Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   Q7612_RS04150 Genome accession   NZ_CP131722
Coordinates   801162..802379 (+) Length   405 a.a.
NCBI ID   WP_061724182.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 2018C09-260     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 796162..807379
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7612_RS04130 (Q7612_04120) corC 797129..798028 (-) 900 WP_005656283.1 CNNM family magnesium/cobalt transport protein CorC -
  Q7612_RS04135 (Q7612_04125) ampD 798650..799210 (-) 561 WP_042599472.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  Q7612_RS04140 (Q7612_04130) pilA 799325..799774 (+) 450 WP_048954594.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  Q7612_RS04145 (Q7612_04135) pilB 799771..801165 (+) 1395 WP_061724184.1 GspE/PulE family protein Machinery gene
  Q7612_RS04150 (Q7612_04140) pilC 801162..802379 (+) 1218 WP_061724182.1 type II secretion system F family protein Machinery gene
  Q7612_RS04155 (Q7612_04145) pilD 802376..803068 (+) 693 WP_048954597.1 A24 family peptidase Machinery gene
  Q7612_RS04160 (Q7612_04150) rho 803122..804384 (-) 1263 WP_005666690.1 transcription termination factor Rho -
  Q7612_RS04165 (Q7612_04155) metJ 804632..804949 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  Q7612_RS04170 (Q7612_04160) cueR 804963..805349 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  Q7612_RS04175 (Q7612_04165) - 805426..805632 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  Q7612_RS04180 (Q7612_04170) - 805706..805912 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  Q7612_RS04185 (Q7612_04175) - 805986..806192 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46201.44 Da        Isoelectric Point: 9.7235

>NTDB_id=864762 Q7612_RS04150 WP_061724182.1 801162..802379(+) (pilC) [Haemophilus influenzae strain 2018C09-260]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISHGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQKISILLFFAFSFFLFYYFYLKRQIWF
HQQKNQLISVMPIFGTIQKLSRLVNFSQSLQIMLQAGIPLNQALDSFLPRTQTWQTKTLVNDIILDKEVRSILQWVSQGY
AFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=864762 Q7612_RS04150 WP_061724182.1 801162..802379(+) (pilC) [Haemophilus influenzae strain 2018C09-260]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAGTTAATAAGCCACGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAAC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGCAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAATGAATGGCTTGAACGGCTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCCATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGTCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTAGGAATTTCACTATTACTAACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCCGAATTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAAGATTAGCATTTTGCTATTTTTCGCTTTTAGTTTTTTTCTATTTTATTACTTCTATCTAAAACGCCAGATCTGGTTT
CATCAACAGAAAAACCAACTTATCTCTGTCATGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTACAGGCTGGCATTCCGCTTAATCAAGCACTAGACAGTTTTCTTCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCATATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTAATAGCGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTAGAGCATATCGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTGATCATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

96.059

100

0.963
  pilC Haemophilus influenzae Rd KW20

95.813

100

0.96
  pilC Glaesserella parasuis strain SC1401

39

98.765

0.385