Detailed information NTG0863783

Bioinformatically predicted

Overview

• Name: comB
• Type: Regulator
• Locus tag: Q7627_RS00370
• Genome accession: NZ_CP131706
• Coordinates: 60794..62143 (+)
• Length: 449 a.a.
• NCBI ID: WP_000801603.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 2018N21-288
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 55794..67143

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7627_RS00350 (Q7627_00350)	-	56701..57183 (+)	483	WP_001232094.1	stage II sporulation protein M	-
Q7627_RS00355 (Q7627_00355)	-	57180..57776 (+)	597	WP_000687787.1	ATP-binding cassette domain-containing protein	-
Q7627_RS00360 (Q7627_00360)	-	57757..58248 (+)	492	WP_000671990.1	hypothetical protein	-
Q7627_RS00365 (Q7627_00365)	comA	58628..60781 (+)	2154	WP_000668299.1	peptide cleavage/export ABC transporter ComA	Regulator
Q7627_RS00370 (Q7627_00370)	comB	60794..62143 (+)	1350	WP_000801603.1	competence pheromone export protein ComB	Regulator
Q7627_RS00375 (Q7627_00375)	purC	62313..63020 (+)	708	WP_000043304.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
Q7627_RS00380	-	63022..63165 (+)	144	WP_050167432.1	hypothetical protein	-
Q7627_RS00385 (Q7627_00380)	-	63222..66947 (+)	3726	WP_000361164.1	phosphoribosylformylglycinamidine synthase	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 49629.51 Da
• Isoelectric Point: 5.3895

>NTDB_id=863783 Q7627_RS00370 WP_000801603.1 60794..62143(+) (comB) [Streptococcus pneumoniae strain 2018N21-288]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATIEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide

• Length: 1350 bp

>NTDB_id=863783 Q7627_RS00370 WP_000801603.1 60794..62143(+) (comB) [Streptococcus pneumoniae strain 2018N21-288]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAGAAGGAGATGAGTTTGTCCACTAGAGCTACTATCG
AACCCAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTAGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATGGAAACAGGTGCTTCCTTGGCCAGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACATTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCCTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCAACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATAGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB	Streptococcus pneumoniae TIGR4	98.886	100	0.989
comB	Streptococcus pneumoniae Rx1	98.664	100	0.987
comB	Streptococcus pneumoniae D39	98.664	100	0.987
comB	Streptococcus pneumoniae R6	98.664	100	0.987
comB	Streptococcus mitis SK321	94.878	100	0.949
comB	Streptococcus mitis NCTC 12261	94.432	100	0.944
comB	Streptococcus gordonii str. Challis substr. CH1	55.111	100	0.552