Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   QZN16_RS05540 Genome accession   NZ_CP129876
Coordinates   1063403..1064083 (-) Length   226 a.a.
NCBI ID   WP_000590620.1    Uniprot ID   A0AAV3JNX7
Organism   Streptococcus agalactiae strain NEM316     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1058403..1069083
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QZN16_RS05505 - 1058478..1058705 (-) 228 WP_000368981.1 hypothetical protein -
  QZN16_RS05510 - 1058921..1059250 (-) 330 WP_000806219.1 hypothetical protein -
  QZN16_RS05515 - 1059261..1059755 (-) 495 WP_000620669.1 hypothetical protein -
  QZN16_RS05520 - 1059792..1059980 (-) 189 WP_001161739.1 hypothetical protein -
  QZN16_RS05525 ffh 1060102..1061667 (-) 1566 WP_000863589.1 signal recognition particle protein -
  QZN16_RS05530 - 1061685..1062017 (-) 333 WP_000402075.1 putative DNA-binding protein -
  QZN16_RS05535 ciaH 1062106..1063419 (-) 1314 WP_000042576.1 HAMP domain-containing sensor histidine kinase Regulator
  QZN16_RS05540 ciaR 1063403..1064083 (-) 681 WP_000590620.1 response regulator transcription factor Regulator
  QZN16_RS05545 - 1064245..1066794 (-) 2550 WP_000859383.1 M1 family metallopeptidase -
  QZN16_RS05550 phoU 1066940..1067593 (-) 654 WP_000946330.1 phosphate signaling complex protein PhoU -
  QZN16_RS05555 pstB 1067627..1068385 (-) 759 WP_000193363.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 25852.63 Da        Isoelectric Point: 4.2507

>NTDB_id=856053 QZN16_RS05540 WP_000590620.1 1063403..1064083(-) (ciaR) [Streptococcus agalactiae strain NEM316]
MIKILLIEDDLSLSNSVFDFLDDFADVMQIFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTA
KESIDDKGQGFDLGADDYLTKPFYLEELKMRIQALLKRSGKFNDNSLIYGDIRVDMSTNSTFVNQTEVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKVRKKLKGTLFSENLQTLRSVGYILKHVETD

Nucleotide


Download         Length: 681 bp        

>NTDB_id=856053 QZN16_RS05540 WP_000590620.1 1063403..1064083(-) (ciaR) [Streptococcus agalactiae strain NEM316]
ATGATAAAAATTTTATTAATTGAAGATGACTTGAGTCTTTCCAATTCCGTTTTTGATTTCCTTGATGACTTTGCCGATGT
CATGCAAATTTTTGATGGAGAAGAGGGTCTTTACGAAGCCGAAAGTGGAGTCTATGATCTGATTCTTCTAGATCTCATGT
TACCTGAAAAAAACGGCTTCCAAGTGTTGAAAGAGCTACGTGAAAAAGGTATTACAACCCCTGTATTAATAATGACCGCT
AAAGAAAGCATTGATGATAAGGGACAAGGTTTCGACTTAGGTGCTGATGATTATCTAACAAAACCTTTTTACCTAGAAGA
ACTAAAAATGCGAATTCAGGCTCTTTTAAAGCGTTCTGGAAAATTTAATGATAACAGCCTAATTTATGGTGATATTCGCG
TAGACATGTCTACTAACTCAACCTTTGTTAATCAAACAGAAGTTGAGCTCTTAGGTAAAGAGTTTGATCTTTTAGTCTAT
TTCCTTCAAAATCAAAATGTTATCTTACCGAAATCTCAAATCTTTGATCGTATTTGGGGATTTGATAGTGATACAACGAT
TTCAGTTGTAGAAGTCTATGTCTCTAAGGTTCGGAAAAAATTAAAAGGAACACTTTTTTCAGAAAACCTTCAAACTTTGC
GTAGTGTAGGATATATTTTAAAGCATGTCGAAACCGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae TIGR4

88.393

99.115

0.876
  ciaR Streptococcus pneumoniae D39

88.393

99.115

0.876
  ciaR Streptococcus pneumoniae R6

88.393

99.115

0.876
  ciaR Streptococcus pneumoniae Rx1

88.393

99.115

0.876
  ciaR Streptococcus mutans UA159

88.688

97.788

0.867
  vicR Streptococcus mutans UA159

35.193

100

0.363
  covR Lactococcus lactis subsp. lactis strain DGCC12653

36.607

99.115

0.363