Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Machinery gene
Locus tag   Q7612_RS03125 Genome accession   NZ_CP131722
Coordinates   628124..628630 (+) Length   168 a.a.
NCBI ID   WP_005649305.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 2018C09-260     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 623124..633630
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7612_RS03105 (Q7612_03100) - 623233..623562 (-) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -
  Q7612_RS03110 (Q7612_03105) - 623715..624560 (-) 846 WP_005666516.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  Q7612_RS03115 (Q7612_03110) - 624633..627227 (-) 2595 WP_342123008.1 penicillin-binding protein 1A -
  Q7612_RS03120 (Q7612_03115) comA 627326..628123 (+) 798 WP_005649306.1 pilus assembly protein PilM Machinery gene
  Q7612_RS03125 (Q7612_03120) comB 628124..628630 (+) 507 WP_005649305.1 competence protein ComB Machinery gene
  Q7612_RS03130 (Q7612_03125) comC 628627..629148 (+) 522 WP_005649304.1 competence protein ComC Machinery gene
  Q7612_RS03135 (Q7612_03130) comD 629145..629558 (+) 414 WP_126513465.1 pilus assembly protein PilP Machinery gene
  Q7612_RS03140 (Q7612_03135) comE 629568..630905 (+) 1338 WP_126513466.1 type IV pilus secretin PilQ family protein Machinery gene
  Q7612_RS03145 (Q7612_03140) - 630918..631604 (+) 687 WP_126513467.1 ComF family protein -
  Q7612_RS03150 (Q7612_03145) nfuA 631680..632276 (+) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  Q7612_RS03155 (Q7612_03150) nudC 632343..633137 (+) 795 WP_005666520.1 NAD(+) diphosphatase -

Sequence

Protein


Download         Length: 168 a.a.        Molecular weight: 19724.61 Da        Isoelectric Point: 8.5473

>NTDB_id=864751 Q7612_RS03125 WP_005649305.1 628124..628630(+) (comB) [Haemophilus influenzae strain 2018C09-260]
MSMNLLPWRTYQHQKRLRRLAFYIALFILLAINLMLAFSNLIEQQKQNLQAQQKSFEQLNQQLHKTTMQIDQLRSAVKVG
EVLTSIPNEQVKKSLQQLSELPFQQGELNKFKQDANNLSLEGNAQDQTEFELIHQFLKKHFPNVKLSQVQPEQDTLFFHF
DVEQGAEK

Nucleotide


Download         Length: 507 bp        

>NTDB_id=864751 Q7612_RS03125 WP_005649305.1 628124..628630(+) (comB) [Haemophilus influenzae strain 2018C09-260]
ATGTCGATGAATTTATTGCCTTGGCGTACTTATCAACATCAAAAGCGTTTACGTCGTTTAGCTTTTTATATCGCTTTATT
TATCTTGCTTGCTATTAATTTAATGTTGGCTTTTAGCAATTTGATTGAACAACAGAAACAAAATTTGCAGGCACAGCAAA
AGTCGTTTGAACAACTTAATCAACAGCTTCATAAAACTACCATGCAAATTGATCAGTTACGCAGTGCGGTGAAAGTTGGT
GAAGTTTTGACATCTATTCCCAACGAGCAAGTAAAAAAGAGTTTACAACAGCTAAGTGAATTACCTTTTCAACAAGGAGA
ACTGAATAAATTTAAACAAGATGCGAATAACTTAAGTTTGGAAGGTAACGCGCAAGATCAAACAGAATTTGAACTGATTC
ATCAATTTTTAAAGAAACATTTTCCCAATGTGAAATTAAGTCAGGTTCAACCTGAACAAGATACATTGTTTTTTCACTTT
GATGTGGAACAAGGGGCGGAAAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Haemophilus influenzae 86-028NP

99.405

100

0.994
  comB Haemophilus influenzae Rd KW20

99.405

100

0.994