Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   Q7621_RS09970 Genome accession   NZ_CP131712
Coordinates   1993552..1994505 (-) Length   317 a.a.
NCBI ID   WP_000345133.1    Uniprot ID   A0A0T8FEM8
Organism   Streptococcus pneumoniae strain 2008C09-280     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1988552..1999505
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7621_RS09940 (Q7621_09935) - 1989313..1989936 (-) 624 WP_000932661.1 hypothetical protein -
  Q7621_RS09945 (Q7621_09940) jag 1989987..1990973 (-) 987 WP_000260018.1 RNA-binding cell elongation regulator Jag/EloR -
  Q7621_RS09950 (Q7621_09945) - 1990992..1991816 (-) 825 WP_341966576.1 membrane protein insertase YidC -
  Q7621_RS09955 (Q7621_09950) rnpA 1991791..1992162 (-) 372 WP_000739246.1 ribonuclease P protein component -
  Q7621_RS09960 (Q7621_09955) - 1992179..1992310 (-) 132 WP_000768904.1 hypothetical protein -
  Q7621_RS09965 (Q7621_09960) - 1992311..1993501 (-) 1191 WP_000167766.1 acetate kinase -
  Q7621_RS09970 (Q7621_09965) comYH 1993552..1994505 (-) 954 WP_000345133.1 class I SAM-dependent methyltransferase Machinery gene
  Q7621_RS09975 (Q7621_09970) - 1994566..1995160 (-) 595 Protein_1940 methyltransferase domain-containing protein -
  Q7621_RS09980 (Q7621_09975) comGG/cglG 1995263..1995709 (-) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  Q7621_RS09985 (Q7621_09980) comGF/cglF 1995687..1996148 (-) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  Q7621_RS09990 (Q7621_09985) comGE/cglE 1996111..1996413 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  Q7621_RS09995 (Q7621_09990) comGD/cglD 1996376..1996780 (-) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  Q7621_RS10000 (Q7621_09995) comGC/cglC 1996773..1997099 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  Q7621_RS10005 (Q7621_10000) comGB/cglB 1997101..1998117 (-) 1017 WP_078134418.1 competence type IV pilus assembly protein ComGB Machinery gene
  Q7621_RS10010 (Q7621_10005) comGA/cglA/cilD 1998065..1999006 (-) 942 WP_000249573.1 competence type IV pilus ATPase ComGA Machinery gene
  Q7621_RS10015 (Q7621_10010) - 1999082..1999447 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35721.90 Da        Isoelectric Point: 4.2665

>NTDB_id=864297 Q7621_RS09970 WP_000345133.1 1993552..1994505(-) (comYH) [Streptococcus pneumoniae strain 2008C09-280]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGFKYLKSDGYAIFLAPSDLLTSPQ
SDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=864297 Q7621_RS09970 WP_000345133.1 1993552..1994505(-) (comYH) [Streptococcus pneumoniae strain 2008C09-280]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAATAGCATCTATCTGGATGGTGAAACTGAGTTAAACCAGGTCAAAGACAACAATC
AAACCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGCCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTCGG
CTATTATCCTGATGATGCCGTTGCGTCGCGTCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCTCATCACTTGCTCA
TGGAACAAGGGTTTAAGTACCTTAAGTCAGATGGATATGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTGAAAGTCTGGTTGAAAGAGGAGGCAAGTCTGGTTGCTATGATTAGTTTACCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTGGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T8FEM8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536