Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   V5G12_RS00645 Genome accession   NZ_CP145021
Coordinates   137462..137743 (+) Length   93 a.a.
NCBI ID   WP_003696701.1    Uniprot ID   A0A0H4IVZ5
Organism   Neisseria gonorrhoeae strain WHO_V_2024     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 132462..142743
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5G12_RS00610 (V5G12_00615) - 132776..133003 (+) 228 WP_003694773.1 hypothetical protein -
  V5G12_RS00615 (V5G12_00620) - 133078..133350 (+) 273 WP_226888059.1 hypothetical protein -
  V5G12_RS00620 (V5G12_00625) - 133411..134685 (+) 1275 WP_003690587.1 HlyD family secretion protein -
  V5G12_RS00625 (V5G12_00630) - 134870..135217 (+) 348 WP_003687399.1 hypothetical protein -
  V5G12_RS00630 (V5G12_00635) - 135231..135446 (+) 216 WP_003687400.1 hypothetical protein -
  V5G12_RS00635 (V5G12_00640) - 135548..137266 (+) 1719 Protein_124 peptidase domain-containing ABC transporter -
  V5G12_RS00640 (V5G12_00645) - 137267..137383 (-) 117 Protein_125 IS5/IS1182 family transposase -
  V5G12_RS00645 (V5G12_00650) comA 137462..137743 (+) 282 WP_003696701.1 ATP-binding cassette domain-containing protein Regulator
  V5G12_RS00650 (V5G12_00655) - 137764..138990 (-) 1227 WP_003690589.1 YihY family inner membrane protein -
  V5G12_RS00655 (V5G12_00660) - 139089..139294 (+) 206 Protein_128 NAD(P)H-quinone oxidoreductase -
  V5G12_RS00660 (V5G12_00665) queC 139479..140138 (+) 660 WP_003690590.1 7-cyano-7-deazaguanine synthase QueC -
  V5G12_RS00665 (V5G12_00670) - 140166..140681 (+) 516 WP_003687408.1 DUF1543 domain-containing protein -
  V5G12_RS00670 (V5G12_00675) queD 140769..141203 (+) 435 WP_003690591.1 6-carboxytetrahydropterin synthase QueD -
  V5G12_RS00675 (V5G12_00680) - 141474..141842 (+) 369 WP_003690592.1 DUF1304 domain-containing protein -
  V5G12_RS00680 (V5G12_00685) - 141839..142477 (+) 639 WP_012503371.1 7-carboxy-7-deazaguanine synthase QueE -

Sequence

Protein


Download         Length: 93 a.a.        Molecular weight: 10117.78 Da        Isoelectric Point: 6.4598

>NTDB_id=848674 V5G12_RS00645 WP_003696701.1 137462..137743(+) (comA) [Neisseria gonorrhoeae strain WHO_V_2024]
MIREEISAMPMGYETLIGDMGSALSGGQKQRIVLARALYCEPKILFLDEAASHLDIANEKAVNANLNGLSIIKIMAAHRK
ETVESADRKMSLG

Nucleotide


Download         Length: 282 bp        

>NTDB_id=848674 V5G12_RS00645 WP_003696701.1 137462..137743(+) (comA) [Neisseria gonorrhoeae strain WHO_V_2024]
ATGATTCGCGAAGAAATCTCCGCCATGCCTATGGGCTATGAAACCTTGATCGGCGATATGGGCAGCGCACTGTCAGGCGG
ACAAAAACAACGTATCGTATTGGCGCGGGCCTTATATTGCGAACCGAAAATCCTATTTTTAGATGAAGCGGCCAGTCATT
TGGATATTGCCAATGAAAAAGCAGTCAATGCAAACTTGAATGGCTTGTCTATTATAAAAATTATGGCGGCACACAGAAAG
GAAACGGTGGAATCAGCAGATAGGAAAATGTCTTTAGGATAA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(14-51)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H4IVZ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

46.154

97.849

0.452
  comA Streptococcus mitis NCTC 12261

45.055

97.849

0.441
  comA Streptococcus pneumoniae TIGR4

45.055

97.849

0.441
  comA Streptococcus pneumoniae Rx1

45.055

97.849

0.441
  comA Streptococcus pneumoniae R6

45.055

97.849

0.441
  comA Streptococcus pneumoniae D39

45.055

97.849

0.441
  comA/nlmT Streptococcus mutans UA159

47.126

93.548

0.441
  comA Streptococcus gordonii str. Challis substr. CH1

43.956

97.849

0.43