Detailed information NTG0867903

Bioinformatically predicted

Overview

• Name: pknB
• Type: Regulator
• Locus tag: Q9317_RS08145
• Genome accession: NZ_CP132230
• Coordinates: 1638767..1640671 (-)
• Length: 634 a.a.
• NCBI ID: WP_003101755.1
• Uniprot ID: -
• Organism: Streptococcus iniae strain BH15-2
• Function: modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology) Competence regulation

Genomic Context

Location: 1633767..1645671

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q9317_RS08115 (Q9317_08115)	tnpA	1633928..1634314 (+)	387	Protein_1566	IS200/IS605 family transposase	-
Q9317_RS08120 (Q9317_08120)	-	1634528..1634884 (-)	357	WP_003101745.1	S1 RNA-binding domain-containing protein	-
Q9317_RS08125 (Q9317_08125)	-	1634884..1636284 (-)	1401	WP_003101746.1	bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase	-
Q9317_RS08130 (Q9317_08130)	-	1636317..1636961 (-)	645	WP_003101747.1	response regulator transcription factor	-
Q9317_RS08135 (Q9317_08135)	-	1636954..1637958 (-)	1005	WP_003101748.1	sensor histidine kinase	-
Q9317_RS08140 (Q9317_08140)	liaF	1637955..1638650 (-)	696	WP_003101751.1	cell wall-active antibiotics response protein LiaF	-
Q9317_RS08145 (Q9317_08145)	pknB	1638767..1640671 (-)	1905	WP_003101755.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator
Q9317_RS08150 (Q9317_08150)	-	1640668..1641408 (-)	741	WP_003101757.1	Stp1/IreP family PP2C-type Ser/Thr phosphatase	-
Q9317_RS08155 (Q9317_08155)	rsmB	1641446..1642768 (-)	1323	WP_003101760.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
Q9317_RS08160 (Q9317_08160)	fmt	1642758..1643693 (-)	936	WP_003101762.1	methionyl-tRNA formyltransferase	-

Sequence

Protein

• Length: 634 a.a.
• Molecular weight: 69124.80 Da
• Isoelectric Point: 8.9521

>NTDB_id=867903 Q9317_RS08145 WP_003101755.1 1638767..1640671(-) (pknB) [Streptococcus iniae strain BH15-2]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEEVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYIQGADLKKFIQDNAPLSNTQVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENPQVP
QALENVVIKATAKKLSDRYNSTFEMSRDLMTALSYNRSRERKLVFLDVESTKPLPKVTPTPAPKPTVAPVSPSNTTKQKQ
EAIADVPVKKKKSGRFFGTLLKIIFALFVIGVAFFAFLVLTKPSTVKVPNVNGSSLAVAESELKSLGFKIGKVKEIESAT
VAEGNVVKTDPEAGTSKREGSKVDIYVSIGNQSFVMEDYKNQLYEDAVENLVNTYNVPRSKIKIERVVTSDYRKDMVIAQ
SPSPGEKFNPKGKSKIVLSVASNDTVLMPTIVNYTYQDALAALKALGIDSKRVKAYYPDVNSATGFSKMPNPKSTMIISA
QDPYAGVEISLSATSEISIYLYAEEPTANSSDTTTSSNSRSTASSSESHATSSSSSNPNAGTETNTDANVSPQN

Nucleotide

• Length: 1905 bp

>NTDB_id=867903 Q9317_RS08145 WP_003101755.1 1638767..1640671(-) (pknB) [Streptococcus iniae strain BH15-2]
ATGATACAGATTGGCAAATTATTTGCTGGTCGTTATCGCATCTTAAAATCAATTGGCCGCGGTGGTATGGCGGATGTTTA
CTTAGCCAATGACTTAATCTTAGATAATGAAGAAGTTGCAATTAAAGTTTTGCGAACCAATTATCAAACAGATCAAGTTG
CAGTAGCGCGTTTCCAAAGAGAAGCGCGAGCGATGGCAGAATTAAATCATCCCAACATTGTCGCTATTCGAGATATAGGT
GAAGAAGACGGACAGCAGTTCTTAGTAATGGAATATATCCAGGGCGCTGACCTTAAGAAATTTATTCAAGATAACGCTCC
TTTGTCTAACACCCAAGTTGTTAGAATCATGGAAGAAGTTTTATCTGCTATGACATTAGCCCACCAAAAAGGGATTGTTC
ATAGAGACTTGAAACCTCAAAATATTCTATTAACAAAGTCAGGTGTTGTCAAAGTTACAGACTTTGGTATTGCTGTAGCT
TTTGCTGAAACTAGTTTAACGCAGACAAATTCCATGTTAGGAAGTGTGCATTATTTATCACCAGAACAAGCCCGTGGTTC
AAAAGCCACCATTCAAAGTGATATTTATGCCATGGGAATTATGCTCTTTGAAATGTTAACAGGTCATATCCCATATGATG
GTGATAGTGCTGTTACAATTGCATTGCAGCATTTCCAAAAACCCCTTCCTTCAATTATTGACGAGAACCCGCAAGTTCCA
CAGGCTTTAGAAAATGTTGTTATTAAGGCAACTGCTAAAAAGTTAAGTGATCGTTACAATTCGACATTTGAAATGAGTCG
CGACCTAATGACTGCACTAAGTTATAATCGAAGCCGTGAACGCAAGTTAGTCTTTTTGGATGTTGAAAGCACAAAACCCT
TACCAAAAGTAACCCCGACCCCAGCACCAAAACCAACGGTAGCTCCGGTAAGTCCAAGTAATACCACTAAACAAAAACAA
GAAGCCATTGCTGATGTGCCTGTTAAGAAAAAAAAGAGTGGGCGTTTCTTTGGAACTTTATTAAAGATTATTTTTGCACT
ATTTGTTATCGGTGTTGCGTTTTTTGCCTTTCTTGTCTTGACCAAGCCATCTACCGTAAAAGTTCCAAATGTTAATGGAA
GTAGTCTAGCGGTTGCTGAATCAGAGTTAAAATCTTTAGGGTTTAAGATTGGAAAAGTAAAAGAAATTGAGAGTGCAACC
GTTGCAGAAGGTAATGTTGTTAAAACAGATCCAGAAGCTGGAACTTCAAAACGCGAAGGCTCTAAGGTTGATATTTATGT
TTCAATAGGTAATCAGAGTTTTGTGATGGAAGATTATAAAAATCAACTTTACGAAGATGCCGTTGAAAACCTTGTTAACA
CCTACAATGTTCCAAGGTCGAAAATTAAAATTGAAAGAGTGGTAACATCCGACTATCGTAAGGATATGGTTATTGCCCAG
TCACCTAGTCCAGGTGAGAAATTTAATCCCAAAGGAAAATCGAAGATTGTCCTCAGTGTGGCTAGTAATGACACAGTTTT
AATGCCAACTATTGTTAACTATACTTATCAGGATGCCCTTGCAGCACTAAAAGCTTTAGGAATTGACAGTAAGCGTGTCA
AAGCTTATTATCCTGATGTTAACTCTGCTACTGGCTTTAGCAAGATGCCTAATCCAAAATCAACAATGATTATCAGCGCA
CAAGATCCATATGCAGGTGTAGAGATTTCCTTATCTGCTACTAGCGAGATTAGCATTTACCTTTATGCTGAAGAACCAAC
AGCCAATAGTTCTGATACAACAACATCATCAAACAGTCGAAGTACAGCATCAAGTAGTGAGAGTCATGCCACAAGCAGCT
CATCCTCTAACCCTAACGCAGGTACCGAAACAAACACCGATGCCAATGTATCACCTCAAAACTAA

Domains

Predicted by InterproScan.

• Protein kinase domain (Pkinase) (12-241)

• PASTA domain (PASTA) (366-428)

• PASTA domain (PASTA) (435-501)

• PASTA domain (PASTA) (506-582)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pknB	Streptococcus mutans UA159	63.884	92.587	0.591
stkP/pknB	Streptococcus salivarius strain HSISS4	63.763	90.536	0.577
stkP	Streptococcus pneumoniae TIGR4	56.977	81.388	0.464
stkP	Streptococcus pneumoniae D39	56.589	81.388	0.461
stkP	Streptococcus pneumoniae R6	56.589	81.388	0.461
stkP	Streptococcus pneumoniae Rx1	56.395	81.388	0.459