Detailed information NTG0853669

Bioinformatically predicted

Overview

• Name: comGB
• Type: Machinery gene
• Locus tag: V6U66_RS09940
• Genome accession: NZ_CP145864
• Coordinates: 2110752..2111852 (-)
• Length: 366 a.a.
• NCBI ID: WP_155214000.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS7
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2105752..2116852

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U66_RS09900 (V6U66_09880)	-	2106361..2106558 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
V6U66_RS09905 (V6U66_09885)	-	2106809..2108002 (-)	1194	WP_002885831.1	acetate kinase	-
V6U66_RS09910 (V6U66_09890)	comGH	2108059..2109015 (-)	957	WP_014632544.1	class I SAM-dependent methyltransferase	Machinery gene
V6U66_RS09915 (V6U66_09895)	comGG	2109060..2109377 (-)	318	WP_045001363.1	competence type IV pilus minor pilin ComGG	Machinery gene
V6U66_RS09920 (V6U66_09900)	comGF	2109355..2109792 (-)	438	WP_410534501.1	competence type IV pilus minor pilin ComGF	Machinery gene
V6U66_RS09925 (V6U66_09905)	comGE	2109779..2110009 (-)	231	WP_013991265.1	competence type IV pilus minor pilin ComGE	Machinery gene
V6U66_RS09930 (V6U66_09910)	comGD	2110041..2110469 (-)	429	WP_014632541.1	competence type IV pilus minor pilin ComGD	Machinery gene
V6U66_RS09935 (V6U66_09915)	comGC	2110429..2110755 (-)	327	WP_070576715.1	competence type IV pilus major pilin ComGC	Machinery gene
V6U66_RS09940 (V6U66_09920)	comGB	2110752..2111852 (-)	1101	WP_155214000.1	competence type IV pilus assembly protein ComGB	Machinery gene
V6U66_RS09945 (V6U66_09925)	comGA	2111734..2112675 (-)	942	WP_155214001.1	competence type IV pilus ATPase ComGA	Machinery gene
V6U66_RS09950 (V6U66_09930)	-	2112755..2113117 (-)	363	WP_002887019.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41627.57 Da
• Isoelectric Point: 10.0357

>NTDB_id=853669 V6U66_RS09940 WP_155214000.1 2110752..2111852(-) (comGB) [Streptococcus salivarius strain KSS7]
MPVKISKAIRQPAGTSSWKAWFNKDISLKGISKGKKLKINQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KASLMRGDRLDQMFASVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKDNWAVQLVQIFPQLFFVSLCGLLVLSLIHYLWVKHQPALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVSLMQEQKSKLFRELGADLEEALMLGQSFPDRIATHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFVIVAVVIVMIYAAMLLPMYQNMEGMIS

Nucleotide

• Length: 1101 bp

>NTDB_id=853669 V6U66_RS09940 WP_155214000.1 2110752..2111852(-) (comGB) [Streptococcus salivarius strain KSS7]
TTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAGCAGTTGGAAGGCTTGGTTCAACAAGGATATCTC
ACTGAAGGGGATATCAAAGGGGAAAAAATTAAAGATTAATCAGCAAGTCAAGGTTATCCAGCTTTTCAAACAACTTCTAA
AGGCAGGGTTTACTTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTGAAAGAATCGTCATTATCTCTTATG
AAAGCAAGCTTAATGCGAGGCGACAGGCTAGACCAGATGTTTGCGTCAGTGGGTTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAATCTTCTAGGGAGTTTAACCAAGATTGAAACCTACATGCTTCGCATGACTAAGGTTC
GTAAGAAACTCATGGAGGTAGCGACCTACCCTATCCTACTCCTGGGTTTCCTGATTCTGATTATGTTAGGACTTAAAAAT
TATCTTTTACCTCAACTGTTAGAGGGTGATGGTAAGGATAATTGGGCTGTACAGTTGGTTCAAATCTTTCCCCAGCTCTT
CTTTGTGAGTTTGTGTGGACTTCTTGTATTAAGCTTAATTCATTATCTATGGGTCAAACACCAGCCAGCCCTTGTCTTTT
ATCGACGAATGGCAAAAATCCCTTTCATAGGCCAAACTGTCAGGCTATATACGACCGCCTATTATGCTAGGGAATGGGGA
AATCTCTTAGGACAAGGCGTTGACCTGTTAGACTTGGTTTCTCTTATGCAAGAGCAAAAGTCCAAGCTCTTTCGTGAGCT
GGGGGCTGATTTAGAAGAGGCCTTGATGCTAGGACAGAGTTTTCCTGACCGTATTGCTACTCACCCTTTTTTCACTAAGG
AACTATCCTTGATTATTGCTTATGGAGAGGCTAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATATCATGA

Domains

Predicted by InterProScan.

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB	Streptococcus mutans UA140	55.394	93.716	0.519
comGB	Streptococcus mutans UA159	55.394	93.716	0.519
comGB	Streptococcus gordonii str. Challis substr. CH1	51.02	93.716	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.144	94.809	0.475
comGB/cglB	Streptococcus mitis SK321	49.704	92.35	0.459
comGB/cglB	Streptococcus pneumoniae Rx1	49.408	92.35	0.456
comGB/cglB	Streptococcus pneumoniae D39	49.408	92.35	0.456
comGB/cglB	Streptococcus pneumoniae R6	49.408	92.35	0.456
comGB/cglB	Streptococcus pneumoniae TIGR4	49.408	92.35	0.456
comGB	Lactococcus lactis subsp. cremoris KW2	44.985	89.891	0.404