NTDB

Overview

Name	comE/blpR	Type	Regulator
Locus tag	V6T01_RS09260	Genome accession	NZ_CP145856
Coordinates	1991654..1992397 (-)	Length	247 a.a.
NCBI ID	WP_002885796.1	Uniprot ID	-
Organism	Streptococcus salivarius strain KSS1
Function	activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1986654..1997397

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6T01_RS09245 (V6T01_09220)	rnpA	1987380..1987715 (-)	336	WP_037600055.1	ribonuclease P protein component	-
V6T01_RS09250 (V6T01_09225)	argH	1987800..1989185 (-)	1386	WP_002891959.1	argininosuccinate lyase	-
V6T01_RS09255 (V6T01_09230)	-	1989512..1990711 (-)	1200	WP_037598503.1	argininosuccinate synthase	-
V6T01_RS09260 (V6T01_09235)	comE/blpR	1991654..1992397 (-)	744	WP_002885796.1	response regulator transcription factor	Regulator
V6T01_RS09265 (V6T01_09240)	-	1992399..1993715 (-)	1317	WP_145517097.1	GHKL domain-containing protein	-
V6T01_RS09270 (V6T01_09245)	-	1993736..1995016 (-)	1281	WP_002891965.1	hypothetical protein	-
V6T01_RS09275 (V6T01_09250)	-	1995038..1995928 (-)	891	WP_002891966.1	hypothetical protein	-
V6T01_RS09280 (V6T01_09255)	-	1995984..1997291 (-)	1308	WP_037600068.1	GHKL domain-containing protein	-

Sequence

Protein

Download Length: 247 a.a. Molecular weight: 28536.83 Da Isoelectric Point: 6.7589

                                >NTDB_id=852987 V6T01_RS09260 WP_002885796.1 1991654..1992397(-) (comE/blpR) [Streptococcus salivarius strain KSS1]

MNIYILEDDLMQQTRISDIIRELVSEGTFSVRKLEVFSKPHKLLSSINEKGNHQVFLLDIDIDGERKKGLEVASEIRQQD

ANAVIIFVTTHSEFAPISFKYKVSALDFIDKTVSNAEFKQQLKQTLTFVNQKVGDVDDDEIFVFETAQSRIQVPMRDIYY

FATAVTPHKVMLITKTERLEFYANLGDITSVNKKLFSCHRSFLVNLDNISRIDKTQLMIYFENGDSCPVSRLKMKALLKK

WSEVKEH

Nucleotide

Download Length: 744 bp

                                >NTDB_id=852987 V6T01_RS09260 WP_002885796.1 1991654..1992397(-) (comE/blpR) [Streptococcus salivarius strain KSS1]

ATGAATATTTACATTTTAGAAGATGACTTAATGCAGCAAACACGTATTAGTGACATCATCAGAGAATTGGTTTCAGAGGG

CACGTTTTCCGTACGAAAACTTGAAGTTTTTTCTAAACCCCACAAACTATTGTCCAGTATCAACGAGAAGGGTAACCATC

AGGTTTTCCTTTTGGATATTGATATTGATGGTGAGCGAAAGAAGGGGCTAGAAGTCGCCTCAGAAATTCGCCAACAAGAT

GCTAATGCGGTTATTATTTTTGTGACAACTCACTCAGAGTTTGCACCGATTAGTTTTAAATACAAGGTTTCTGCGTTAGA

TTTTATTGATAAGACAGTTTCTAATGCAGAGTTCAAACAACAACTAAAACAAACATTGACTTTTGTAAATCAAAAAGTTG

GAGATGTGGATGATGATGAGATATTTGTGTTTGAAACAGCACAGTCTCGAATCCAAGTCCCTATGAGAGATATTTATTAT

TTTGCGACTGCGGTAACACCTCATAAGGTGATGCTGATTACTAAAACAGAGCGTTTGGAGTTTTATGCCAATCTTGGAGA

TATTACTTCGGTGAATAAAAAACTCTTTTCTTGTCATCGCTCGTTTTTAGTTAATTTGGATAATATTTCTCGTATTGATA

AGACTCAGTTGATGATTTACTTTGAAAATGGCGATTCTTGTCCAGTTTCACGTTTGAAAATGAAGGCCTTGCTTAAAAAA

TGGTCAGAGGTAAAAGAACATTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comE/blpR	Streptococcus mutans UA159	47.5	97.166	0.462
comE/comE2	Streptococcus equinus JB1	42.857	99.19	0.425
comE/comE1	Streptococcus equinus JB1	40.496	97.976	0.397
comE/comE2	Streptococcus gordonii strain NCTC7865	37.402	100	0.385
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	37.402	100	0.385

Detailed information NTG0852987