Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   QYM01_RS05025 Genome accession   NZ_CP129527
Coordinates   1046028..1046765 (+) Length   245 a.a.
NCBI ID   WP_012515591.1    Uniprot ID   B4U2V5
Organism   Streptococcus equi subsp. zooepidemicus strain BJ-1     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1041028..1051765
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QYM01_RS04995 (QYM01_04995) - 1041470..1042375 (-) 906 WP_012677986.1 diacylglycerol kinase family protein -
  QYM01_RS05000 (QYM01_05000) - 1042485..1043135 (-) 651 WP_012515586.1 hemolysin III family protein -
  QYM01_RS05005 (QYM01_05005) - 1043119..1043574 (-) 456 WP_043983552.1 DUF1836 domain-containing protein -
  QYM01_RS05010 (QYM01_05010) - 1043834..1044589 (+) 756 WP_206158623.1 class I SAM-dependent methyltransferase -
  QYM01_RS05015 (QYM01_05015) - 1044617..1044955 (+) 339 WP_231141375.1 cupin domain-containing protein -
  QYM01_RS05020 (QYM01_05020) - 1044957..1045262 (+) 306 WP_037578256.1 hypothetical protein -
  QYM01_RS05025 (QYM01_05025) comE/blpR 1046028..1046765 (+) 738 WP_012515591.1 response regulator transcription factor Regulator
  QYM01_RS05030 (QYM01_05030) - 1047137..1047367 (+) 231 WP_043038961.1 Blp family class II bacteriocin -
  QYM01_RS05035 (QYM01_05035) - 1048160..1049011 (+) 852 WP_301899117.1 thioredoxin family protein -
  QYM01_RS05040 (QYM01_05040) - 1049394..1049591 (+) 198 WP_231149475.1 lactococcin 972 family bacteriocin -
  QYM01_RS05045 (QYM01_05045) - 1049696..1051711 (+) 2016 WP_301899118.1 DUF1430 domain-containing protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28894.28 Da        Isoelectric Point: 7.8796

>NTDB_id=853993 QYM01_RS05025 WP_012515591.1 1046028..1046765(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain BJ-1]
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLLANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKMKALEAS
IKALH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=853993 QYM01_RS05025 WP_012515591.1 1046028..1046765(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain BJ-1]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAACAGTTTAGGCTTGAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACTTGTGATCGTTTTGAAGTTTATGGAAAGCCCTACCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATAGTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATCAGAAAGCGTGAC
CCTTATGCCCTCATTGTTTTTGTCACGACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATTGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGTAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATTGAGACCTCTAGTACCCCTCACAAGTTGATTTTGCATTCTCAAAACGAGCGAATAGAATTTTACGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATTCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAATGGGCAGTCTTGCATGGTTTCAAGACTAAAAATGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGCATTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-240)

Response regulator receiver domain (Response_reg)

(18-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B4U2V5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.719

98.776

0.531
  comE/comE1 Streptococcus equinus JB1

45.455

98.776

0.449
  comE/comE2 Streptococcus equinus JB1

36.885

99.592

0.367