Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   V6U64_RS01060 Genome accession   NZ_CP145862
Coordinates   195562..196305 (+) Length   247 a.a.
NCBI ID   WP_002885796.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS4     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 190562..201305
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U64_RS01040 (V6U64_01040) - 190660..191967 (+) 1308 WP_073687793.1 GHKL domain-containing protein -
  V6U64_RS01045 (V6U64_01045) - 192028..192918 (+) 891 WP_002885882.1 hypothetical protein -
  V6U64_RS01050 (V6U64_01050) - 192940..194220 (+) 1281 WP_118188973.1 hypothetical protein -
  V6U64_RS01055 (V6U64_01055) - 194274..195560 (+) 1287 WP_272157236.1 GHKL domain-containing protein -
  V6U64_RS01060 (V6U64_01060) comE/blpR 195562..196305 (+) 744 WP_002885796.1 response regulator transcription factor Regulator
  V6U64_RS01065 (V6U64_01065) - 197252..198451 (+) 1200 WP_002885646.1 argininosuccinate synthase -
  V6U64_RS01070 (V6U64_01070) argH 198778..200163 (+) 1386 WP_037601513.1 argininosuccinate lyase -
  V6U64_RS01075 (V6U64_01075) rnpA 200248..200583 (+) 336 WP_002891957.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28536.83 Da        Isoelectric Point: 6.7589

>NTDB_id=853351 V6U64_RS01060 WP_002885796.1 195562..196305(+) (comE/blpR) [Streptococcus salivarius strain KSS4]
MNIYILEDDLMQQTRISDIIRELVSEGTFSVRKLEVFSKPHKLLSSINEKGNHQVFLLDIDIDGERKKGLEVASEIRQQD
ANAVIIFVTTHSEFAPISFKYKVSALDFIDKTVSNAEFKQQLKQTLTFVNQKVGDVDDDEIFVFETAQSRIQVPMRDIYY
FATAVTPHKVMLITKTERLEFYANLGDITSVNKKLFSCHRSFLVNLDNISRIDKTQLMIYFENGDSCPVSRLKMKALLKK
WSEVKEH

Nucleotide


Download         Length: 744 bp        

>NTDB_id=853351 V6U64_RS01060 WP_002885796.1 195562..196305(+) (comE/blpR) [Streptococcus salivarius strain KSS4]
ATGAATATATACATTTTAGAAGATGACTTAATGCAGCAAACACGCATTAGCGACATCATCCGAGAATTGGTTTCAGAGGG
CACGTTTTCCGTACGAAAACTTGAAGTTTTTTCTAAACCTCACAAACTATTGTCCAGTATCAACGAGAAGGGCAACCATC
AGGTTTTCCTTTTAGATATCGATATTGATGGTGAGCGAAAGAAGGGGCTAGAAGTCGCCTCAGAAATTCGCCAACAAGAT
GCTAATGCAGTTATTATTTTTGTAACAACTCACTCAGAGTTTGCACCGATCAGTTTTAAATACAAGGTTTCTGCACTAGA
TTTCATTGATAAGACAGTTTCTAATGCAGAATTCAAACAACAACTAAAACAAACATTGACTTTTGTGAACCAAAAAGTTG
GAGATGTGGATGATGATGAGATATTTGTGTTTGAAACCGCTCAGTCTCGGATCCAAGTCCCTATGAGAGATATTTATTAT
TTTGCGACTGCTGTGACACCTCATAAGGTGATGCTAATTACCAAAACAGAGCGTCTGGAGTTTTATGCCAATCTTGGAGA
TATTACTTCGGTAAATAAAAAACTCTTTTCTTGTCATCGCTCCTTTTTAGTTAATTTGGATAACATATCTCGTATTGATA
AGACTCAGTTGATGATTTACTTTGAAAATGGCGATTCTTGTCCAGTTTCACGTTTGAAAATGAAGGCCCTGCTTAAAAAA
TGGTCAGAGGTAAAAGAACATTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

47.5

97.166

0.462
  comE/comE2 Streptococcus equinus JB1

42.857

99.19

0.425
  comE/comE1 Streptococcus equinus JB1

40.496

97.976

0.397
  comE/comE2 Streptococcus gordonii strain NCTC7865

37.402

100

0.385
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

37.402

100

0.385