Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   LLD17_RS12420 Genome accession   NZ_CP129182
Coordinates   2269633..2270856 (+) Length   407 a.a.
NCBI ID   WP_081196897.1    Uniprot ID   -
Organism   Lactococcus cremoris strain D.1.7     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2264633..2275856
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLD17_RS12395 (LLD17_12440) - 2265748..2266551 (-) 804 WP_011677190.1 phosphatidate cytidylyltransferase -
  LLD17_RS12400 (LLD17_12445) - 2266551..2267285 (-) 735 WP_081196896.1 isoprenyl transferase -
  LLD17_RS12405 (LLD17_12450) yajC 2267635..2267967 (-) 333 WP_011677192.1 preprotein translocase subunit YajC -
  LLD17_RS12410 (LLD17_12455) - 2268062..2268760 (-) 699 Protein_2277 DNA alkylation repair protein -
  LLD17_RS12415 (LLD17_12460) rlmH 2268778..2269257 (-) 480 WP_021164969.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  LLD17_RS12420 (LLD17_12465) htrA 2269633..2270856 (+) 1224 WP_081196897.1 S1C family serine protease Regulator
  LLD17_RS12425 (LLD17_12470) - 2270978..2271976 (+) 999 WP_021164967.1 glycosyltransferase family 4 protein -
  LLD17_RS12430 (LLD17_12475) - 2272114..2273454 (+) 1341 WP_014573350.1 glycosyltransferase family 4 protein -
  LLD17_RS12435 (LLD17_12480) - 2273561..2273785 (+) 225 WP_011677198.1 YkuJ family protein -
  LLD17_RS12440 (LLD17_12485) - 2273929..2274933 (+) 1005 WP_021164965.1 hypothetical protein -
  LLD17_RS12445 (LLD17_12490) - 2274990..2275742 (-) 753 WP_021164964.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 41645.14 Da        Isoelectric Point: 5.3802

>NTDB_id=851417 LLD17_RS12420 WP_081196897.1 2269633..2270856(+) (htrA) [Lactococcus cremoris strain D.1.7]
MAKANIGKLLLTGVVGGAIALGGSAIYQSTTNQLGNANRSNTTSTKVSNVSVNVNTDVTSAIKKVSNSVVSVMNYQKQNS
QSDFSSIFGGNSGSSSANDSLQLSSEGSGVIYKKSGGDAYVVTNYHVIAGNSFLDVLLSGGQKVKATVVGYDEYTDLAVL
KISSDHVKDVATFADSSKLTIGEPAIAVGSPLGSQFANTATEGILSATSRQVTLTQENGQTTSINAIQTDAAINPGNSGG
ALINIEGQVIGITQSKITTTEDGSTSVEGLGFAIPSNDVVNIINKLETDGKISRPALGIRMVDLSQLSTNDSSQLKLPSS
VTGGLVVYSVQAGLPAATAGLKAGDVITKVGDTAVTSSTDLQSALYSHNINDTVKVTYYRDGKSATANVKLSKSTSDLET
NSSSSSN

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=851417 LLD17_RS12420 WP_081196897.1 2269633..2270856(+) (htrA) [Lactococcus cremoris strain D.1.7]
ATGGCAAAAGCTAATATAGGAAAATTGCTATTAACCGGTGTTGTGGGTGGAGCTATCGCACTCGGAGGAAGCGCAATTTA
TCAAAGCACTACAAACCAACTAGGAAATGCTAACCGCTCAAATACAACTAGCACAAAGGTTAGTAATGTTTCGGTAAATG
TCAATACCGATGTCACCTCTGCAATTAAAAAAGTTTCAAATTCTGTCGTTTCTGTTATGAATTATCAAAAACAGAATTCA
CAAAGTGATTTTAGTTCAATTTTTGGTGGAAATAGCGGCTCAAGTTCAGCTAATGACAGCTTGCAACTTTCCAGTGAGGG
TTCTGGTGTTATTTATAAAAAATCTGGTGGAGATGCTTACGTGGTCACTAACTATCACGTTATTGCTGGAAATAGTTTCC
TCGATGTTTTACTTTCTGGTGGGCAAAAAGTTAAAGCCACAGTTGTTGGTTATGATGAATACACTGACCTTGCCGTTCTT
AAAATCAGCTCTGACCATGTTAAAGACGTGGCAACTTTCGCTGATTCAAGCAAGTTAACTATTGGTGAACCAGCTATTGC
AGTCGGCTCACCTTTAGGTAGCCAGTTTGCTAATACTGCAACCGAAGGAATTCTGTCTGCAACAAGTCGTCAAGTCACTT
TGACTCAAGAAAATGGTCAAACAACAAGTATCAATGCGATTCAAACGGATGCTGCCATTAACCCGGGTAACTCAGGTGGA
GCCTTGATTAATATTGAAGGTCAAGTGATTGGTATTACTCAAAGTAAAATCACAACGACCGAAGATGGTTCTACCTCTGT
GGAAGGTTTAGGTTTTGCTATCCCATCTAATGATGTGGTAAACATCATTAATAAACTTGAAACTGATGGTAAGATTTCAC
GTCCTGCCTTAGGTATTCGTATGGTTGACCTATCTCAATTATCAACAAATGATAGTTCTCAACTGAAATTACCTAGCAGC
GTAACTGGTGGATTGGTTGTCTACTCTGTTCAAGCGGGTCTTCCTGCTGCCACAGCTGGTCTGAAAGCTGGCGATGTGAT
AACGAAGGTGGGAGATACCGCCGTTACTTCATCAACAGACTTACAAAGTGCTCTTTACTCACACAATATTAATGATACTG
TGAAAGTCACCTACTACCGTGATGGTAAATCAGCCACAGCAAATGTTAAACTCTCTAAATCAACAAGCGATTTAGAAACA
AATAGTTCATCTTCTTCTAATTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(107-252)

Peptidase family M50 (Peptidase_M50)

(207-395)

PDZ domain (PDZ_2)

(295-391)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

55.875

94.103

0.526
  htrA Streptococcus gordonii str. Challis substr. CH1

54.872

95.823

0.526
  htrA Streptococcus pneumoniae Rx1

58.14

84.521

0.491
  htrA Streptococcus pneumoniae D39

58.14

84.521

0.491
  htrA Streptococcus pneumoniae R6

58.14

84.521

0.491
  htrA Streptococcus pneumoniae TIGR4

58.14

84.521

0.491
  htrA Streptococcus mutans UA159

53.117

90.663

0.482