Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   QN079_RS04735 Genome accession   NZ_CP127160
Coordinates   978946..980250 (-) Length   434 a.a.
NCBI ID   WP_010747716.1    Uniprot ID   A0A242C4H0
Organism   Enterococcus sp. FZMF     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 973946..985250
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QN079_RS04705 (QN079_04705) - 973948..974982 (+) 1035 WP_289230467.1 hypothetical protein -
  QN079_RS04710 (QN079_04710) - 975043..975387 (-) 345 WP_005225425.1 peptidase -
  QN079_RS04715 (QN079_04715) pepA 975680..976756 (+) 1077 WP_060791847.1 glutamyl aminopeptidase -
  QN079_RS04720 (QN079_04720) - 976890..977210 (+) 321 WP_034857755.1 thioredoxin family protein -
  QN079_RS04725 (QN079_04725) - 977223..977684 (+) 462 WP_005225429.1 universal stress protein -
  QN079_RS04730 (QN079_04730) ytpR 978262..978876 (+) 615 WP_005225431.1 YtpR family tRNA-binding protein -
  QN079_RS04735 (QN079_04735) htrA 978946..980250 (-) 1305 WP_010747716.1 trypsin-like peptidase domain-containing protein Regulator
  QN079_RS04740 (QN079_04740) rlmH 980625..981104 (+) 480 WP_010747717.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  QN079_RS04745 (QN079_04745) truA 981170..981907 (+) 738 WP_005225435.1 tRNA pseudouridine(38-40) synthase TruA -
  QN079_RS04750 (QN079_04750) map 981950..982708 (+) 759 WP_005225436.1 type I methionyl aminopeptidase -
  QN079_RS04755 (QN079_04755) - 983278..984651 (+) 1374 WP_230209433.1 C40 family peptidase -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 44836.30 Da        Isoelectric Point: 4.0084

>NTDB_id=842137 QN079_RS04735 WP_010747716.1 978946..980250(-) (htrA) [Enterococcus sp. FZMF]
MARKYVTPGKKTSPGLLKRLGIGILGGMVGGLLTFGGLYLAMGSSLTSTPETTTNSGVQDSNGQTQVSNVKLDVTSDVTE
AVEKVQDSVVSIINLQQSQSNDWNSLFGQQGGQSEGDSQSDDDSALEASSEGSGVIYKIDGDDAYVVTNNHVVEGQDGLE
VVLADGTKVKAELVGTDAYTDLAVLKISSEHVTTAATFGDSSALKVGEPAIAIGSPLGSDYANSVTQGIVSSLNRQVTSQ
NESGGTISINAIQTDAAINPGNSGGPLINVDGQVIGINSSKIASTSGSASGVSVEGMGFAIPSNDVVEIINQLEADGKVV
RPALGIQTIDLGSITSQQQEQILKVPSSVTSGVVIYSVNNATPAEQAGLQQYDVITKIDDTEVSTTTDLQSALYKHKVGD
TITVTFYRGDEEKTAEVKLSVDTSINEQSTDSSN

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=842137 QN079_RS04735 WP_010747716.1 978946..980250(-) (htrA) [Enterococcus sp. FZMF]
ATGGCAAGAAAATATGTCACACCAGGCAAGAAAACTTCTCCTGGTTTATTAAAACGATTAGGTATTGGGATTTTAGGCGG
TATGGTCGGCGGTTTATTGACCTTCGGCGGTCTGTATCTGGCAATGGGTTCCTCTTTGACTTCAACACCAGAAACCACGA
CCAACAGCGGGGTCCAAGATTCTAACGGACAAACCCAAGTATCCAATGTAAAACTTGATGTGACTAGCGATGTCACTGAG
GCAGTTGAAAAAGTACAAGATTCTGTCGTTTCCATCATTAATCTACAACAAAGTCAAAGCAACGACTGGAACAGCCTCTT
TGGTCAGCAAGGCGGACAAAGTGAAGGCGATAGCCAAAGCGACGACGACAGTGCTTTAGAAGCTTCTTCTGAAGGGAGTG
GAGTCATCTACAAAATCGATGGCGACGATGCCTATGTTGTAACCAACAACCACGTCGTAGAAGGTCAAGACGGTTTGGAA
GTTGTTTTAGCAGACGGTACGAAAGTTAAAGCTGAATTGGTCGGTACTGACGCTTACACAGACTTAGCTGTATTGAAAAT
CTCTTCAGAGCATGTGACGACTGCCGCAACATTTGGTGATTCAAGTGCCTTGAAAGTCGGCGAACCAGCCATCGCGATCG
GTTCACCTCTCGGCTCTGACTACGCAAACTCTGTGACACAAGGGATCGTTTCTTCCTTGAATCGTCAAGTAACAAGCCAA
AACGAATCTGGTGGTACGATCAGCATCAATGCGATCCAAACGGATGCTGCGATCAACCCAGGGAACTCAGGTGGTCCACT
GATCAACGTTGATGGTCAAGTGATTGGGATCAACTCAAGTAAAATCGCCAGCACCTCTGGCTCTGCTTCAGGTGTTAGTG
TGGAAGGGATGGGCTTTGCGATCCCAAGTAACGATGTCGTTGAAATCATCAATCAACTAGAAGCAGACGGCAAAGTGGTT
CGCCCTGCACTAGGGATCCAAACGATCGATTTAGGTTCCATCACATCACAACAACAAGAACAAATCTTGAAAGTTCCTTC
ATCCGTAACTTCTGGCGTTGTGATCTACTCAGTCAACAATGCAACACCAGCAGAACAAGCAGGATTGCAACAATATGACG
TTATCACGAAGATCGATGACACAGAAGTCAGCACAACAACGGATCTGCAATCTGCGTTGTACAAACACAAAGTCGGTGAC
ACGATCACTGTAACCTTCTATCGTGGCGATGAAGAAAAAACGGCAGAAGTAAAACTTTCCGTTGATACGTCGATCAACGA
ACAATCAACAGACAGCAGCAACTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(19-420)

Trypsin-like peptidase domain (Trypsin_2)

(132-277)

PDZ domain (PDZ_2)

(322-419)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A242C4H0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.423

91.475

0.516
  htrA Streptococcus gordonii str. Challis substr. CH1

50.835

96.544

0.491
  htrA Streptococcus mitis NCTC 12261

55.71

82.719

0.461
  htrA Streptococcus pneumoniae TIGR4

57.31

78.802

0.452
  htrA Streptococcus pneumoniae D39

57.31

78.802

0.452
  htrA Streptococcus pneumoniae Rx1

57.31

78.802

0.452
  htrA Streptococcus pneumoniae R6

57.31

78.802

0.452