Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   V6T26_RS00960 Genome accession   NZ_CP145858
Coordinates   170023..170766 (+) Length   247 a.a.
NCBI ID   WP_002885796.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS11     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 165023..175766
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6T26_RS00940 (V6T26_00940) - 165129..166436 (+) 1308 WP_037600068.1 GHKL domain-containing protein -
  V6T26_RS00945 (V6T26_00945) - 166492..167382 (+) 891 WP_002891966.1 hypothetical protein -
  V6T26_RS00950 (V6T26_00950) - 167404..168684 (+) 1281 WP_002891965.1 hypothetical protein -
  V6T26_RS00955 (V6T26_00955) - 168705..170021 (+) 1317 WP_145517097.1 GHKL domain-containing protein -
  V6T26_RS00960 (V6T26_00960) comE/blpR 170023..170766 (+) 744 WP_002885796.1 response regulator transcription factor Regulator
  V6T26_RS00965 (V6T26_00965) - 171709..172908 (+) 1200 WP_037598503.1 argininosuccinate synthase -
  V6T26_RS00970 (V6T26_00970) argH 173235..174620 (+) 1386 WP_002891959.1 argininosuccinate lyase -
  V6T26_RS00975 (V6T26_00975) rnpA 174705..175040 (+) 336 WP_037600055.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28536.83 Da        Isoelectric Point: 6.7589

>NTDB_id=853022 V6T26_RS00960 WP_002885796.1 170023..170766(+) (comE/blpR) [Streptococcus salivarius strain KSS11]
MNIYILEDDLMQQTRISDIIRELVSEGTFSVRKLEVFSKPHKLLSSINEKGNHQVFLLDIDIDGERKKGLEVASEIRQQD
ANAVIIFVTTHSEFAPISFKYKVSALDFIDKTVSNAEFKQQLKQTLTFVNQKVGDVDDDEIFVFETAQSRIQVPMRDIYY
FATAVTPHKVMLITKTERLEFYANLGDITSVNKKLFSCHRSFLVNLDNISRIDKTQLMIYFENGDSCPVSRLKMKALLKK
WSEVKEH

Nucleotide


Download         Length: 744 bp        

>NTDB_id=853022 V6T26_RS00960 WP_002885796.1 170023..170766(+) (comE/blpR) [Streptococcus salivarius strain KSS11]
ATGAATATTTACATTTTAGAAGATGACTTAATGCAGCAAACACGTATTAGTGACATCATCAGAGAATTGGTTTCAGAGGG
CACGTTTTCCGTACGAAAACTTGAAGTTTTTTCTAAACCCCACAAACTATTGTCCAGTATCAACGAGAAGGGTAACCATC
AGGTTTTCCTTTTGGATATTGATATTGATGGTGAGCGAAAGAAGGGGCTAGAAGTCGCCTCAGAAATTCGCCAACAAGAT
GCTAATGCGGTTATTATTTTTGTGACAACTCACTCAGAGTTTGCACCGATTAGTTTTAAATACAAGGTTTCTGCGTTAGA
TTTTATTGATAAGACAGTTTCTAATGCAGAGTTCAAACAACAACTAAAACAAACATTGACTTTTGTAAATCAAAAAGTTG
GAGATGTGGATGATGATGAGATATTTGTGTTTGAAACAGCACAGTCTCGAATCCAAGTCCCTATGAGAGATATTTATTAT
TTTGCGACTGCGGTAACACCTCATAAGGTGATGCTGATTACTAAAACAGAGCGTTTGGAGTTTTATGCCAATCTTGGAGA
TATTACTTCGGTGAATAAAAAACTCTTTTCTTGTCATCGCTCGTTTTTAGTTAATTTGGATAATATTTCTCGTATTGATA
AGACTCAGTTGATGATTTACTTTGAAAATGGCGATTCTTGTCCAGTTTCACGTTTGAAAATGAAGGCCTTGCTTAAAAAA
TGGTCAGAGGTAAAAGAACATTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

47.5

97.166

0.462
  comE/comE2 Streptococcus equinus JB1

42.857

99.19

0.425
  comE/comE1 Streptococcus equinus JB1

40.496

97.976

0.397
  comE/comE2 Streptococcus gordonii strain NCTC7865

37.402

100

0.385
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

37.402

100

0.385