Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Machinery gene
Locus tag   Q7612_RS03135 Genome accession   NZ_CP131722
Coordinates   629145..629558 (+) Length   137 a.a.
NCBI ID   WP_126513465.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 2018C09-260     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 624145..634558
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7612_RS03115 (Q7612_03110) - 624633..627227 (-) 2595 WP_342123008.1 penicillin-binding protein 1A -
  Q7612_RS03120 (Q7612_03115) comA 627326..628123 (+) 798 WP_005649306.1 pilus assembly protein PilM Machinery gene
  Q7612_RS03125 (Q7612_03120) comB 628124..628630 (+) 507 WP_005649305.1 competence protein ComB Machinery gene
  Q7612_RS03130 (Q7612_03125) comC 628627..629148 (+) 522 WP_005649304.1 competence protein ComC Machinery gene
  Q7612_RS03135 (Q7612_03130) comD 629145..629558 (+) 414 WP_126513465.1 pilus assembly protein PilP Machinery gene
  Q7612_RS03140 (Q7612_03135) comE 629568..630905 (+) 1338 WP_126513466.1 type IV pilus secretin PilQ family protein Machinery gene
  Q7612_RS03145 (Q7612_03140) - 630918..631604 (+) 687 WP_126513467.1 ComF family protein -
  Q7612_RS03150 (Q7612_03145) nfuA 631680..632276 (+) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  Q7612_RS03155 (Q7612_03150) nudC 632343..633137 (+) 795 WP_005666520.1 NAD(+) diphosphatase -
  Q7612_RS03160 (Q7612_03155) - 633173..633763 (+) 591 WP_005649296.1 YjaG family protein -
  Q7612_RS03165 (Q7612_03160) - 633903..634175 (+) 273 WP_005630954.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 137 a.a.        Molecular weight: 15700.92 Da        Isoelectric Point: 4.9103

>NTDB_id=864753 Q7612_RS03135 WP_126513465.1 629145..629558(+) (comD) [Haemophilus influenzae strain 2018C09-260]
MKHWFFLIILFFMNCSWGQDPFDKTQRNRSQFDNAQTVMEQTEIISSDVPNNLCGADEHRQAAEIPLNALKLVGVVISKD
KAFALLQDQALQIYSVLEGVDVAQEGYVVTKINQNKVQFMRKLGEQCDRAEQKELSF

Nucleotide


Download         Length: 414 bp        

>NTDB_id=864753 Q7612_RS03135 WP_126513465.1 629145..629558(+) (comD) [Haemophilus influenzae strain 2018C09-260]
ATGAAACATTGGTTTTTCCTGATTATATTATTTTTTATGAATTGCAGTTGGGGACAAGATCCTTTCGATAAAACACAGCG
TAACCGTTCTCAGTTTGATAACGCACAAACAGTAATGGAACAGACAGAAATAATTTCCTCAGATGTACCTAATAATCTAT
GCGGAGCGGATGAACATCGCCAAGCGGCTGAAATTCCTTTGAACGCTTTAAAATTGGTGGGGGTAGTGATTTCTAAAGAT
AAAGCCTTTGCATTATTGCAGGATCAGGCTTTGCAAATTTACAGCGTTTTAGAAGGTGTTGATGTGGCTCAAGAAGGATA
TGTTGTAACAAAAATCAATCAAAATAAAGTTCAATTTATGCGTAAGCTCGGTGAGCAATGTGATAGAGCTGAACAGAAAG
AATTAAGTTTTTAA

Domains

Predicted by InterproScan.

Pilus assembly protein, PilP (PilP)

(26-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Haemophilus influenzae 86-028NP

93.431

100

0.934
  comD Haemophilus influenzae Rd KW20

92.701

100

0.927