Detailed information NTG0864031

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: Q7624_RS05830
• Genome accession: NZ_CP131709
• Coordinates: 1148325..1149278 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain 2016S11-245
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1143325..1154278

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7624_RS05805 (Q7624_05785)	-	1143806..1143901 (-)	96	Protein_1149	IS630 family transposase	-
Q7624_RS05810 (Q7624_05790)	-	1144314..1144655 (+)	342	Protein_1150	IS3 family transposase	-
Q7624_RS05815 (Q7624_05795)	prsA	1144772..1145713 (-)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
Q7624_RS05820 (Q7624_05800)	-	1145780..1146493 (-)	714	WP_000230400.1	O-methyltransferase	-
Q7624_RS05825 (Q7624_05805)	pepF	1146495..1148306 (-)	1812	WP_000244158.1	oligoendopeptidase F	Regulator
Q7624_RS05830 (Q7624_05810)	coiA	1148325..1149278 (-)	954	WP_000495909.1	competence protein CoiA	Machinery gene
Q7624_RS05835 (Q7624_05815)	tehB	1149351..1150211 (-)	861	WP_000413757.1	SAM-dependent methyltransferase TehB	-
Q7624_RS05840 (Q7624_05820)	smpB	1150227..1150694 (-)	468	WP_001051750.1	SsrA-binding protein SmpB	-
Q7624_RS05845 (Q7624_05825)	rnr	1150657..1153011 (-)	2355	WP_000654886.1	ribonuclease R	-
Q7624_RS05850 (Q7624_05830)	secG	1153113..1153346 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
Q7624_RS05855 (Q7624_05835)	rpmG	1153386..1153535 (-)	150	WP_001810029.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=864031 Q7624_RS05830 WP_000495909.1 1148325..1149278(-) (coiA) [Streptococcus pneumoniae strain 2016S11-245]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=864031 Q7624_RS05830 WP_000495909.1 1148325..1149278(-) (coiA) [Streptococcus pneumoniae strain 2016S11-245]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTAAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435