Detailed information NTG0864378

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: Q7620_RS10060
• Genome accession: NZ_CP131713
• Coordinates: 1938722..1939183 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250531.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2008C09-276
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1933722..1944183

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7620_RS10025 (Q7620_09995)	-	1934029..1934853 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
Q7620_RS10030 (Q7620_10000)	rnpA	1934828..1935199 (-)	372	WP_000739246.1	ribonuclease P protein component	-
Q7620_RS10035 (Q7620_10005)	-	1935216..1935347 (-)	132	WP_000768904.1	hypothetical protein	-
Q7620_RS10040 (Q7620_10010)	-	1935348..1936538 (-)	1191	WP_000167765.1	acetate kinase	-
Q7620_RS10045 (Q7620_10015)	comYH	1936589..1937542 (-)	954	WP_000345126.1	class I SAM-dependent methyltransferase	Machinery gene
Q7620_RS10050 (Q7620_10020)	-	1937603..1938195 (-)	593	Protein_1954	methyltransferase domain-containing protein	-
Q7620_RS10055 (Q7620_10025)	comGG/cglG	1938298..1938744 (-)	447	WP_001809944.1	competence type IV pilus minor pilin ComGG	Machinery gene
Q7620_RS10060 (Q7620_10030)	comGF/cglF	1938722..1939183 (-)	462	WP_000250531.1	competence type IV pilus minor pilin ComGF	Machinery gene
Q7620_RS10065 (Q7620_10035)	comGE/cglE	1939146..1939448 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
Q7620_RS10070 (Q7620_10040)	comGD/cglD	1939411..1939845 (-)	435	WP_033606693.1	competence type IV pilus minor pilin ComGD	Machinery gene
Q7620_RS10075 (Q7620_10045)	comGC/cglC	1939808..1940131 (-)	324	WP_000738628.1	comG operon protein ComGC	Machinery gene
Q7620_RS10080 (Q7620_10050)	comGB/cglB	1940133..1941149 (-)	1017	WP_078130737.1	competence type IV pilus assembly protein ComGB	Machinery gene
Q7620_RS10085 (Q7620_10055)	comGA/cglA/cilD	1941097..1942038 (-)	942	WP_000249536.1	competence type IV pilus ATPase ComGA	Machinery gene
Q7620_RS10090 (Q7620_10060)	-	1942114..1942479 (-)	366	WP_054407367.1	DUF1033 family protein	-
Q7620_RS10095 (Q7620_10065)	-	1942630..1943688 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17849.37 Da
• Isoelectric Point: 6.4832

>NTDB_id=864378 Q7620_RS10060 WP_000250531.1 1938722..1939183(-) (comGF/cglF) [Streptococcus pneumoniae strain 2008C09-276]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=864378 Q7620_RS10060 WP_000250531.1 1938722..1939183(-) (comGF/cglF) [Streptococcus pneumoniae strain 2008C09-276]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae D39	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae R6	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae TIGR4	95.425	100	0.954
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915