Detailed information NTG0867831

Bioinformatically predicted

Overview

• Name: pknB
• Type: Regulator
• Locus tag: Q9318_RS03435
• Genome accession: NZ_CP132229
• Coordinates: 684771..686675 (+)
• Length: 634 a.a.
• NCBI ID: WP_003101755.1
• Uniprot ID: -
• Organism: Streptococcus iniae strain BH16-24
• Function: modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology) Competence regulation

Genomic Context

Location: 679771..691675

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q9318_RS03420 (Q9318_03420)	fmt	681749..682684 (+)	936	WP_003101762.1	methionyl-tRNA formyltransferase	-
Q9318_RS03425 (Q9318_03425)	rsmB	682674..683996 (+)	1323	WP_003101760.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
Q9318_RS03430 (Q9318_03430)	-	684034..684774 (+)	741	WP_003101757.1	Stp1/IreP family PP2C-type Ser/Thr phosphatase	-
Q9318_RS03435 (Q9318_03435)	pknB	684771..686675 (+)	1905	WP_003101755.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator
Q9318_RS03440 (Q9318_03440)	liaF	686792..687487 (+)	696	WP_003101751.1	cell wall-active antibiotics response protein LiaF	-
Q9318_RS03445 (Q9318_03445)	-	687484..688488 (+)	1005	WP_003101748.1	sensor histidine kinase	-
Q9318_RS03450 (Q9318_03450)	-	688481..689125 (+)	645	WP_003101747.1	response regulator transcription factor	-
Q9318_RS03455 (Q9318_03455)	-	689158..690558 (+)	1401	WP_003101746.1	bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase	-
Q9318_RS03460 (Q9318_03460)	-	690558..690914 (+)	357	WP_003101745.1	S1 RNA-binding domain-containing protein	-
Q9318_RS03465 (Q9318_03465)	tnpA	691128..691514 (-)	387	Protein_631	IS200/IS605 family transposase	-

Sequence

Protein

• Length: 634 a.a.
• Molecular weight: 69124.80 Da
• Isoelectric Point: 8.9521

>NTDB_id=867831 Q9318_RS03435 WP_003101755.1 684771..686675(+) (pknB) [Streptococcus iniae strain BH16-24]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEEVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYIQGADLKKFIQDNAPLSNTQVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENPQVP
QALENVVIKATAKKLSDRYNSTFEMSRDLMTALSYNRSRERKLVFLDVESTKPLPKVTPTPAPKPTVAPVSPSNTTKQKQ
EAIADVPVKKKKSGRFFGTLLKIIFALFVIGVAFFAFLVLTKPSTVKVPNVNGSSLAVAESELKSLGFKIGKVKEIESAT
VAEGNVVKTDPEAGTSKREGSKVDIYVSIGNQSFVMEDYKNQLYEDAVENLVNTYNVPRSKIKIERVVTSDYRKDMVIAQ
SPSPGEKFNPKGKSKIVLSVASNDTVLMPTIVNYTYQDALAALKALGIDSKRVKAYYPDVNSATGFSKMPNPKSTMIISA
QDPYAGVEISLSATSEISIYLYAEEPTANSSDTTTSSNSRSTASSSESHATSSSSSNPNAGTETNTDANVSPQN

Nucleotide

• Length: 1905 bp

>NTDB_id=867831 Q9318_RS03435 WP_003101755.1 684771..686675(+) (pknB) [Streptococcus iniae strain BH16-24]
ATGATACAGATTGGCAAATTATTTGCTGGTCGTTATCGCATCTTAAAATCAATTGGCCGCGGTGGTATGGCGGATGTTTA
CTTAGCCAATGACTTAATCTTAGATAATGAAGAAGTTGCAATTAAAGTTTTGCGAACCAATTATCAAACAGATCAAGTTG
CAGTAGCGCGTTTCCAAAGAGAAGCGCGAGCGATGGCAGAATTAAATCATCCCAACATTGTCGCTATTCGAGATATAGGT
GAAGAAGACGGACAGCAGTTCTTAGTAATGGAATATATCCAGGGCGCTGACCTTAAGAAATTTATTCAAGATAACGCTCC
TTTGTCTAACACCCAAGTTGTTAGAATCATGGAAGAAGTTTTATCTGCTATGACATTAGCCCACCAAAAAGGGATTGTTC
ATAGAGACTTGAAACCTCAAAATATTCTATTAACAAAGTCAGGTGTTGTCAAAGTTACAGACTTTGGTATTGCTGTAGCT
TTTGCTGAAACTAGTTTAACGCAGACAAATTCCATGTTAGGAAGTGTGCATTATTTATCACCAGAACAAGCCCGTGGTTC
AAAAGCCACCATTCAAAGTGATATTTATGCCATGGGAATTATGCTCTTTGAAATGTTAACAGGTCATATCCCATATGATG
GTGATAGTGCTGTTACAATTGCATTGCAGCATTTCCAAAAACCCCTTCCTTCAATTATTGACGAGAACCCGCAAGTTCCA
CAGGCTTTAGAAAATGTTGTTATTAAGGCAACTGCTAAAAAGTTAAGTGATCGTTACAATTCGACATTTGAAATGAGTCG
CGACCTAATGACTGCACTAAGTTATAATCGAAGCCGTGAACGCAAGTTAGTCTTTTTGGATGTTGAAAGCACAAAACCCT
TACCAAAAGTAACCCCGACCCCAGCACCAAAACCAACGGTAGCTCCGGTAAGTCCAAGTAATACCACTAAACAAAAACAA
GAAGCCATTGCTGATGTGCCTGTTAAGAAAAAAAAGAGTGGGCGTTTCTTTGGAACTTTATTAAAGATTATTTTTGCACT
ATTTGTTATCGGTGTTGCGTTTTTTGCCTTTCTTGTCTTGACCAAGCCATCTACCGTAAAAGTTCCAAATGTTAATGGAA
GTAGTCTAGCGGTTGCTGAATCAGAGTTAAAATCTTTAGGGTTTAAGATTGGAAAAGTAAAAGAAATTGAGAGTGCAACC
GTTGCAGAAGGTAATGTTGTTAAAACAGATCCAGAAGCTGGAACTTCAAAACGCGAAGGCTCTAAGGTTGATATTTATGT
TTCAATAGGTAATCAGAGTTTTGTGATGGAAGATTATAAAAATCAACTTTACGAAGATGCCGTTGAAAACCTTGTTAACA
CCTACAATGTTCCAAGGTCGAAAATTAAAATTGAAAGAGTGGTAACATCCGACTATCGTAAGGATATGGTTATTGCCCAG
TCACCTAGTCCAGGTGAGAAATTTAATCCCAAAGGAAAATCGAAGATTGTCCTCAGTGTGGCTAGTAATGACACAGTTTT
AATGCCAACTATTGTTAACTATACTTATCAGGATGCCCTTGCAGCACTAAAAGCTTTAGGAATTGACAGTAAGCGTGTCA
AAGCTTATTATCCTGATGTTAACTCTGCTACTGGCTTTAGCAAGATGCCTAATCCAAAATCAACAATGATTATCAGCGCA
CAAGATCCATATGCAGGTGTAGAGATTTCCTTATCTGCTACTAGCGAGATTAGCATTTACCTTTATGCTGAAGAACCAAC
AGCCAATAGTTCTGATACAACAACATCATCAAACAGTCGAAGTACAGCATCAAGTAGTGAGAGTCATGCCACAAGCAGCT
CATCCTCTAACCCTAACGCAGGTACCGAAACAAACACCGATGCCAATGTATCACCTCAAAACTAA

Domains

Predicted by InterproScan.

• Protein kinase domain (Pkinase) (12-241)

• PASTA domain (PASTA) (366-428)

• PASTA domain (PASTA) (435-501)

• PASTA domain (PASTA) (506-582)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pknB	Streptococcus mutans UA159	63.884	92.587	0.591
stkP/pknB	Streptococcus salivarius strain HSISS4	63.763	90.536	0.577
stkP	Streptococcus pneumoniae TIGR4	56.977	81.388	0.464
stkP	Streptococcus pneumoniae D39	56.589	81.388	0.461
stkP	Streptococcus pneumoniae R6	56.589	81.388	0.461
stkP	Streptococcus pneumoniae Rx1	56.395	81.388	0.459