NTDB

Overview

Name	ruvA	Type	Machinery gene
Locus tag	V5F97_RS09220	Genome accession	NZ_CP145057
Coordinates	1768397..1768981 (+)	Length	194 a.a.
NCBI ID	WP_003689924.1	Uniprot ID	Q5F636
Organism	Neisseria gonorrhoeae strain WHO_alpha_2024
Function	homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1763397..1773981

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V5F97_RS09190 (V5F97_09230)	-	1764327..1765115 (-)	789	WP_003689910.1	class I SAM-dependent methyltransferase	-
V5F97_RS09195 (V5F97_09235)	bioH	1765112..1765861 (-)	750	WP_010360850.1	pimeloyl-ACP methyl ester esterase BioH	-
V5F97_RS09200 (V5F97_09240)	-	1765860..1766585 (+)	726	WP_003689912.1	ComF family protein	-
V5F97_RS09205 (V5F97_09245)	trmL	1766650..1767114 (+)	465	WP_003689916.1	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	-
V5F97_RS09210 (V5F97_09250)	-	1767242..1767928 (+)	687	WP_003689919.1	septal ring lytic transglycosylase RlpA family protein	-
V5F97_RS09215 (V5F97_09255)	-	1767989..1768315 (+)	327	WP_003689921.1	PepSY domain-containing protein	-
V5F97_RS09220 (V5F97_09260)	ruvA	1768397..1768981 (+)	585	WP_003689924.1	Holliday junction branch migration protein RuvA	Machinery gene
V5F97_RS09225 (V5F97_09265)	-	1768981..1769118 (+)	138	WP_003689926.1	hypothetical protein	-
V5F97_RS09230 (V5F97_09270)	-	1769144..1771000 (+)	1857	WP_003689927.1	ABC transporter ATP-binding protein	-
V5F97_RS09235 (V5F97_09275)	rsgA	1771005..1771928 (+)	924	WP_003689928.1	ribosome small subunit-dependent GTPase A	-
V5F97_RS09240 (V5F97_09280)	-	1772041..1772265 (+)	225	WP_003689929.1	exodeoxyribonuclease VII small subunit	-
V5F97_RS09245 (V5F97_09285)	-	1772249..1773145 (+)	897	WP_003691917.1	polyprenyl synthetase family protein	-
V5F97_RS09250 (V5F97_09290)	-	1773262..1773561 (-)	300	WP_010359269.1	DUF2818 family protein	-

Sequence

Protein

Download Length: 194 a.a. Molecular weight: 20729.99 Da Isoelectric Point: 6.4967

                                >NTDB_id=849664 V5F97_RS09220 WP_003689924.1 1768397..1768981(+) (ruvA) [Neisseria gonorrhoeae strain WHO_alpha_2024]

MISRLTGKLVEKNPPQIVIDVNGVGYEADVSMQTFYNLPPVGESVQLFTQLIIREDAHLLFGFATAEERKTFRQLIKVGG

IGAKTALGILSAMTADELARAVAEEDVKRLSSAPGIGKKTAERMVLELRGKLVAHTVTDGLFAASPAADETEDIVSTLLA

LGYNEREAKAAVKGVPKGTDVGEGVRLALKNLLK

Nucleotide

Download Length: 585 bp

                                >NTDB_id=849664 V5F97_RS09220 WP_003689924.1 1768397..1768981(+) (ruvA) [Neisseria gonorrhoeae strain WHO_alpha_2024]

ATGATCAGCAGACTGACCGGCAAACTGGTTGAAAAAAACCCTCCGCAAATCGTCATCGATGTCAACGGTGTCGGTTATGA

AGCCGACGTATCGATGCAGACCTTCTACAACCTGCCGCCCGTGGGTGAAAGCGTACAACTGTTTACCCAGCTTATCATTC

GGGAAGACGCACATCTTTTATTTGGTTTTGCCACTGCGGAAGAACGCAAGACCTTCCGCCAACTGATTAAGGTCGGCGGC

ATCGGCGCGAAAACGGCTTTGGGCATTTTGTCGGCGATGACGGCAGACGAGCTGGCGCGGGCGGTTGCAGAAGAAGATGT

CAAACGCCTCTCCTCCGCTCCGGGAATCGGCAAAAAAACCGCCGAACGTATGGTCTTGGAACTGCGCGGCAAGCTGGTCG

CGCATACGGTAACGGACGGGCTGTTTGCCGCCTCACCCGCCGCCGACGAAACGGAAGACATCGTCAGCACGCTGCTTGCG

CTGGGTTACAACGAACGCGAGGCAAAAGCGGCGGTCAAAGGCGTTCCGAAGGGGACGGACGTGGGCGAAGGCGTGCGCCT

TGCCCTGAAAAACCTGCTGAAATAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(72-129)

RuvA N terminal domain (RuvA_N)

(1-62)

RuvA, C-terminal domain (RuvA_C)

(150-192)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	Q5F636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ruvA	Streptococcus pneumoniae R6	38	100	0.392
ruvA	Streptococcus pneumoniae D39	38	100	0.392
ruvA	Streptococcus pneumoniae TIGR4	37.5	100	0.387
ruvA	Bacillus subtilis subsp. subtilis str. 168	34.951	100	0.371

Detailed information NTG0849664