Detailed information NTG0852238

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: QYR57_RS09940
• Genome accession: NZ_CP129327
• Coordinates: 2049501..2050703 (+)
• Length: 400 a.a.
• NCBI ID: WP_016356270.1
• Uniprot ID: -
• Organism: Streptococcus iniae strain Si 4-21
• Function: require for competence development (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	2048174..2049349	2049501..2050703	flank	152

Gene organization within MGE regions

Location: 2048174..2050703

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QYR57_RS09935 (QYR57_09945)	-	2048174..2049349 (+)	1176	WP_367561679.1	IS256 family transposase	-
QYR57_RS09940 (QYR57_09950)	htrA	2049501..2050703 (+)	1203	WP_016356270.1	S1C family serine protease	Regulator

Sequence

Protein

• Length: 400 a.a.
• Molecular weight: 42479.20 Da
• Isoelectric Point: 6.7483

>NTDB_id=852238 QYR57_RS09940 WP_016356270.1 2049501..2050703(+) (htrA) [Streptococcus iniae strain Si 4-21]
MSHFKNIYKLIWVLLAGFLGGFFAFIVINTFNQKTSTQETIISNPTKTSKVTYKNTTNTTKAVKVIQNAVVSVLNYQAVD
TNTSNPASQLFGQENDLKKDDGLSLFSEGSGVIYKKDDKSAYLVTNNHVIDGAKRIEILLADGSKVVGKLVGSDTYSDLA
VVKISADKIKSIGEFADSTKINVGEVAIAIGSPLGSEYANSVTEGIVSSLSRTVTLKNEEGQTVSTNALQTDAAINPGNS
GGPLINIEGQIIGINSSKISSGSNGGAVEGMGFAIPSNDVLKIINQLEGKGEVIRPALGISMVNLGDLSTNAISQLKIPK
DLTGGIVVASVKEGMPASGKLEQYDIITEINGKAVTTTSDLQSELYGHNIDDSIKITFYRGKDKKTDTIKLTKTTKDLEK

Nucleotide

• Length: 1203 bp

>NTDB_id=852238 QYR57_RS09940 WP_016356270.1 2049501..2050703(+) (htrA) [Streptococcus iniae strain Si 4-21]
ATGTCACATTTTAAAAATATATACAAATTAATTTGGGTTCTTTTGGCAGGCTTTTTAGGTGGTTTTTTTGCATTTATAGT
TATTAATACCTTTAATCAAAAAACTTCTACACAAGAGACAATTATTTCAAATCCTACTAAAACAAGTAAAGTAACTTATA
AAAACACAACTAATACAACTAAAGCGGTAAAGGTTATCCAAAATGCTGTTGTATCTGTGCTCAATTATCAAGCAGTTGAT
ACAAATACGTCAAATCCTGCAAGTCAACTTTTTGGACAAGAAAATGATTTAAAAAAAGATGACGGGCTATCTCTTTTTAG
TGAAGGATCTGGTGTCATTTATAAAAAAGATGATAAATCTGCTTATTTAGTAACAAATAATCATGTTATTGATGGTGCTA
AACGAATTGAAATTCTACTAGCTGATGGTTCTAAAGTTGTTGGAAAATTAGTTGGTTCTGATACTTATTCAGATTTAGCT
GTTGTTAAAATTTCAGCTGATAAAATTAAATCTATTGGAGAATTTGCTGACTCTACAAAAATAAATGTTGGTGAAGTTGC
AATTGCTATTGGTAGCCCACTGGGATCTGAATATGCTAATTCCGTAACAGAAGGTATTGTTTCAAGTCTTAGCAGAACAG
TTACTCTAAAAAATGAAGAAGGACAGACCGTTTCAACAAATGCTCTACAAACAGATGCGGCAATTAATCCTGGTAATTCA
GGTGGTCCATTAATCAATATTGAAGGGCAAATTATTGGGATTAATTCAAGTAAAATTTCTTCAGGTTCAAATGGAGGAGC
TGTCGAAGGAATGGGATTTGCAATTCCTTCCAATGACGTTCTTAAAATTATTAATCAACTTGAAGGAAAAGGAGAAGTGA
TTCGTCCTGCCTTAGGCATTTCAATGGTTAATCTTGGTGATCTGTCAACAAATGCAATTAGCCAATTAAAGATTCCAAAG
GACTTAACAGGTGGTATTGTTGTCGCATCTGTCAAAGAAGGGATGCCTGCTTCAGGAAAACTTGAGCAATACGATATTAT
TACAGAAATTAATGGCAAAGCTGTCACTACAACAAGTGATCTTCAAAGTGAATTATATGGACATAATATTGACGACTCAA
TCAAAATAACTTTCTATAGAGGAAAAGATAAGAAAACAGATACCATCAAACTAACAAAGACAACTAAAGATTTAGAAAAA
TAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (109-254)

• Peptidase family M50 (Peptidase_M50) (11-396)

• PDZ domain (PDZ_2) (296-391)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	62.025	98.75	0.612
htrA	Streptococcus mitis NCTC 12261	54.208	100	0.548
htrA	Streptococcus pneumoniae Rx1	53.96	100	0.545
htrA	Streptococcus pneumoniae D39	53.96	100	0.545
htrA	Streptococcus pneumoniae R6	53.96	100	0.545
htrA	Streptococcus pneumoniae TIGR4	53.96	100	0.545
htrA	Streptococcus gordonii str. Challis substr. CH1	54.386	99.75	0.543