Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   LLWG2_RS11595 Genome accession   NZ_CP129660
Coordinates   2238397..2239620 (+) Length   407 a.a.
NCBI ID   WP_396420758.1    Uniprot ID   -
Organism   Lactococcus cremoris strain Wg2     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2233397..2244620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLWG2_RS11570 (LLWG2_11620) - 2234512..2235315 (-) 804 WP_011677190.1 phosphatidate cytidylyltransferase -
  LLWG2_RS11575 (LLWG2_11625) - 2235315..2236049 (-) 735 WP_021164970.1 isoprenyl transferase -
  LLWG2_RS11580 (LLWG2_11630) yajC 2236399..2236731 (-) 333 WP_011677192.1 preprotein translocase subunit YajC -
  LLWG2_RS11585 (LLWG2_11635) - 2236826..2237524 (-) 699 Protein_2256 DNA alkylation repair protein -
  LLWG2_RS11590 (LLWG2_11640) rlmH 2237542..2238021 (-) 480 WP_021164969.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  LLWG2_RS11595 (LLWG2_11645) htrA 2238397..2239620 (+) 1224 WP_396420758.1 S1C family serine protease Regulator
  LLWG2_RS11600 (LLWG2_11650) - 2239742..2240740 (+) 999 WP_021164967.1 glycosyltransferase family 4 protein -
  LLWG2_RS11605 (LLWG2_11655) - 2240878..2242218 (+) 1341 WP_021164966.1 glycosyltransferase family 4 protein -
  LLWG2_RS11610 (LLWG2_11660) - 2242325..2242549 (+) 225 WP_011677198.1 YkuJ family protein -
  LLWG2_RS11615 (LLWG2_11665) - 2242693..2243697 (+) 1005 WP_021164965.1 hypothetical protein -
  LLWG2_RS11620 (LLWG2_11670) - 2243754..2244506 (-) 753 WP_021164964.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 41601.05 Da        Isoelectric Point: 5.3802

>NTDB_id=854840 LLWG2_RS11595 WP_396420758.1 2238397..2239620(+) (htrA) [Lactococcus cremoris strain Wg2]
MAKANIGKLLLTGVVGGAIALGGSAIYQSTTNQLGNANRSNTTSTKVSNVSVNVNTDVTSAIKKVSNSVVSVMNYQKQNS
QSDFSSIFGGNSGSSSANDSLQLSSEGSGVIYKKSGGDAYVVTNYHVIAGNSSLDVLLSGGQKVKATVVGYDEYTDLAVL
KISSDHVKDVATFADSSKLTIGEPAIAVGSPLGSQFSNTATEGILSATSRQVTLTQENGQTTSINAIQTDAAINPGNSGG
ALINIEGQVIGITQSKITTTEDGSTSVEGLGFAIPSNDVVNIINKLETDGKISRPALGIRMVDLSQLSTNDSSQLKLPSS
VTGGLVVYSVQAGLPAATAGLKAGDVITKVGDTAVTSSTDLQSALYSHNINDTVKVTYYRDGKSATANVKLSKSTSDLET
NSSSSSN

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=854840 LLWG2_RS11595 WP_396420758.1 2238397..2239620(+) (htrA) [Lactococcus cremoris strain Wg2]
ATGGCAAAAGCTAATATAGGAAAATTGCTATTAACCGGTGTTGTGGGTGGAGCTATCGCACTCGGAGGAAGCGCAATTTA
TCAAAGCACTACAAACCAACTAGGAAATGCTAACCGCTCAAATACAACTAGCACAAAGGTTAGTAATGTTTCGGTAAATG
TCAATACCGATGTCACCTCTGCAATTAAAAAAGTTTCAAATTCTGTCGTTTCTGTTATGAATTATCAAAAACAGAATTCA
CAAAGTGATTTTAGTTCAATTTTTGGTGGAAATAGCGGCTCAAGTTCAGCTAATGACAGCTTGCAACTTTCCAGTGAGGG
TTCTGGTGTTATTTATAAAAAATCTGGTGGAGATGCTTACGTGGTCACTAACTATCACGTTATTGCTGGAAATAGTTCCC
TCGATGTTTTACTTTCTGGTGGGCAAAAAGTTAAAGCCACAGTTGTTGGTTATGATGAATACACTGACCTTGCCGTTCTT
AAAATCAGCTCTGACCATGTTAAAGACGTGGCAACTTTCGCTGATTCAAGCAAGTTAACTATTGGTGAACCAGCTATTGC
AGTCGGCTCACCTTTAGGTAGCCAGTTTTCTAATACTGCAACCGAAGGAATTCTGTCTGCAACAAGTCGTCAAGTCACTT
TGACTCAAGAAAATGGTCAAACAACAAGTATCAATGCGATTCAAACGGATGCTGCCATTAACCCGGGTAACTCAGGTGGA
GCCTTGATTAATATTGAAGGTCAAGTGATTGGTATTACTCAAAGTAAAATCACAACGACCGAAGATGGTTCTACCTCTGT
GGAAGGTTTAGGTTTTGCTATCCCATCTAATGATGTGGTAAACATCATTAATAAACTTGAAACTGATGGTAAGATTTCAC
GTCCTGCCTTAGGTATTCGTATGGTTGACCTATCTCAATTATCAACAAATGATAGTTCTCAACTGAAATTACCTAGCAGC
GTAACTGGTGGATTGGTTGTCTACTCTGTTCAAGCGGGTCTTCCTGCTGCCACAGCTGGTCTGAAAGCTGGCGATGTGAT
AACGAAGGTGGGAGATACCGCCGTTACTTCATCAACAGACTTACAAAGTGCTCTTTACTCACACAATATTAATGATACTG
TGAAAGTCACCTACTACCGTGATGGTAAATCAGCCACAGCAAATGTTAAACTCTCTAAATCAACAAGCGATTTAGAAACA
AATAGTTCATCTTCTTCTAATTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(226-395)

PDZ domain (PDZ_2)

(295-391)

Trypsin-like peptidase domain (Trypsin_2)

(107-252)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

55.614

94.103

0.523
  htrA Streptococcus gordonii str. Challis substr. CH1

54.615

95.823

0.523
  htrA Streptococcus pneumoniae Rx1

57.849

84.521

0.489
  htrA Streptococcus pneumoniae D39

57.849

84.521

0.489
  htrA Streptococcus pneumoniae R6

57.849

84.521

0.489
  htrA Streptococcus pneumoniae TIGR4

57.849

84.521

0.489
  htrA Streptococcus mutans UA159

52.846

90.663

0.479