Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   STYK_RS03870 Genome accession   NZ_AP024523
Coordinates   742360..743100 (+) Length   246 a.a.
NCBI ID   WP_261805278.1    Uniprot ID   -
Organism   Streptococcus toyakuensis strain TP1632     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 737360..748100
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STYK_RS03850 (STYK_07060) - 737442..738545 (+) 1104 WP_261805275.1 glycosyltransferase -
  STYK_RS03855 (STYK_07070) - 738547..739533 (+) 987 WP_261805276.1 glycosyltransferase family 2 protein -
  STYK_RS03860 (STYK_07080) - 739549..741018 (+) 1470 WP_261805277.1 O-antigen polysaccharide polymerase Wzy family protein -
  STYK_RS03865 (STYK_07090) - 741011..742045 (+) 1035 WP_084923949.1 prephenate dehydratase -
  STYK_RS03870 (STYK_07100) mecA 742360..743100 (+) 741 WP_261805278.1 adaptor protein MecA Regulator
  STYK_RS03875 (STYK_07110) - 743252..744538 (+) 1287 WP_261805279.1 homoserine dehydrogenase -
  STYK_RS03880 (STYK_07120) thrB 744540..745409 (+) 870 WP_261805280.1 homoserine kinase -
  STYK_RS03885 (STYK_07130) msrB 745508..746446 (+) 939 WP_084923943.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28624.45 Da        Isoelectric Point: 4.0372

>NTDB_id=85737 STYK_RS03870 WP_261805278.1 742360..743100(+) (mecA) [Streptococcus toyakuensis strain TP1632]
MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPESFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLSDLPDMEELAQMSPDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQDEQEVEGKKKEPYIYYILSF
SKLADLVSFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDSDISRSVLQEYGQVLMNHDAVL
NLQKIG

Nucleotide


Download         Length: 741 bp        

>NTDB_id=85737 STYK_RS03870 WP_261805278.1 742360..743100(+) (mecA) [Streptococcus toyakuensis strain TP1632]
ATGAAAATGAAACAAATCAGTGATACAACTTTAAAAATCACGATGTCTTTAGAAGATTTGATGGATCGAGGAATGGAGAT
TGCTGACTTTCTCGTTCCTCAAGAAAAAACAGAAGAGTTTTTTTATGCCATCTTGGATGAGTTAGAGATGCCTGAGAGCT
TTTTGGATACAGGCATGTTGAGCTTCCGTGTGACTCCAAAACCTGATAAGGTAGATGTCTTTGTAACCAAATCAAAGATT
GACCAAAATCTAGATTTTGAAGACTTATCGGATTTACCAGATATGGAAGAATTAGCCCAAATGTCGCCAGATGAATTTAT
CAAAACCTTGGAAAAAAGCATCGCAGACAAAACTAAGGATGATATTGAAGCGATTCAATCTCTAGAGCAAGTAGAAGCCA
AGGAAGAAGAGCAGGAGCAGGATGAACAAGAAGTTGAAGGCAAGAAGAAAGAGCCTTACATCTACTACATCCTTTCTTTT
TCTAAGTTGGCTGATTTGGTGTCTTTTGCCAAGACAGTGACTTTTGAGATGGAAACTTCTGAACTCTACAAGATGAATGA
GCGCTATTATTTGACTATTTTAGTGGATATTGAAAATCATCCAAGTCCATATCCAGCTTGGCTCTTGGCACGTATGCGCG
AGTTTGCAGACGATAGTGATATCAGTCGCTCAGTCTTGCAGGAGTATGGTCAAGTCTTGATGAATCACGATGCAGTGCTC
AATCTGCAAAAGATTGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

96.341

100

0.963
  mecA Streptococcus pneumoniae D39

96.341

100

0.963
  mecA Streptococcus pneumoniae R6

96.341

100

0.963
  mecA Streptococcus pneumoniae TIGR4

95.935

100

0.959
  mecA Streptococcus mutans UA159

49.187

100

0.492
  mecA Streptococcus thermophilus LMD-9

46.988

100

0.476
  mecA Streptococcus thermophilus LMG 18311

46.586

100

0.472

Multiple sequence alignment