NTDB

Overview

Name	comE/blpR	Type	Regulator
Locus tag	V6U62_RS01020	Genome accession	NZ_CP145860
Coordinates	189373..190116 (+)	Length	247 a.a.
NCBI ID	WP_002885796.1	Uniprot ID	-
Organism	Streptococcus salivarius strain KSS2
Function	activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 184373..195116

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U62_RS01000 (V6U62_00995)	-	184472..185779 (+)	1308	WP_073687793.1	GHKL domain-containing protein	-
V6U62_RS01005 (V6U62_01000)	-	185839..186729 (+)	891	WP_022496040.1	hypothetical protein	-
V6U62_RS01010 (V6U62_01005)	-	186751..188031 (+)	1281	WP_022496039.1	hypothetical protein	-
V6U62_RS01015 (V6U62_01010)	-	188085..189371 (+)	1287	WP_272157236.1	GHKL domain-containing protein	-
V6U62_RS01020 (V6U62_01015)	comE/blpR	189373..190116 (+)	744	WP_002885796.1	response regulator transcription factor	Regulator
V6U62_RS01025 (V6U62_01020)	-	191063..192262 (+)	1200	WP_002885646.1	argininosuccinate synthase	-
V6U62_RS01030 (V6U62_01025)	argH	192589..193974 (+)	1386	WP_037601513.1	argininosuccinate lyase	-
V6U62_RS01035 (V6U62_01030)	rnpA	194059..194394 (+)	336	WP_002891957.1	ribonuclease P protein component	-

Sequence

Protein

Download Length: 247 a.a. Molecular weight: 28536.83 Da Isoelectric Point: 6.7589

                                >NTDB_id=853134 V6U62_RS01020 WP_002885796.1 189373..190116(+) (comE/blpR) [Streptococcus salivarius strain KSS2]

MNIYILEDDLMQQTRISDIIRELVSEGTFSVRKLEVFSKPHKLLSSINEKGNHQVFLLDIDIDGERKKGLEVASEIRQQD

ANAVIIFVTTHSEFAPISFKYKVSALDFIDKTVSNAEFKQQLKQTLTFVNQKVGDVDDDEIFVFETAQSRIQVPMRDIYY

FATAVTPHKVMLITKTERLEFYANLGDITSVNKKLFSCHRSFLVNLDNISRIDKTQLMIYFENGDSCPVSRLKMKALLKK

WSEVKEH

Nucleotide

Download Length: 744 bp

                                >NTDB_id=853134 V6U62_RS01020 WP_002885796.1 189373..190116(+) (comE/blpR) [Streptococcus salivarius strain KSS2]

ATGAATATATACATTTTAGAAGATGACTTAATGCAGCAAACACGCATTAGCGACATCATCCGAGAATTGGTTTCAGAGGG

CACGTTTTCCGTACGAAAACTTGAAGTTTTTTCTAAACCTCACAAACTATTGTCCAGTATCAACGAGAAGGGCAACCATC

AGGTTTTCCTTTTAGATATCGATATTGATGGTGAGCGAAAGAAGGGGCTAGAAGTCGCCTCAGAAATTCGCCAACAAGAT

GCTAATGCAGTTATTATTTTTGTAACAACTCACTCAGAGTTTGCACCGATCAGTTTTAAATACAAGGTTTCTGCACTAGA

TTTCATTGATAAGACAGTTTCTAATGCAGAATTCAAACAACAACTAAAACAAACATTGACTTTTGTGAACCAAAAAGTTG

GAGATGTGGATGATGATGAGATATTTGTGTTTGAAACCGCTCAGTCTCGGATCCAAGTCCCTATGAGAGATATTTATTAT

TTTGCGACTGCTGTGACACCTCATAAGGTGATGCTAATTACCAAAACAGAGCGTCTGGAGTTTTATGCCAATCTTGGAGA

TATTACTTCGGTAAATAAAAAACTCTTTTCTTGTCATCGCTCCTTTTTAGTTAATTTGGATAACATATCTCGTATTGATA

AGACTCAGTTGATGATTTACTTTGAAAATGGCGATTCTTGTCCAGTTTCACGTTTGAAAATGAAGGCCCTGCTTAAAAAA

TGGTCAGAGGTAAAAGAACATTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comE/blpR	Streptococcus mutans UA159	47.5	97.166	0.462
comE/comE2	Streptococcus equinus JB1	42.857	99.19	0.425
comE/comE1	Streptococcus equinus JB1	40.496	97.976	0.397
comE/comE2	Streptococcus gordonii strain NCTC7865	37.402	100	0.385
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	37.402	100	0.385

Detailed information NTG0853134