Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   Q7609_RS04030 Genome accession   NZ_CP131725
Coordinates   780810..782030 (+) Length   406 a.a.
NCBI ID   WP_342123402.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 2018S05-172     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 775810..787030
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7609_RS04010 (Q7609_04010) corC 776784..777683 (-) 900 WP_005654105.1 CNNM family magnesium/cobalt transport protein CorC -
  Q7609_RS04015 (Q7609_04015) ampD 778316..778870 (-) 555 WP_342123399.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  Q7609_RS04020 (Q7609_04020) pilA 778985..779425 (+) 441 WP_342123400.1 prepilin peptidase-dependent pilin Machinery gene
  Q7609_RS04025 (Q7609_04025) pilB 779422..780813 (+) 1392 WP_342123401.1 GspE/PulE family protein Machinery gene
  Q7609_RS04030 (Q7609_04030) pilC 780810..782030 (+) 1221 WP_342123402.1 type II secretion system F family protein Machinery gene
  Q7609_RS04035 (Q7609_04035) pilD 782027..782719 (+) 693 WP_342123403.1 A24 family peptidase Machinery gene
  Q7609_RS04040 (Q7609_04040) rho 782773..784035 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  Q7609_RS04045 (Q7609_04045) metJ 784283..784600 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  Q7609_RS04050 (Q7609_04050) cueR 784614..785000 (-) 387 WP_005654127.1 Cu(I)-responsive transcriptional regulator -
  Q7609_RS04055 (Q7609_04055) - 785077..785283 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  Q7609_RS04060 (Q7609_04060) - 785369..785575 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  Q7609_RS04065 (Q7609_04065) - 785649..785855 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46277.50 Da        Isoelectric Point: 9.7826

>NTDB_id=864872 Q7609_RS04030 WP_342123402.1 780810..782030(+) (pilC) [Haemophilus influenzae strain 2018S05-172]
MTKKLFYYQASNPLNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIVLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFVLSFFLFYYFYLKRQTWF
YQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=864872 Q7609_RS04030 WP_342123402.1 780810..782030(+) (pilC) [Haemophilus influenzae strain 2018S05-172]
ATGACTAAAAAACTCTTTTATTATCAAGCTAGTAACCCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCACACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATTAGCGAATTACTCAATCAATTAGCCACGTTGCTACAATCCGCTATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTGTACTCAATGAATGGCTTGAACGACTACTTCAATCTATTGAATCTGGTTT
AGCATTCTCACAAGCCATTGAACAACAAGGGAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACACATCGCAGCCAATCTTTAGCATTACAACGTAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCGGAGTTACCAACAATAACCGCAATATTGCTCTCAATATCTAATTTCCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGTTTTGAGTTTTTTTCTATTTTATTATTTCTATCTAAAACGCCAGACTTGGTTT
TATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAAGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTTCCTCGCACACAAACGT
GGCAAACCAAGAAAACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGC
TATGCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTCCAAATTGGCGAACAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

99.507

100

0.995
  pilC Haemophilus influenzae 86-028NP

97.783

100

0.978
  pilC Glaesserella parasuis strain SC1401

38.653

98.768

0.382