Detailed information NTG0864299

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: Q7621_RS09985
• Genome accession: NZ_CP131712
• Coordinates: 1995687..1996148 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250539.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2008C09-280
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1990687..2001148

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7621_RS09950 (Q7621_09945)	-	1990992..1991816 (-)	825	WP_341966576.1	membrane protein insertase YidC	-
Q7621_RS09955 (Q7621_09950)	rnpA	1991791..1992162 (-)	372	WP_000739246.1	ribonuclease P protein component	-
Q7621_RS09960 (Q7621_09955)	-	1992179..1992310 (-)	132	WP_000768904.1	hypothetical protein	-
Q7621_RS09965 (Q7621_09960)	-	1992311..1993501 (-)	1191	WP_000167766.1	acetate kinase	-
Q7621_RS09970 (Q7621_09965)	comYH	1993552..1994505 (-)	954	WP_000345133.1	class I SAM-dependent methyltransferase	Machinery gene
Q7621_RS09975 (Q7621_09970)	-	1994566..1995160 (-)	595	Protein_1940	methyltransferase domain-containing protein	-
Q7621_RS09980 (Q7621_09975)	comGG/cglG	1995263..1995709 (-)	447	WP_001811371.1	competence type IV pilus minor pilin ComGG	Machinery gene
Q7621_RS09985 (Q7621_09980)	comGF/cglF	1995687..1996148 (-)	462	WP_000250539.1	competence type IV pilus minor pilin ComGF	Machinery gene
Q7621_RS09990 (Q7621_09985)	comGE/cglE	1996111..1996413 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
Q7621_RS09995 (Q7621_09990)	comGD/cglD	1996376..1996780 (-)	405	WP_000588030.1	competence type IV pilus minor pilin ComGD	Machinery gene
Q7621_RS10000 (Q7621_09995)	comGC/cglC	1996773..1997099 (-)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
Q7621_RS10005 (Q7621_10000)	comGB/cglB	1997101..1998117 (-)	1017	WP_078134418.1	competence type IV pilus assembly protein ComGB	Machinery gene
Q7621_RS10010 (Q7621_10005)	comGA/cglA/cilD	1998065..1999006 (-)	942	WP_000249573.1	competence type IV pilus ATPase ComGA	Machinery gene
Q7621_RS10015 (Q7621_10010)	-	1999082..1999447 (-)	366	WP_000286415.1	DUF1033 family protein	-
Q7621_RS10020 (Q7621_10015)	-	1999598..2000656 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17851.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=864299 Q7621_RS09985 WP_000250539.1 1995687..1996148(-) (comGF/cglF) [Streptococcus pneumoniae strain 2008C09-280]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=864299 Q7621_RS09985 WP_000250539.1 1995687..1996148(-) (comGF/cglF) [Streptococcus pneumoniae strain 2008C09-280]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae D39	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae R6	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae TIGR4	94.118	100	0.941
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915