Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   WBI56_RS20690 Genome accession   NZ_CP147492
Coordinates   4008459..4009661 (-) Length   400 a.a.
NCBI ID   WP_038828029.1    Uniprot ID   -
Organism   Bacillus subtilis strain MC4-2     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4003459..4014661
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WBI56_RS20665 (WBI56_20665) rocE 4003573..4004976 (-) 1404 WP_003242721.1 amino acid permease -
  WBI56_RS20670 (WBI56_20670) rocD 4005199..4006404 (-) 1206 WP_321541390.1 ornithine aminotransferase -
  WBI56_RS20675 (WBI56_20675) rocR 4006645..4008030 (+) 1386 WP_338731808.1 arginine utilization regulatory protein RocR -
  WBI56_RS20680 (WBI56_20680) - 4008012..4008194 (-) 183 Protein_4018 ATP-binding protein -
  WBI56_RS20685 (WBI56_20685) - 4008311..4008439 (-) 129 WP_003242634.1 hypothetical protein -
  WBI56_RS20690 (WBI56_20690) htrA 4008459..4009661 (-) 1203 WP_038828029.1 serine protease HtrC Regulator
  WBI56_RS20695 (WBI56_20695) vicX 4009743..4010537 (-) 795 WP_003242676.1 MBL fold metallo-hydrolase Regulator
  WBI56_RS20700 (WBI56_20700) walI 4010559..4011401 (-) 843 WP_003244037.1 WalRK two-component regulatory system regulator WalI -
  WBI56_RS20705 (WBI56_20705) walH 4011388..4012755 (-) 1368 WP_041850604.1 WalRK two-component regulatory system regulator WalH -
  WBI56_RS20710 (WBI56_20710) walK 4012745..4014580 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42784.51 Da        Isoelectric Point: 5.3354

>NTDB_id=859445 WBI56_RS20690 WP_038828029.1 4008459..4009661(-) (htrA) [Bacillus subtilis strain MC4-2]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGRVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=859445 WBI56_RS20690 WP_038828029.1 4008459..4009661(-) (htrA) [Bacillus subtilis strain MC4-2]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAGATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATTCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAGGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCCTCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCGCTAAGTGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGGAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

Peptidase family M50 (Peptidase_M50)

(183-395)

PDZ domain (PDZ_2)

(295-392)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.542

100

0.417
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.152

82.5

0.373
  htrA Streptococcus pneumoniae D39

45.152

82.5

0.373
  htrA Streptococcus pneumoniae Rx1

45.152

82.5

0.373
  htrA Streptococcus pneumoniae R6

45.152

82.5

0.373