Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   LC065_RS20425 Genome accession   NZ_CP129016
Coordinates   1261750..1262433 (-) Length   227 a.a.
NCBI ID   WP_371933413.1    Uniprot ID   -
Organism   Halobacillus litoralis strain SaN21-8     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1256750..1267433
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LC065_RS06470 (LC065_06470) - 1257280..1258737 (+) 1458 WP_226595025.1 sucrose-6-phosphate hydrolase -
  LC065_RS06475 (LC065_06475) - 1258819..1259301 (+) 483 WP_306163826.1 transcription repressor NadR -
  LC065_RS06480 (LC065_06480) cls 1259525..1260967 (+) 1443 WP_226595029.1 cardiolipin synthase -
  LC065_RS20425 htrA 1261750..1262433 (-) 684 WP_371933413.1 S1C family serine protease Regulator
  LC065_RS20430 - 1262445..1262900 (-) 456 WP_371933414.1 hypothetical protein -
  LC065_RS06490 (LC065_06490) - 1263093..1263779 (+) 687 WP_306163827.1 response regulator transcription factor -
  LC065_RS06495 (LC065_06495) - 1263776..1265107 (+) 1332 WP_226592959.1 HAMP domain-containing sensor histidine kinase -
  LC065_RS06500 (LC065_06500) - 1265173..1265694 (+) 522 WP_089653695.1 acyl-CoA thioesterase -
  LC065_RS06505 (LC065_06505) - 1265733..1266455 (-) 723 WP_226592957.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 24199.19 Da        Isoelectric Point: 3.9599

>NTDB_id=850574 LC065_RS20425 WP_371933413.1 1261750..1262433(-) (htrA) [Halobacillus litoralis strain SaN21-8]
MQKVAELGKASDVEVGQTAIAIGNPLGMEFAGSVTKGIVSGLNRNIPVDINGDQQPDWQTEVLQTDAAINPGNSGGALIN
LQGEVIGINSMKIAKAEVEGIGFSIPMDVAKPVIEDLETNGEVERPYMGVSLQDLNQIPNPVLQRELGLPEKVTEGVLVQ
GVEKGSPADEAGLEKYDVITAIDGNEIESLISLRQYLYNQAQDGDTAELEVYRDGKPTTVQITLTSR

Nucleotide


Download         Length: 684 bp        

>NTDB_id=850574 LC065_RS20425 WP_371933413.1 1261750..1262433(-) (htrA) [Halobacillus litoralis strain SaN21-8]
GTGCAAAAGGTTGCTGAATTAGGTAAAGCCAGTGACGTAGAGGTCGGGCAAACAGCCATTGCCATCGGTAACCCGCTGGG
CATGGAATTCGCAGGATCCGTAACGAAAGGAATTGTCAGTGGTTTGAACCGTAATATTCCAGTCGATATTAACGGTGATC
AACAGCCAGATTGGCAAACCGAAGTCCTTCAAACCGATGCAGCCATCAACCCAGGTAACAGTGGCGGTGCGCTCATCAAT
CTGCAAGGCGAAGTCATCGGAATCAACTCTATGAAAATCGCAAAAGCCGAAGTTGAAGGAATAGGATTCTCTATCCCAAT
GGACGTTGCTAAACCTGTCATTGAAGATTTAGAGACGAACGGCGAAGTTGAGCGTCCTTACATGGGAGTTTCCCTGCAAG
ACTTGAACCAAATCCCTAACCCTGTGTTACAACGTGAACTAGGGTTGCCAGAAAAAGTGACTGAAGGCGTCCTCGTCCAA
GGCGTCGAAAAAGGCTCCCCTGCTGATGAAGCAGGACTTGAAAAGTACGATGTCATCACCGCCATCGACGGAAATGAAAT
CGAGTCACTCATCAGCTTGCGACAGTATCTCTACAACCAAGCACAAGACGGAGATACAGCCGAGCTTGAAGTTTACCGTG
ACGGCAAACCAACCACCGTCCAAATTACGCTAACCTCTCGATAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(142-226)

Trypsin-like peptidase domain (Trypsin_2)

(4-88)

PDZ domain (PDZ_2)

(126-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

50

98.678

0.493
  htrA Streptococcus pneumoniae Rx1

49.554

98.678

0.489
  htrA Streptococcus pneumoniae D39

49.554

98.678

0.489
  htrA Streptococcus pneumoniae TIGR4

49.554

98.678

0.489
  htrA Streptococcus pneumoniae R6

49.554

98.678

0.489
  htrA Streptococcus gordonii str. Challis substr. CH1

46.352

100

0.476
  htrA Streptococcus mutans UA159

46.087

100

0.467