKA
DMTLFDLDDVSYPILVHVLKRGELLHYYVVFKATKDHILIGDPDPSVAMTWLSKDEFTKEWSGVAIFIAPEPQYQPHKED
KGSLFAFVPLLARQKVIIANIIVAALLITVISIVGSYFLQSIIDTYIPSAMRTTLGMIASGLILAYILQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFATRRTGEIVSRFSDANKIIDALANTIMTLFLDVWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYAKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLSYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRHLTDRSLIDGAIIVNDVSFKYGFGQDILKHVHLEVPANAKYTIVGMSGSGKSTLAKLLVGFYPVETGRGKITFNGAQI
DDVALTTLRQYIEYVPQEPFIFSGSVMENLTLGSRADLTQAQLEDACAVAEIATDIMNLPQMWQTKLTESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERRIVDRLLAMKDRTIIFVAHRLTIAAKTEQIVVMDHGEIVEQGNHAELLAK
QGYYARLVSE

Nucleotide

• Length: 2193 bp

>NTDB_id=869201 LACPH_RS11100 WP_306386952.1 2379540..2381732(-) (comA) [Lacticaseibacillus parahuelsenbergensis strain NCIMB 15471]
ATGGTTCAGTACAAACTAAAACTAGGTCAAGCAAAATACTACAAACGCTATTACACGCCTCAGGTGGATGAGCGTGATTG
CGGCGTTGCGGCGCTTAATATGTTGCTGAAGTTTCATGGGTCCGACTATTCACTCGCACATTTACGGCAACTGGCGAAGA
CTGATCAAGAAGGAACGACGGCGTTAGGCATTGTTCGCGCTGCCCAGGAACTTCATTTTGAAACCAAGGCAGTTAAGGCG
GATATGACGTTGTTTGATTTGGATGATGTTTCATATCCGATCTTGGTGCATGTTTTGAAGCGCGGCGAGCTGTTGCATTA
TTATGTCGTGTTTAAGGCGACGAAGGATCATATCTTAATCGGTGATCCTGACCCTTCAGTCGCGATGACCTGGCTTTCAA
AAGATGAGTTTACCAAGGAGTGGTCGGGGGTCGCTATTTTCATTGCGCCTGAACCGCAATATCAACCGCACAAAGAGGAC
AAAGGCAGTTTGTTTGCCTTCGTGCCGTTGCTCGCGCGGCAAAAAGTGATTATTGCCAATATTATTGTTGCGGCTTTGTT
GATCACGGTGATTAGCATTGTTGGGTCGTATTTTCTGCAATCGATCATTGATACCTACATTCCAAGTGCTATGCGGACAA
CTTTAGGGATGATCGCCAGTGGGCTGATTCTCGCCTACATTCTCCAATCCGTTTTGACGTATGGCCAGAATTTCTTGATG
GCGGTTTTAGGCCAGCGATTGTCGATTGACGTTATTTTAGGTTACGTTCGGCATCTGTATGAATTACCCATGTCCTTTTT
TGCAACGCGCCGGACAGGGGAGATTGTGTCGCGGTTTTCGGACGCCAATAAAATTATTGATGCCTTGGCGAATACGATTA
TGACTCTGTTTCTTGACGTTTGGATCGTGCTTATTTTAGGCATTGTTTTGGGCATTCAAAATACTACATTGTTCCTGGTG
TCCTTAATTGCGGTGCCTTGTTACTTGGTGATTGTTTTCGCGTTTCAACGTCCTTTCAATCGGCTGAATCAAGAGACAAT
GGAAAGCAATGCCATTTTGAGCTCATCGATTATTGAGGATCTGAACGGTATTGAGACCATTAAGTCGCTGACAGGCGAAA
AAGTCAGTTATGAACGGGTTGACCGTGAATTCGTTACGTATTTAAAAAAGTCATTCAATTACGCGAAAGCTGACCAACTT
CAACAAGCCATCAAGGGGTTGCTGAAACTCGTCTTGAATGTGGTGGTGTTGTGGATTGGGGCGAGTCTGGTGATGGCTAA
CAAGATGAGCTTGGGGCAGATGCTGACGTTCAATGCCTTGCTGTCATACTTCACCAATCCGTTAGAAAGCATCATTAACT
TGCAACCAAAATTGCAAATGGCTAAGGTGGCGAATAATCGGCTGAATGAGGTTTATTTGGTTGAATCTGAGTTTAAAGAA
CAGCGCCATCTGACCGATCGCAGCTTGATCGATGGCGCCATCATTGTGAATGACGTTTCTTTCAAGTATGGATTTGGTCA
GGATATTTTGAAGCATGTCCATCTTGAAGTGCCCGCAAACGCTAAATACACGATTGTCGGCATGAGTGGGTCAGGTAAAT
CAACTTTGGCCAAATTATTGGTCGGTTTTTACCCGGTCGAAACAGGCAGGGGGAAAATCACTTTTAATGGCGCGCAGATC
GATGATGTGGCGCTCACGACGCTGCGGCAATATATCGAGTATGTGCCGCAAGAGCCGTTTATTTTTTCCGGATCGGTGAT
GGAAAACTTAACGTTAGGCAGTCGTGCCGATTTGACGCAGGCGCAACTTGAAGACGCATGTGCCGTTGCGGAGATTGCCA
CGGATATTATGAATTTGCCGCAAATGTGGCAGACCAAGCTCACGGAAAGCGGGAGCATTTTATCAGGTGGTCAGAAGCAG
CGCTTGGCGATTGCGCGGGCGTTGTTGTCGCCGGCCAAAGTGCTGATTTTTGATGAGTCGACTAGCAGTTTGGATACCAT
TACGGAGCGGCGGATTGTGGATCGGTTGTTGGCAATGAAGGATCGAACGATTATTTTTGTCGCCCACCGACTCACCATCG
CGGCTAAAACCGAACAGATTGTGGTGATGGATCATGGAGAAATTGTTGAGCAGGGCAATCATGCCGAACTGCTGGCGAAG
CAGGGATATTATGCGCGGTTGGTGAGTGAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (510-662)

• ABC transporter transmembrane region (ABC_membrane) (180-448)

• Peptidase C39 family (Peptidase_C39) (16-152)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus pneumoniae Rx1	58.357	98.356	0.574
comA	Streptococcus pneumoniae D39	58.357	98.356	0.574
comA	Streptococcus pneumoniae R6	58.357	98.356	0.574
comA	Streptococcus mitis NCTC 12261	58.217	98.356	0.573
comA	Streptococcus pneumoniae TIGR4	57.939	98.356	0.57
comA	Streptococcus mitis SK321	57.799	98.356	0.568
comA	Streptococcus gordonii str. Challis substr. CH1	56.964	98.356	0.56
comA/nlmT	Streptococcus mutans UA159	54.848	98.904	0.542