Detailed information NTG0085336

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: J3989_RS02075
• Genome accession: NZ_AP024489
• Coordinates: 431751..432938 (+)
• Length: 395 a.a.
• NCBI ID: WP_196962999.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain NIID777
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 426751..437938

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J3989_RS02060 (NMNIID777_03800)	-	427671..428270 (+)	600	WP_101126719.1	DUF4390 domain-containing protein	-
J3989_RS02065 (NMNIID777_03810)	-	428270..430390 (+)	2121	WP_101126720.1	PAS domain-containing sensor histidine kinase	-
J3989_RS02070 (NMNIID777_03820)	-	430383..431660 (+)	1278	WP_002237528.1	sigma-54 dependent transcriptional regulator	-
J3989_RS02075 (NMNIID777_03830)	dprA	431751..432938 (+)	1188	WP_196962999.1	DNA-processing protein DprA	Machinery gene
J3989_RS02080 (NMNIID777_03840)	-	432964..433425 (+)	462	WP_002215351.1	DUF494 family protein	-
J3989_RS02085 (NMNIID777_03850)	topA	433497..435803 (+)	2307	WP_002234458.1	type I DNA topoisomerase	-
J3989_RS02090 (NMNIID777_03860)	-	435876..436571 (-)	696	WP_002216227.1	hypothetical protein	-
J3989_RS02095 (NMNIID777_03870)	-	436591..437142 (-)	552	WP_101115886.1	hypothetical protein	-
J3989_RS02100 (NMNIID777_03880)	-	437260..437637 (+)	378	WP_002233408.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 395 a.a.
• Molecular weight: 42164.35 Da
• Isoelectric Point: 6.3108

>NTDB_id=85336 J3989_RS02075 WP_196962999.1 431751..432938(+) (dprA) [Neisseria meningitidis strain NIID777]
MTEDERFAWLQLAFTPYIGAESFLLLMRRFGSAQNALSAPAEQVAALIRHKQALEAWRNAEKRALARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGRALGEKGIPVVSGMASGIDT
AAHQGALQAEGGTIAVWGTGIDRIYPPSNKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLVECLDDILNECPGLLQNTGASSYSINKDTPDTGRRAVQT
AYAPPPAAKMPSEAAAGGTAHGGILDKMGFDPVHPDVLAEQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1188 bp

>NTDB_id=85336 J3989_RS02075 WP_196962999.1 431751..432938(+) (dprA) [Neisseria meningitidis strain NIID777]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGTTTCCTGCTGCTGAT
GCGCCGTTTCGGCAGCGCGCAAAATGCCCTGTCCGCACCGGCGGAACAGGTGGCGGCACTGATACGGCACAAACAGGCGC
TTGAGGCTTGGCGCAATGCGGAAAAACGCGCTCTGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGCCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAGGGCGTTGGGTGAAAAAGGCATTCCCGTTGTGTCGGGTATGGCTTCGGGCATCGATACC
GCCGCCCATCAGGGTGCGTTGCAGGCAGAAGGCGGCACCATCGCTGTGTGGGGGACGGGCATAGACCGCATTTATCCGCC
GTCCAATAAAAACCTTGCCTATGAAATCGCCGAAAAAGGGCTGATTGTCAGCGAGTTCCCCATCGGTACGCGGCCGTATG
CCGGCAACTTTCCGCGCCGCAACCGCCTGATTGCCGCGCTGTCGCAGGTTACGCTGGTGGTTGAAGCTGCGTTGGAATCC
GGTTCGCTGATTACCGCCGGCTTGGCGGCAGAAATGGGGCGCGAAGTGATGGCGGTACCCGGTTCGATAGACAATCCGCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGCGCGAAATTGGTGGAATGCCTGGACGACATCCTGAACGAATGCCCGG
GGCTATTGCAAAATACGGGTGCTTCATCATATTCTATAAATAAGGATACGCCCGACACGGGACGCCGCGCCGTTCAGACG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCCGTCTGAAGCGGCGGCAGGCGGCACAGCCCACGGCGGCATACTGGATAA
AATGGGTTTCGACCCCGTCCATCCCGACGTGCTTGCCGAGCAGCTTGCTATGCCTGCCGCAGATTTGTATGCCGCACTGT
TGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (79-283)

• DprA winged helix domain (DprA_WH) (332-388)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria gonorrhoeae strain FA1090	96.456	100	0.965
dprA	Neisseria gonorrhoeae MS11	96.203	100	0.962
dprA	Neisseria meningitidis strain C311	91.94	100	0.924
dprA	Neisseria meningitidis MC58	91.94	100	0.924
dprA	Vibrio cholerae strain A1552	38.287	100	0.385