Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   QY866_RS08660 Genome accession   NZ_CP129530
Coordinates   1718369..1720525 (-) Length   718 a.a.
NCBI ID   WP_116843679.1    Uniprot ID   A0A385AFB1
Organism   Latilactobacillus sakei strain A1262     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1713369..1725525
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QY866_RS08630 (QY866_08620) tdcB 1713986..1715026 (-) 1041 WP_004271086.1 bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB -
  QY866_RS08635 (QY866_08625) - 1715242..1715574 (+) 333 WP_004271076.1 hypothetical protein -
  QY866_RS08640 (QY866_08630) - 1715620..1715817 (-) 198 WP_004271075.1 hypothetical protein -
  QY866_RS08645 (QY866_08635) - 1715918..1716244 (-) 327 WP_004271083.1 bacteriocin immunity protein -
  QY866_RS08650 (QY866_08640) - 1716572..1716775 (-) 204 WP_076790047.1 Blp family class II bacteriocin -
  QY866_RS08655 (QY866_08645) - 1716978..1718354 (-) 1377 WP_099947277.1 HlyD family secretion protein -
  QY866_RS08660 (QY866_08650) comA 1718369..1720525 (-) 2157 WP_116843679.1 peptide cleavage/export ABC transporter Regulator
  QY866_RS08665 (QY866_08655) - 1720876..1721172 (-) 297 WP_076787949.1 bacteriocin immunity protein -
  QY866_RS08670 (QY866_08660) - 1721266..1721451 (-) 186 WP_004271264.1 leucocin A/sakacin P family class II bacteriocin -
  QY866_RS08675 (QY866_08665) - 1721598..1722344 (-) 747 WP_004271265.1 response regulator transcription factor -
  QY866_RS08680 (QY866_08670) - 1722346..1723512 (-) 1167 WP_251945224.1 GHKL domain-containing protein -
  QY866_RS08685 (QY866_08675) - 1723711..1723821 (-) 111 WP_254681820.1 bacteriocin -
  QY866_RS08690 (QY866_08680) - 1724001..1724348 (+) 348 WP_099947274.1 bacteriocin immunity protein -
  QY866_RS08695 (QY866_08685) - 1724409..1724816 (-) 408 WP_099947273.1 DUF3021 domain-containing protein -
  QY866_RS08700 (QY866_08690) - 1724822..1725274 (-) 453 WP_011374263.1 LytTR family DNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 718 a.a.        Molecular weight: 80204.37 Da        Isoelectric Point: 5.8513

>NTDB_id=854113 QY866_RS08660 WP_116843679.1 1718369..1720525(-) (comA) [Latilactobacillus sakei strain A1262]
MIDRKIYIPQVDEMDCGVAALAMILKHYGSSASLAYLRNEAKTDLEGTTALGLVKTAENLGFETKAIQADMSLFEVADLP
FPFIAHVLKNGELLHYYVVLGIKKDAIIIADPDPTVGIAKMTQSQFKSEWTGVALFIAPKPSYQPVKQQTKASLFSFVPT
LMQQKRLVINITLAALLITIISILGSYFLQTVIDTYIPNNMQSTLAIVAIGLIIFYGFQSIFTYAQNFLLAVLGQRLSIE
IILSYLRHVFELPMSFFATRKTGEIISRFNDANKIIDALASAIISIFLDITVVVIMGIILIIQNTTLFWLTLAVIPIYIA
VITLFAKPFEKLNQKEMESNAVLNSAIIEDLHGIETIKALTSESERYQKIDTAFVDYLKKSFDYVKADTLQQAIKLFVQL
GLNVFVLWVGAILVTHNELSIGQLMTYNALLAYFVNPLQNIINLQTKLQSARVANNRLNEVYLVDSEFKTERPIKSESQL
VGPIELQNVSYQYGYGQRVLESISLKIEPNEKLTIVGMSGSGKSTLVKLLVNFFEPTEGKVLFNQQDTQTIDKKTLRQFV
NYIAQTPYIFSGSIWDNLKLGNRPGITQADIMHACELAEIKNDIEKMPLQFETLLDEDGNTLSGGQKQRLTIARALLSPA
RVLIFDESTSGLDTITEGLLVDHLMALEERTIIFIAHRLAIAKKTNNILVLENGSVVETGTHDALVDTQGRYYQLLNH

Nucleotide


Download         Length: 2157 bp        

>NTDB_id=854113 QY866_RS08660 WP_116843679.1 1718369..1720525(-) (comA) [Latilactobacillus sakei strain A1262]
ATGATAGATCGTAAAATTTATATACCACAAGTAGATGAAATGGATTGTGGCGTAGCAGCTTTAGCGATGATTCTTAAACA
TTATGGTTCTTCAGCTTCGCTGGCTTATTTACGTAATGAGGCTAAAACTGATTTAGAAGGAACAACGGCGCTTGGACTAG
TGAAGACAGCTGAGAATTTAGGTTTCGAAACGAAGGCGATTCAAGCTGATATGAGTTTGTTTGAAGTCGCAGATTTACCA
TTTCCTTTTATTGCACATGTTCTAAAAAATGGCGAGCTATTACATTATTATGTTGTACTAGGGATAAAAAAAGATGCCAT
TATAATCGCCGATCCTGATCCAACAGTGGGCATCGCTAAGATGACGCAATCACAGTTTAAATCGGAATGGACGGGCGTTG
CATTATTTATTGCTCCAAAACCGAGCTATCAACCAGTTAAGCAGCAAACAAAAGCGAGTTTATTTTCATTTGTTCCAACT
TTGATGCAGCAAAAGCGATTGGTAATTAATATTACTTTGGCGGCGCTACTCATAACCATTATTAGTATTCTAGGATCTTA
TTTCTTACAGACTGTCATTGATACCTATATCCCAAATAACATGCAGAGCACGCTGGCGATTGTTGCAATTGGTTTAATTA
TCTTTTATGGCTTCCAGTCAATCTTTACATATGCTCAAAATTTTTTATTGGCGGTTTTAGGACAGCGGTTATCAATTGAG
ATTATTTTAAGTTACTTAAGACATGTTTTTGAATTACCAATGTCTTTTTTTGCAACACGTAAAACAGGTGAAATAATTTC
ACGATTTAATGACGCGAATAAAATTATTGATGCGCTAGCAAGCGCAATTATTTCAATTTTTTTAGATATTACAGTCGTTG
TTATTATGGGGATTATTCTGATCATTCAAAATACAACTTTATTCTGGTTAACCTTAGCAGTGATTCCAATCTATATTGCC
GTGATTACTTTATTTGCAAAACCTTTTGAAAAATTAAATCAAAAGGAAATGGAAAGTAATGCAGTATTGAATTCGGCGAT
CATTGAAGATTTACATGGCATTGAAACGATTAAAGCGTTAACTAGTGAAAGTGAACGATATCAAAAAATAGATACAGCAT
TTGTTGATTATCTGAAGAAGAGTTTTGACTATGTAAAAGCTGATACATTGCAACAAGCAATTAAGTTGTTTGTCCAATTA
GGGCTGAATGTCTTTGTGCTGTGGGTAGGCGCTATTTTAGTCACGCATAACGAGTTATCAATTGGGCAATTGATGACCTA
CAATGCCTTGCTGGCGTATTTTGTAAATCCGTTACAGAATATCATCAATTTACAGACTAAGTTACAGAGCGCGAGGGTAG
CCAATAATCGGTTGAATGAAGTTTATCTGGTTGATTCTGAGTTCAAGACAGAACGACCAATTAAATCCGAGTCACAGTTG
GTAGGCCCAATTGAGTTACAAAATGTGAGTTACCAATATGGTTATGGGCAGAGAGTGCTTGAATCGATTAGTTTAAAGAT
TGAGCCGAATGAAAAATTAACAATTGTGGGCATGAGCGGTTCGGGGAAATCAACATTGGTTAAGTTACTCGTTAATTTTT
TTGAACCAACGGAGGGAAAGGTTCTTTTTAATCAACAAGATACACAGACAATTGATAAAAAGACATTGCGGCAGTTTGTT
AACTATATTGCACAGACACCGTACATTTTCTCAGGAAGTATTTGGGATAATCTTAAGTTAGGTAATCGGCCAGGAATCAC
ACAAGCGGACATCATGCATGCGTGTGAGCTAGCAGAGATAAAGAATGATATTGAAAAAATGCCGCTCCAATTTGAAACAT
TATTGGATGAAGATGGAAACACATTGTCAGGTGGTCAAAAACAGCGATTAACAATTGCGCGAGCACTATTATCACCAGCT
CGGGTACTAATTTTTGATGAGTCTACTAGTGGGTTAGATACGATAACAGAGGGGCTATTAGTTGATCATCTAATGGCGTT
AGAAGAAAGAACAATCATTTTCATAGCGCATCGTTTAGCGATTGCTAAGAAAACGAACAATATTCTTGTTTTAGAAAATG
GTAGTGTTGTTGAAACTGGGACACATGATGCGTTGGTGGATACACAAGGGCGATATTACCAATTGCTCAATCATTAG

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(500-650)

Peptidase C39 family (Peptidase_C39)

(7-141)

ABC transporter transmembrane region (ABC_membrane)

(168-438)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A385AFB1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

58.824

99.443

0.585
  comA Streptococcus pneumoniae TIGR4

58.263

99.443

0.579
  comA Streptococcus mitis SK321

58.263

99.443

0.579
  comA Streptococcus pneumoniae R6

58.123

99.443

0.578
  comA Streptococcus pneumoniae Rx1

58.123

99.443

0.578
  comA Streptococcus pneumoniae D39

58.123

99.443

0.578
  comA Streptococcus gordonii str. Challis substr. CH1

56.723

99.443

0.564
  comA/nlmT Streptococcus mutans UA159

54.366

98.886

0.538