NTDB

Overview

Name	comE/blpR	Type	Regulator
Locus tag	V6U68_RS09155	Genome accession	NZ_CP145866
Coordinates	1974965..1975708 (-)	Length	247 a.a.
NCBI ID	WP_070655754.1	Uniprot ID	-
Organism	Streptococcus salivarius strain KSS9
Function	activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1969965..1980708

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U68_RS09140 (V6U68_09120)	rnpA	1970688..1971023 (-)	336	WP_002891957.1	ribonuclease P protein component	-
V6U68_RS09145 (V6U68_09125)	argH	1971108..1972493 (-)	1386	WP_060971562.1	argininosuccinate lyase	-
V6U68_RS09150 (V6U68_09130)	-	1972820..1974019 (-)	1200	WP_410531668.1	argininosuccinate synthase	-
V6U68_RS09155 (V6U68_09135)	comE/blpR	1974965..1975708 (-)	744	WP_070655754.1	response regulator transcription factor	Regulator
V6U68_RS09160 (V6U68_09140)	-	1975710..1977026 (-)	1317	WP_107372389.1	GHKL domain-containing protein	-
V6U68_RS09165 (V6U68_09145)	-	1977050..1978330 (-)	1281	WP_410531669.1	hypothetical protein	-
V6U68_RS09170 (V6U68_09150)	-	1978352..1979242 (-)	891	WP_002891966.1	hypothetical protein	-
V6U68_RS09175 (V6U68_09155)	-	1979298..1980605 (-)	1308	WP_037600068.1	GHKL domain-containing protein	-

Sequence

Protein

Download Length: 247 a.a. Molecular weight: 28550.85 Da Isoelectric Point: 6.7591

                                >NTDB_id=853889 V6U68_RS09155 WP_070655754.1 1974965..1975708(-) (comE/blpR) [Streptococcus salivarius strain KSS9]

MNIYILEDDLMQQTRISDIIRELVSEGTFSVRKLEVFSKPHKLLSSINEKGNHQVFLLDIDIDGERKKGLEVASEIRQQD

ANAVIIFVTTHSEFAPISFKYKVSALDFIDKTVSNAEFKQQLKQTLTFVNQKVGDVDDDEIFVFETAQSRIQVPMREIYY

FATAVTPHKVMLITKTERLEFYANLGDITSVNKKLFSCHRSFLVNLDNISRIDKTQLMIYFENGDSCPVSRLKMKALLKK

WSEVKEH

Nucleotide

Download Length: 744 bp

                                >NTDB_id=853889 V6U68_RS09155 WP_070655754.1 1974965..1975708(-) (comE/blpR) [Streptococcus salivarius strain KSS9]

ATGAATATATACATTTTAGAAGATGACTTAATGCAGCAAACACGTATTAGTGACATCATCCGAGAATTGGTTTCAGAGGG

CACGTTTTCCGTACGAAAACTTGAAGTTTTTTCTAAACCTCACAAACTATTGTCCAGTATCAACGAAAAAGGTAACCATC

AGGTTTTTCTTTTAGATATCGATATTGATGGTGAGCGAAAGAAGGGGCTAGAAGTCGCCTCAGAAATTCGTCAACAAGAT

GCTAATGCAGTTATTATTTTTGTAACAACTCACTCAGAGTTTGCACCGATCAGTTTTAAATACAAGGTTTCTGCACTAGA

TTTCATTGATAAGACAGTTTCTAATGCAGAGTTCAAACAACAACTAAAACAAACATTGACTTTTGTGAACCAAAAAGTTG

GAGATGTGGATGATGATGAGATATTTGTGTTTGAAACAGCGCAGTCTCGGATCCAAGTCCCTATGAGAGAGATTTATTAT

TTTGCGACTGCTGTGACACCTCATAAGGTGATGCTAATTACCAAAACAGAGCGTCTGGAGTTTTATGCCAATCTTGGAGA

TATTACTTCGGTAAATAAAAAACTTTTTTCTTGTCATCGCTCCTTTTTAGTTAATTTGGATAACATATCTCGTATTGATA

AGACTCAGTTGATGATTTATTTTGAAAATGGTGATTCTTGTCCAGTTTCACGTTTGAAAATGAAGGCTCTGCTTAAAAAA

TGGTCAGAGGTAAAAGAACATTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comE/blpR	Streptococcus mutans UA159	47.917	97.166	0.466
comE/comE2	Streptococcus equinus JB1	42.449	99.19	0.421
comE/comE1	Streptococcus equinus JB1	40.083	97.976	0.393
comE/comE2	Streptococcus gordonii strain NCTC7865	37.008	100	0.381
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	37.008	100	0.381

Detailed information NTG0853889