Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   Q9318_RS06430 Genome accession   NZ_CP132229
Coordinates   1292372..1293217 (-) Length   281 a.a.
NCBI ID   WP_003099573.1    Uniprot ID   A0A1J0MYY1
Organism   Streptococcus iniae strain BH16-24     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1263094..1293217 1292372..1293217 within 0


Gene organization within MGE regions


Location: 1263094..1293217
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q9318_RS06280 (Q9318_06280) - 1263094..1263354 (-) 261 WP_003099631.1 DUF5960 family protein -
  Q9318_RS06285 (Q9318_06285) - 1263306..1263434 (-) 129 Protein_1190 ImpB/MucB/SamB family protein -
  Q9318_RS06290 (Q9318_06290) - 1263436..1264128 (-) 693 WP_003099630.1 helix-turn-helix transcriptional regulator -
  Q9318_RS06295 (Q9318_06295) - 1264299..1265327 (+) 1029 WP_003099629.1 Gfo/Idh/MocA family oxidoreductase -
  Q9318_RS06300 (Q9318_06300) - 1265451..1265873 (+) 423 WP_003099628.1 cupin domain-containing protein -
  Q9318_RS06305 (Q9318_06305) - 1266060..1266842 (+) 783 WP_003099627.1 threonine/serine exporter ThrE family protein -
  Q9318_RS06310 (Q9318_06310) - 1266833..1267270 (+) 438 WP_003099626.1 threonine/serine exporter family protein -
  Q9318_RS06315 (Q9318_06315) - 1267295..1268527 (-) 1233 WP_003099625.1 peptidoglycan bridge formation glycyltransferase FemA/FemB family protein -
  Q9318_RS06325 (Q9318_06325) - 1270617..1271698 (+) 1082 WP_305981612.1 IS3-like element IS981 family transposase -
  Q9318_RS06330 (Q9318_06330) - 1271764..1272869 (+) 1106 WP_089180041.1 IS3 family transposase -
  Q9318_RS06335 (Q9318_06335) - 1273206..1273700 (+) 495 WP_230453496.1 hypothetical protein -
  Q9318_RS06340 (Q9318_06340) - 1273714..1275219 (+) 1506 WP_037583453.1 serine/threonine-protein kinase -
  Q9318_RS06345 (Q9318_06345) - 1275236..1275490 (+) 255 WP_305981611.1 hypothetical protein -
  Q9318_RS06355 (Q9318_06355) - 1276784..1277086 (+) 303 WP_305981610.1 hypothetical protein -
  Q9318_RS06360 (Q9318_06360) xerS 1277300..1278370 (+) 1071 WP_003099620.1 tyrosine recombinase XerS -
  Q9318_RS06365 (Q9318_06365) - 1278459..1278794 (-) 336 WP_003099619.1 DUF5655 domain-containing protein -
  Q9318_RS06370 (Q9318_06370) - 1278796..1279742 (-) 947 Protein_1207 sensor histidine kinase -
  Q9318_RS06375 (Q9318_06375) - 1279739..1280404 (-) 666 WP_003099615.1 response regulator transcription factor -
  Q9318_RS06380 (Q9318_06380) - 1280447..1282402 (-) 1956 WP_003099611.1 ABC transporter permease -
  Q9318_RS06385 (Q9318_06385) - 1282404..1283156 (-) 753 WP_003099608.1 ABC transporter ATP-binding protein -
  Q9318_RS06390 (Q9318_06390) - 1283355..1283840 (+) 486 WP_305981609.1 PASTA domain-containing protein -
  Q9318_RS06395 (Q9318_06395) trmFO 1283979..1285313 (-) 1335 WP_003099603.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  Q9318_RS06400 (Q9318_06400) - 1285443..1286159 (-) 717 WP_031239171.1 DUF3307 domain-containing protein -
  Q9318_RS06405 (Q9318_06405) - 1286156..1286821 (-) 666 WP_003099599.1 SatD family protein -
  Q9318_RS06410 (Q9318_06410) - 1286927..1287919 (-) 993 WP_003099592.1 D-lactate dehydrogenase -
  Q9318_RS06415 (Q9318_06415) - 1287938..1288996 (-) 1059 WP_003099589.1 PTS transporter subunit IIC -
  Q9318_RS06420 (Q9318_06420) - 1289162..1290046 (+) 885 WP_003099578.1 LysR family transcriptional regulator -
  Q9318_RS06425 (Q9318_06425) topA 1290140..1292275 (-) 2136 WP_003099575.1 type I DNA topoisomerase -
  Q9318_RS06430 (Q9318_06430) dprA 1292372..1293217 (-) 846 WP_003099573.1 DNA-processing protein DprA Machinery gene

Sequence

Protein


Download         Length: 281 a.a.        Molecular weight: 31550.74 Da        Isoelectric Point: 9.9826

>NTDB_id=867848 Q9318_RS06430 WP_003099573.1 1292372..1293217(-) (dprA) [Streptococcus iniae strain BH16-24]
MNNFELYKLKKAGLKNHHILNIIHYSQQTKKSLSLRNMAVVSGTSKPCLFLENYKLLNIKELRVEFKKYPSFSILDKTYP
LALKEIDNPPVLLFYQGNLELLNRHKLAVVGSRKSSAVGNKSVESLIKQLNNQFVIVSGLARGIDTVAHFSSIKQGGETI
AVIGSGLDIYYPKENRRLQEFIAEKHLLLSEYCPKEAPLAHHFPERNRIIAGLSMGVLVAEAKWRSGSLITCRFALDYGR
DIFVVPGAILDKQSQGGNHLIQEGAKLVTKGLDIISEYQFL

Nucleotide


Download         Length: 846 bp        

>NTDB_id=867848 Q9318_RS06430 WP_003099573.1 1292372..1293217(-) (dprA) [Streptococcus iniae strain BH16-24]
ATGAATAACTTTGAACTGTATAAATTAAAGAAAGCTGGCCTAAAAAATCATCATATTCTAAATATCATTCATTATAGCCA
GCAAACTAAGAAATCTCTATCACTTAGAAATATGGCTGTTGTTTCAGGAACAAGTAAACCATGTCTGTTTTTAGAAAATT
ACAAGCTGTTAAATATAAAAGAGTTACGAGTAGAATTTAAGAAGTATCCCAGCTTTTCAATTTTAGACAAGACCTATCCC
CTTGCTTTAAAAGAAATTGATAATCCGCCAGTATTATTATTTTATCAAGGAAATTTAGAGCTTTTAAATCGGCATAAATT
AGCAGTGGTAGGGTCAAGGAAATCCTCAGCAGTTGGAAACAAATCTGTTGAATCTCTCATCAAGCAACTTAATAATCAGT
TTGTTATTGTTAGTGGGTTGGCTAGAGGAATTGATACTGTAGCTCATTTTTCGAGCATCAAACAAGGTGGAGAGACTATT
GCTGTTATTGGATCAGGGTTAGACATTTATTATCCTAAGGAAAATAGAAGATTACAGGAGTTTATTGCTGAAAAGCATTT
ATTATTAAGTGAATATTGCCCTAAGGAAGCACCTTTAGCACATCATTTTCCAGAACGAAATCGCATAATTGCAGGCTTAT
CTATGGGAGTTTTAGTGGCAGAAGCCAAATGGCGTTCTGGTAGTCTAATCACTTGTCGCTTTGCACTTGATTACGGTAGG
GATATTTTTGTTGTTCCAGGCGCCATCCTTGACAAACAGTCGCAGGGAGGGAATCACCTCATTCAAGAGGGAGCGAAGCT
TGTTACAAAAGGACTTGACATCATTTCTGAATACCAATTTTTATAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-62)

DNA recombination-mediator protein A (DNA_processg_A)

(73-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1J0MYY1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

66.786

99.644

0.665
  dprA/cilB/dalA Streptococcus mitis SK321

57.5

99.644

0.573
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

57.143

99.644

0.569
  dprA/cilB/dalA Streptococcus pneumoniae D39

57.143

99.644

0.569
  dprA/cilB/dalA Streptococcus pneumoniae R6

57.143

99.644

0.569
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

57.143

99.644

0.569
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

56.786

99.644

0.566
  dprA Lactococcus lactis subsp. cremoris KW2

54.643

99.644

0.544