Detailed information NTG0863992

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: Q7625_RS10030
• Genome accession: NZ_CP131708
• Coordinates: 1959911..1960372 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250539.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2016C10-332
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1954911..1965372

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7625_RS09995 (Q7625_09980)	-	1955216..1956040 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
Q7625_RS10000 (Q7625_09985)	rnpA	1956015..1956386 (-)	372	WP_000739246.1	ribonuclease P protein component	-
Q7625_RS10005 (Q7625_09990)	-	1956403..1956534 (-)	132	WP_000768904.1	hypothetical protein	-
Q7625_RS10010 (Q7625_09995)	-	1956535..1957725 (-)	1191	WP_000167766.1	acetate kinase	-
Q7625_RS10015 (Q7625_10000)	comYH	1957776..1958729 (-)	954	WP_000345133.1	class I SAM-dependent methyltransferase	Machinery gene
Q7625_RS10020 (Q7625_10005)	-	1958790..1959384 (-)	595	Protein_1949	methyltransferase domain-containing protein	-
Q7625_RS10025 (Q7625_10010)	comGG/cglG	1959487..1959933 (-)	447	WP_001811371.1	competence type IV pilus minor pilin ComGG	Machinery gene
Q7625_RS10030 (Q7625_10015)	comGF/cglF	1959911..1960372 (-)	462	WP_000250539.1	competence type IV pilus minor pilin ComGF	Machinery gene
Q7625_RS10035 (Q7625_10020)	comGE/cglE	1960335..1960637 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
Q7625_RS10040 (Q7625_10025)	comGD/cglD	1960600..1961004 (-)	405	WP_000588030.1	competence type IV pilus minor pilin ComGD	Machinery gene
Q7625_RS10045 (Q7625_10030)	comGC/cglC	1960997..1961323 (-)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
Q7625_RS10050 (Q7625_10035)	comGB/cglB	1961325..1962341 (-)	1017	WP_078134418.1	competence type IV pilus assembly protein ComGB	Machinery gene
Q7625_RS10055 (Q7625_10040)	comGA/cglA/cilD	1962289..1963230 (-)	942	WP_000249573.1	competence type IV pilus ATPase ComGA	Machinery gene
Q7625_RS10060 (Q7625_10045)	-	1963306..1963671 (-)	366	WP_000286415.1	DUF1033 family protein	-
Q7625_RS10065 (Q7625_10050)	-	1963822..1964880 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17851.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=863992 Q7625_RS10030 WP_000250539.1 1959911..1960372(-) (comGF/cglF) [Streptococcus pneumoniae strain 2016C10-332]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=863992 Q7625_RS10030 WP_000250539.1 1959911..1960372(-) (comGF/cglF) [Streptococcus pneumoniae strain 2016C10-332]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae D39	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae R6	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae TIGR4	94.118	100	0.941
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915