Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   V6U66_RS09680 Genome accession   NZ_CP145864
Coordinates   2068757..2069500 (-) Length   247 a.a.
NCBI ID   WP_002886967.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS7     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2063757..2074500
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U66_RS09665 (V6U66_09645) argH 2063812..2065197 (-) 1386 WP_037601513.1 argininosuccinate lyase -
  V6U66_RS09670 (V6U66_09650) - 2065524..2066723 (-) 1200 WP_002885646.1 argininosuccinate synthase -
  V6U66_RS09675 (V6U66_09655) - 2067724..2068605 (-) 882 WP_227834288.1 IS30 family transposase -
  V6U66_RS09680 (V6U66_09660) comE/blpR 2068757..2069500 (-) 744 WP_002886967.1 response regulator transcription factor Regulator
  V6U66_RS09685 (V6U66_09665) - 2069502..2070818 (-) 1317 WP_045769399.1 GHKL domain-containing protein -
  V6U66_RS09690 (V6U66_09670) - 2070842..2072122 (-) 1281 WP_013991230.1 hypothetical protein -
  V6U66_RS09695 (V6U66_09675) - 2072144..2073034 (-) 891 WP_013991231.1 hypothetical protein -
  V6U66_RS09700 (V6U66_09680) - 2073089..2074396 (-) 1308 WP_410534490.1 GHKL domain-containing protein -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28533.89 Da        Isoelectric Point: 7.0533

>NTDB_id=853658 V6U66_RS09680 WP_002886967.1 2068757..2069500(-) (comE/blpR) [Streptococcus salivarius strain KSS7]
MNIYILEDDLMQQTRISDIIRELVSEGAFSVRKLEVFSKPHKLLSSINEKGNHQIFLLDIDIDGNRKKGLEVASEIRQQD
ANAVIIFVTTHSEFAPISFKYKVSALDFIEKTVSNVEFKQQLKQTLTFVNQKIGDVDDDEMFVFETAQSRIQVPMRDIYY
FATAATPHKVMLITKTERLEFYANLGDITSVNKILFSCHRSFLVNLDNIARIDKTQLMIYFENGDSCPVSRLKMKALLKK
WSEVRNH

Nucleotide


Download         Length: 744 bp        

>NTDB_id=853658 V6U66_RS09680 WP_002886967.1 2068757..2069500(-) (comE/blpR) [Streptococcus salivarius strain KSS7]
ATGAATATATATATTTTAGAAGATGATTTGATGCAACAAACACGTATTAGTGATATCATCAGAGAATTGGTTTCAGAGGG
TGCGTTTTCTGTACGAAAACTTGAAGTTTTTTCTAAACCACATAAACTATTGTCCAGCATCAACGAGAAGGGGAACCATC
AGATTTTTCTTTTGGATATTGATATTGATGGCAATCGAAAGAAGGGGTTAGAAGTTGCCTCTGAAATTCGTCAACAAGAT
GCTAATGCGGTTATTATTTTTGTAACAACTCACTCAGAATTTGCTCCAATTAGTTTTAAGTATAAGGTTTCCGCACTTGA
TTTTATTGAAAAGACAGTCTCTAATGTGGAATTCAAACAACAATTGAAACAAACCTTGACTTTTGTAAATCAAAAAATTG
GAGATGTGGACGATGATGAGATGTTTGTGTTTGAAACTGCTCAGTCTAGAATACAAGTTCCGATGCGAGATATTTATTAT
TTTGCGACAGCTGCAACTCCTCATAAGGTAATGTTAATTACTAAAACAGAGCGCCTGGAGTTTTATGCTAATCTTGGAGA
TATTACTTCGGTGAATAAAATACTCTTTTCATGTCACCGCTCCTTTTTAGTTAATCTGGATAATATTGCCCGTATTGATA
AGACGCAACTGATGATTTATTTTGAGAATGGTGATTCATGTCCGGTTTCTCGCTTGAAAATGAAGGCCCTACTTAAAAAA
TGGTCAGAGGTAAGAAATCATTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

47.083

97.166

0.457
  comE/comE2 Streptococcus equinus JB1

41.633

99.19

0.413
  comE/comE1 Streptococcus equinus JB1

39.669

97.976

0.389
  comE/comE2 Streptococcus gordonii strain NCTC7865

36.929

97.571

0.36
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

36.929

97.571

0.36