Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   L6410_RS09130 Genome accession   NZ_AP024276
Coordinates   1819068..1819784 (-) Length   238 a.a.
NCBI ID   WP_024391398.1    Uniprot ID   A0A6L8MVD9
Organism   Streptococcus parasuis strain SUT-286     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1814068..1824784
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6410_RS09110 (SUT286_17740) - 1814432..1815658 (-) 1227 WP_237395370.1 cysteine desulfurase -
  L6410_RS09115 (SUT286_17750) sufD 1815663..1816925 (-) 1263 WP_172055597.1 Fe-S cluster assembly protein SufD -
  L6410_RS09120 (SUT286_17760) sufC 1816942..1817715 (-) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  L6410_RS09125 (SUT286_17770) - 1817887..1819071 (-) 1185 WP_024391399.1 glycosyltransferase family 4 protein -
  L6410_RS09130 (SUT286_17780) mecA 1819068..1819784 (-) 717 WP_024391398.1 adaptor protein MecA Regulator
  L6410_RS09135 (SUT286_17790) - 1819989..1820828 (-) 840 WP_160863741.1 undecaprenyl-diphosphate phosphatase -
  L6410_RS09140 (SUT286_17800) - 1821092..1822654 (+) 1563 WP_237395371.1 ABC transporter substrate-binding protein/permease -
  L6410_RS09145 (SUT286_17810) - 1822647..1823390 (+) 744 WP_237395372.1 amino acid ABC transporter ATP-binding protein -
  L6410_RS09150 (SUT286_17820) - 1823604..1823813 (-) 210 WP_024391394.1 hypothetical protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27807.44 Da        Isoelectric Point: 4.1340

>NTDB_id=84492 L6410_RS09130 WP_024391398.1 1819068..1819784(-) (mecA) [Streptococcus parasuis strain SUT-286]
MKVKQISDSTLKITIQLEDLEERGMEIADFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDKVDIFVTKSEM
DQSLNFDEFTDLSELGDVSRMTPDELLKSLERTVRERSAHDSKAVRQLEDAEKEDSDEYQEPYIYYILEFPALIDAVNFV
QTVDYPVEESELYKVEQTYYMTVLINVAERSKQYPEYILSRMLEFTNDTKLTRPFLQEHGILMLGNGAIDELKKVQTA

Nucleotide


Download         Length: 717 bp        

>NTDB_id=84492 L6410_RS09130 WP_024391398.1 1819068..1819784(-) (mecA) [Streptococcus parasuis strain SUT-286]
ATGAAAGTAAAACAAATAAGTGATTCGACTTTAAAAATCACTATCCAATTAGAAGATTTAGAGGAGCGCGGGATGGAAAT
TGCGGATTTTCTTATCCCTCAAGAAAAGACAGAAGAGTTTTTTTATACAGTATTGGATGAATTGGATTTGCCAATGACTT
TCCGAGAAAGTGGAATGCTTAGTTTTAGAGTTACTCCAAAACCGGATAAAGTGGATATTTTTGTCACAAAATCTGAAATG
GATCAAAGTTTAAATTTTGATGAATTTACAGATTTATCGGAATTAGGCGATGTATCAAGAATGACTCCAGATGAATTGCT
GAAAAGTTTGGAACGTACAGTTCGTGAACGAAGCGCGCATGACTCAAAAGCAGTTCGCCAATTAGAAGATGCTGAAAAAG
AAGATAGTGATGAATACCAAGAACCGTATATTTATTATATCTTAGAATTTCCTGCTTTGATTGATGCGGTAAATTTTGTT
CAAACAGTGGATTATCCAGTTGAAGAATCTGAGCTCTACAAGGTGGAACAAACCTATTATATGACAGTATTGATTAATGT
TGCAGAGCGTTCAAAGCAGTATCCGGAATATATTCTATCTCGCATGCTTGAATTTACAAACGATACCAAATTGACACGAC
CATTTCTTCAAGAGCATGGAATCTTGATGTTGGGGAATGGGGCCATAGATGAGTTGAAAAAGGTGCAAACGGCATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6L8MVD9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

49.59

100

0.508
  mecA Streptococcus pneumoniae D39

49.59

100

0.508
  mecA Streptococcus pneumoniae R6

49.59

100

0.508
  mecA Streptococcus pneumoniae TIGR4

49.59

100

0.508
  mecA Streptococcus mutans UA159

47.951

100

0.492
  mecA Streptococcus thermophilus LMD-9

44.048

100

0.466
  mecA Streptococcus thermophilus LMG 18311

43.651

100

0.462

Multiple sequence alignment