Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   STYK_RS08175 Genome accession   NZ_AP024523
Coordinates   1615279..1617180 (-) Length   633 a.a.
NCBI ID   WP_261804861.1    Uniprot ID   -
Organism   Streptococcus toyakuensis strain TP1632     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1610279..1622180
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STYK_RS08150 (STYK_15610) - 1610419..1611384 (+) 966 WP_261804859.1 LacI family DNA-binding transcriptional regulator -
  STYK_RS08155 (STYK_15620) - 1611421..1612695 (-) 1275 WP_261804860.1 hydroxymethylglutaryl-CoA reductase, degradative -
  STYK_RS08160 (STYK_15630) - 1612695..1613867 (-) 1173 WP_045612596.1 hydroxymethylglutaryl-CoA synthase -
  STYK_RS08165 (STYK_15640) - 1613981..1614430 (-) 450 WP_033686494.1 threonine/serine exporter family protein -
  STYK_RS08170 (STYK_15650) - 1614432..1615190 (-) 759 WP_045612174.1 threonine/serine exporter family protein -
  STYK_RS08175 (STYK_15660) stkP 1615279..1617180 (-) 1902 WP_261804861.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  STYK_RS08180 (STYK_15670) - 1617177..1617917 (-) 741 WP_261804862.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  STYK_RS08185 (STYK_15680) rsmB 1617932..1619245 (-) 1314 WP_261804863.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  STYK_RS08190 (STYK_15690) fmt 1619238..1620173 (-) 936 WP_261804864.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 633 a.a.        Molecular weight: 69174.51 Da        Isoelectric Point: 9.4944

>NTDB_id=85758 STYK_RS08175 WP_261804861.1 1615279..1617180(-) (stkP) [Streptococcus toyakuensis strain TP1632]
MIQIGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHHPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSSLSYNRRNEPKLVFNDTTKADTKTLPKVPQSTLTSIPKVQTQSPKPQTA
KPSQQASEDNYATKPVKKRKFRVRYMILLASIVLVAASLIWILSRTPATIAIPNVAGQTVAEAKETLKKANFEIGDEKSE
ASEKVEEGRIIRTDPDAGTGRKEGTKINLVVSSGKQSFQLSNYIGRKSTDVIAELKQKKVPENLIKIEEEESSESEEGTV
LRQSPSAGTTYDLSKASTITLTIAKKVTSVAMPSYIGSSLEFTKNNLVQIVGIKEANIEVVEVTTAPSGTAEGTVVEQSP
RAGEKVDLNKTRIKISIYKPKTPPSTSSSAPAQRGNQGSTTTPSQGNQQGNQRGDTHSTNQSSSEGSHENSRN

Nucleotide


Download         Length: 1902 bp        

>NTDB_id=85758 STYK_RS08175 WP_261804861.1 1615279..1617180(-) (stkP) [Streptococcus toyakuensis strain TP1632]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTATCAAACAAATTGGTCGAGGAGGCATGGCAGATGTATA
CTTGGCCAAGGATTTGATTCTAGACGGGGAAGAAGTGGCAGTAAAGGTCCTGAGGACCAACTACCAAACAGATCCCATTG
CAGTGGCTCGTTTTCAGCGTGAAGCGAGAGCCATGGCAGATCTGGACCATCCTCATATCGTTCGGATTACAGATATTGGT
GAGGAAGACGGTCAACAGTACTTAGCTATGGAGTACGTAGCAGGACTTGACCTCAAACGCTATATCAAGGAACACCATCC
TCTTTCAAATGAAGAAGCGGTCCGAATCATGGGACAAATCCTCTTGGCTATGCGCTTAGCCCATACTAGAGGCATTGTTC
ACCGCGATTTGAAACCTCAAAATATCCTCTTGACACCAGATGGGACTGCCAAAGTCACAGATTTTGGGATTGCGGTAGCC
TTTGCTGAGACGAGTCTGACTCAGACCAACTCTATGCTGGGCTCGGTTCATTACTTGTCACCAGAGCAGGCGCGTGGTTC
TAAAGCGACTGTACAGAGTGATATCTATGCCATGGGGATCATCTTTTATGAGATGTTGACAGGACATATCCCTTACGATG
GGGATAGTGCAGTGACCATCGCCCTCCAGCATTTCCAAAAACCATTGCCATCGGTTATAGCTGAGAATCCATCTGTGCCT
CAGGCTTTAGAGAATGTTGTCATCAAGGCAACTGCCAAGAAATTGACAGATCGTTATCAGTCAGTTGCAGAGATGTATGT
GGACTTGTCTAGTAGTTTGTCTTATAATCGTCGCAATGAGCCTAAATTGGTGTTTAATGATACCACTAAGGCTGACACCA
AGACTCTTCCTAAAGTTCCACAAAGTACCTTGACTTCGATTCCTAAGGTGCAAACACAAAGTCCAAAGCCACAGACTGCG
AAGCCGAGTCAACAGGCTTCAGAGGACAATTACGCAACCAAGCCTGTTAAGAAACGGAAATTTAGAGTTCGCTATATGAT
TTTGTTGGCCAGCATTGTATTGGTGGCAGCTTCTCTTATTTGGATACTATCCAGAACTCCTGCAACCATTGCCATTCCAA
ATGTGGCAGGTCAGACAGTGGCGGAAGCCAAGGAAACCCTCAAGAAAGCCAATTTTGAGATTGGCGATGAGAAATCAGAG
GCTAGTGAAAAGGTGGAAGAAGGGCGGATTATCCGTACAGATCCTGACGCTGGAACTGGTCGAAAAGAAGGAACGAAAAT
CAATTTGGTTGTCTCATCAGGTAAGCAATCTTTCCAATTGAGCAATTATATCGGCCGTAAATCGACCGATGTTATCGCAG
AACTCAAGCAGAAGAAGGTACCTGAAAATCTCATCAAGATAGAGGAAGAAGAATCAAGCGAGAGTGAAGAAGGAACAGTT
CTTAGACAGAGCCCGTCAGCTGGAACAACTTATGATTTGAGTAAGGCCTCAACAATCACTTTAACTATTGCTAAGAAAGT
AACCAGCGTTGCTATGCCAAGTTATATAGGATCTAGTCTTGAATTTACTAAAAATAATCTCGTTCAAATTGTCGGTATTA
AAGAAGCCAACATTGAAGTTGTAGAAGTTACCACAGCTCCTTCCGGAACTGCTGAAGGTACCGTTGTTGAACAGAGTCCA
AGAGCGGGTGAAAAGGTAGATTTGAATAAGACACGCATCAAGATTTCAATTTACAAACCGAAAACACCGCCGTCAACATC
ATCATCAGCACCAGCCCAACGTGGAAACCAAGGTTCTACTACAACACCAAGTCAGGGGAACCAGCAAGGAAATCAACGAG
GAGATACTCATTCTACTAATCAATCAAGTAGTGAGGGAAGCCACGAAAATTCACGTAATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(371-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

80.375

92.575

0.744
  stkP Streptococcus pneumoniae D39

80.034

92.575

0.741
  stkP Streptococcus pneumoniae R6

80.034

92.575

0.741
  stkP Streptococcus pneumoniae Rx1

79.863

92.575

0.739
  stkP/pknB Streptococcus salivarius strain HSISS4

54.701

92.417

0.506
  pknB Streptococcus mutans UA159

55.095

91.469

0.504

Multiple sequence alignment