Detailed information NTG0863327

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: Q7642_RS13820
• Genome accession: NZ_CP131652
• Coordinates: 2785444..2786331 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143414.1
• Uniprot ID: A0A6B0AX73
• Organism: Staphylococcus aureus strain 2008S01-206
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2780444..2791331

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7642_RS13790 (Q7642_13780)	-	2780451..2780539 (+)	89	Protein_2674	hypothetical protein	-
Q7642_RS13795 (Q7642_13785)	-	2780647..2781144 (-)	498	WP_001065267.1	glutathione peroxidase	-
Q7642_RS13800 (Q7642_13790)	-	2781154..2781414 (-)	261	WP_072468805.1	hypothetical protein	-
Q7642_RS13805 (Q7642_13795)	-	2781796..2781909 (-)	114	WP_078065515.1	hypothetical protein	-
Q7642_RS13810 (Q7642_13800)	-	2782584..2784584 (-)	2001	WP_000776728.1	ABC transporter permease	-
Q7642_RS13815 (Q7642_13805)	-	2784581..2785336 (-)	756	WP_000923762.1	ABC transporter ATP-binding protein	-
Q7642_RS13820 (Q7642_13810)	braS	2785444..2786331 (-)	888	WP_000143414.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
Q7642_RS13825 (Q7642_13815)	braR	2786342..2787007 (-)	666	WP_000697882.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
Q7642_RS13830 (Q7642_13820)	-	2787033..2787233 (-)	201	WP_000604724.1	hypothetical protein	-
Q7642_RS13835 (Q7642_13825)	-	2787431..2788855 (+)	1425	WP_031874997.1	alkaline phosphatase	-
Q7642_RS13840 (Q7642_13830)	-	2788925..2789035 (+)	111	WP_001791296.1	hypothetical protein	-
Q7642_RS13845 (Q7642_13835)	-	2789138..2789593 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
Q7642_RS13850 (Q7642_13840)	-	2789837..2790598 (-)	762	WP_000323454.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34073.33 Da
• Isoelectric Point: 5.6141

>NTDB_id=863327 Q7642_RS13820 WP_000143414.1 2785444..2786331(-) (braS) [Staphylococcus aureus strain 2008S01-206]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKDDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSTGIGLFIVKQISNHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=863327 Q7642_RS13820 WP_000143414.1 2785444..2786331(-) (braS) [Staphylococcus aureus strain 2008S01-206]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAGATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATAAACAATATTATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGAATCGGTATTAGTGAGGCAGACTTACCTAAA
ATATTCGACAAAGGTTATTCGGGGTATAATGGACAACGTCAAAGTAATTCAACTGGGATTGGCTTATTTATTGTAAAGCA
AATTTCAAATCACACTAATCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A6B0AX73

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.305	100	0.983