Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   QRS93_RS05355 Genome accession   NZ_CP127842
Coordinates   1066043..1066717 (-) Length   224 a.a.
NCBI ID   WP_003060678.1    Uniprot ID   A0AAE9R380
Organism   Streptococcus dysgalactiae subsp. equisimilis strain TPCH-F37     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1061043..1071717
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QRS93_RS05330 (QRS93_05330) - 1061228..1062505 (-) 1278 WP_015017041.1 pyrimidine-nucleoside phosphorylase -
  QRS93_RS05335 (QRS93_05335) - 1062492..1063091 (-) 600 WP_015057597.1 class I SAM-dependent methyltransferase -
  QRS93_RS05340 (QRS93_05340) coaA 1063360..1064280 (+) 921 WP_110408128.1 type I pantothenate kinase -
  QRS93_RS05345 (QRS93_05345) rpsT 1064334..1064582 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  QRS93_RS05350 (QRS93_05350) ciaH 1064740..1066050 (-) 1311 WP_012766987.1 HAMP domain-containing sensor histidine kinase Regulator
  QRS93_RS05355 (QRS93_05355) ciaR 1066043..1066717 (-) 675 WP_003060678.1 response regulator transcription factor Regulator
  QRS93_RS05360 (QRS93_05360) - 1066921..1069458 (-) 2538 WP_042357920.1 M1 family metallopeptidase -
  QRS93_RS05365 (QRS93_05365) phoU 1069659..1070312 (-) 654 WP_015017046.1 phosphate signaling complex protein PhoU -
  QRS93_RS05370 (QRS93_05370) pstB 1070390..1071148 (-) 759 WP_003057749.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25601.58 Da        Isoelectric Point: 4.4684

>NTDB_id=844625 QRS93_RS05355 WP_003060678.1 1066043..1066717(-) (ciaR) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-F37]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFTDKNLAFGNVVVDLGQKEVQVDGRPIELLGKEFDLLVY
LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDFVDKLQTLRSVGYILKSHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=844625 QRS93_RS05355 WP_003060678.1 1066043..1066717(-) (ciaR) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-F37]
ATGATCAAACTATTATTAGTAGAAGATGACTTAAGTTTATCCAATTCCATTTTCGATTTTTTGGATGATTTTGCTGATGT
CACACAAGTTTTTGATGGCGATGAAGGCTTATATGAAGCCGAAAGTGGCATTTACGATTTGATTTTACTTGACCTTATGT
TGCCAGAAAAAAATGGCTTCCAAGTCTTGAAAGAATTGCGAGAAAAAGATATTAAAATTCCTGTGCTGATTATGACAGCC
AAAGAAAGCCTAGATGATAAGGGACATGGCTTTGAATTAGGAGCAGATGATTACCTCACTAAGCCTTTTTACCTGGAGGA
ACTCAAGATGCGAATTCAAGCCCTGTTAAAACGTACGGGGAAATTCACGGATAAAAATCTAGCCTTTGGGAATGTCGTAG
TGGATTTAGGACAAAAAGAAGTTCAAGTGGATGGCCGGCCGATAGAACTATTAGGTAAAGAGTTTGATTTGTTGGTCTAC
CTTTTACAAAATCAGAATGTTATTTTACCTAAAACACAAATTTTTGATCGCTTATGGGGTTTTGATAGCGATACGACCAT
TTCAGTAGTTGAAGTTTACGTTTCTAAAATTAGAAAAAAACTGAAAGGTACAGATTTTGTGGACAAACTGCAGACATTGA
GAAGCGTGGGGTATATTCTAAAAAGCCATGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(5-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae D39

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae R6

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae TIGR4

84.615

98.661

0.835
  ciaR Streptococcus mutans UA159

84.163

98.661

0.83
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.326

100

0.388
  vicR Streptococcus mutans UA159

35.443

100

0.375