Detailed information NTG0840869

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: VKP34_RS02070
• Genome accession: NZ_CP142358
• Coordinates: 393493..395646 (-)
• Length: 717 a.a.
• NCBI ID: WP_136112293.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 6702-99
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 388493..400646

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP34_RS02050 (VKP34_02050)	comE/blpR	389684..390433 (+)	750	WP_002992578.1	response regulator transcription factor	Regulator
VKP34_RS02055 (VKP34_02055)	-	390434..391768 (+)	1335	WP_014635339.1	sensor histidine kinase	-
VKP34_RS02060 (VKP34_02060)	-	391916..392041 (-)	126	WP_011017462.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
VKP34_RS02065 (VKP34_02065)	-	392118..393482 (-)	1365	WP_014635340.1	bacteriocin secretion accessory protein	-
VKP34_RS02070 (VKP34_02070)	comA/nlmT	393493..395646 (-)	2154	WP_136112293.1	peptide cleavage/export ABC transporter	Regulator
VKP34_RS02075 (VKP34_02075)	-	396098..396784 (+)	687	Protein_362	transposase	-
VKP34_RS02080 (VKP34_02080)	-	396972..397217 (+)	246	WP_002994504.1	Blp family class II bacteriocin	-
VKP34_RS02085 (VKP34_02085)	-	397232..397414 (+)	183	WP_002987564.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
VKP34_RS02090 (VKP34_02090)	-	397605..398291 (-)	687	Protein_365	transposase	-
VKP34_RS02095 (VKP34_02095)	-	398609..398836 (+)	228	WP_012560514.1	Blp family class II bacteriocin	-
VKP34_RS02100 (VKP34_02100)	-	398849..399049 (+)	201	WP_003060803.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
VKP34_RS02105 (VKP34_02105)	-	399410..399538 (+)	129	WP_002985724.1	hypothetical protein	-
VKP34_RS02110 (VKP34_02110)	-	399588..399869 (+)	282	WP_011054252.1	hypothetical protein	-
VKP34_RS02115 (VKP34_02115)	-	400063..400464 (+)	402	WP_023605036.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80557.48 Da
• Isoelectric Point: 7.0109

>NTDB_id=840869 VKP34_RS02070 WP_136112293.1 393493..395646(-) (comA/nlmT) [Streptococcus pyogenes strain 6702-99]
MISYRKTFVAQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTNKEGTTALGIVKAAKLMGFETRAIQADMTLFDIEDV
PYPFIVHINKEGKFQHYYVVYQNKKNYLIIGDPDPTVKVTKMTKERFTSEWTGVAIFLAPEPSYKPHKDKKNGLINFLPL
IFKQRSLIFYIILASLLVTLINIVGSYYLQGILDDYIPNQLKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANAIIDALASTILSLFLDVSILTIVGTVLLVQNTNLFLLSLVSVPLYIV
IIFIFMHPFEKMNNDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQKIDSEFVDYLDKSFKLSKYSILQSSLKQGAQL
ILNVIVLWFGAKLVMGGKISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVDSEFQEAGTLVNQELL
HGDIQFEELSYKYGFGRDTLSNINLTIKQGDKVSLVGISGSGKTTLAKMIVNFFEPYNGRITINHNDLKMIDKKSLRQHI
NYLPQQAYIFNGSILENLTLGANDCTSHEDILRACEVAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKRVIDNLLAMTDKTIIFVAHRLSISARTNQVIVLDEGKIIETGSHQELMTKQGFYHHLFSG

Nucleotide

• Length: 2154 bp

>NTDB_id=840869 VKP34_RS02070 WP_136112293.1 393493..395646(-) (comA/nlmT) [Streptococcus pyogenes strain 6702-99]
ATGATATCCTATCGAAAAACATTTGTTGCTCAGATTGATGCTAGAGACTGTGGTGTGGCTGCTCTTGCTTCCATCGCTAA
ATATTACGGTTCAGACTACTCTTTAGCTCATTTAAGAGAGTTAGCTAAAACAAATAAAGAGGGAACAACAGCGCTTGGCA
TCGTCAAAGCTGCCAAATTAATGGGGTTTGAAACAAGAGCTATTCAAGCAGACATGACCCTCTTTGATATAGAAGATGTC
CCTTATCCTTTTATTGTTCATATTAATAAAGAAGGTAAATTCCAACACTACTATGTCGTCTATCAAAACAAAAAAAATTA
TCTGATAATCGGCGACCCTGACCCGACAGTAAAAGTCACTAAGATGACAAAGGAGCGATTTACTTCTGAATGGACGGGTG
TCGCTATTTTTCTAGCACCCGAGCCCAGCTACAAGCCTCATAAGGACAAAAAGAACGGTCTAATAAACTTTTTACCTCTT
ATTTTTAAACAGCGATCTCTGATTTTCTATATCATATTAGCTAGCCTACTCGTTACTCTGATTAATATTGTAGGTTCTTA
TTACCTACAAGGTATATTAGATGACTATATTCCAAATCAACTGAAATCAACACTCGGCATTATTTCAATTGGTCTTATCA
TTACCTATATCCTCCAACAGATGATGAGTTTTTCGCGAGATTATCTCCTGACTGTACTGAGTCAGCGATTAAGCATTGAC
GTCATTTTATCTTACATTCGCCATATTTTTGAATTACCCATGTCTTTTTTTGCAACTCGCAGAACAGGAGAAATCATTTC
ACGGTTTACAGATGCTAATGCTATTATTGATGCACTCGCTTCTACTATTTTGTCTCTTTTTCTTGATGTCAGTATTTTAA
CTATCGTAGGGACAGTCCTGTTAGTGCAAAATACCAATCTTTTTCTTCTATCTCTGGTTTCAGTCCCTCTATATATTGTT
ATTATCTTTATATTTATGCACCCATTTGAAAAGATGAATAATGATGTCATGCAGAGTAACTCTATGGTTAGCTCAGCCAT
TATCGAAGATATCAATGGCATTGAAACTATTAAATCACTGACCAGTGAAGAAAATCGTTATCAGAAAATTGATAGTGAAT
TTGTGGACTATCTGGATAAATCTTTCAAGTTAAGTAAGTACTCTATTTTACAAAGCAGTCTCAAACAAGGGGCGCAACTA
ATCCTTAACGTGATAGTCTTATGGTTTGGGGCCAAATTAGTTATGGGAGGAAAAATTTCTGTTGGTCAGTTGATTACGTT
TAATACTCTCTTATCTTATTTTACCAATCCTTTAGAAAATATCATTAATCTTCAAACCAAACTTCAATCAGCCAAGGTAG
CTAATAATCGTCTCAATGAAGTTTACCTAGTCGATTCTGAATTTCAAGAGGCTGGGACATTAGTCAATCAAGAATTATTA
CACGGAGACATTCAATTTGAAGAGTTATCCTATAAATATGGCTTTGGACGCGATACTCTATCAAATATTAATCTCACTAT
TAAGCAAGGGGACAAAGTTAGCCTTGTTGGTATTAGTGGATCTGGTAAAACGACTCTAGCTAAAATGATTGTTAATTTTT
TTGAGCCTTATAACGGCCGAATTACCATTAATCATAATGACTTAAAAATGATTGATAAAAAAAGTCTTCGCCAACATATT
AATTATCTCCCCCAACAAGCCTATATTTTTAATGGTTCTATTTTAGAAAATTTAACCTTAGGTGCTAATGACTGTACTAG
TCATGAAGATATTCTAAGAGCTTGTGAGGTTGCAGAAATTCGACAAGATATTGAACAAATGCCTATGGGCTATCAAACAG
AGCTTTCTGATGGTGCCGGACTCTCAGGAGGCCAAAAGCAACGAATTGCGCTTGCCAGAGCTCTCCTAACCAAGGCGCCT
GTGCTTATTCTAGATGAGGCTACAAGCGGTCTTGACGTACTAACTGAAAAGAGGGTTATTGATAATCTTTTGGCTATGAC
GGATAAAACTATTATTTTCGTAGCTCATCGTCTCAGCATTTCAGCGCGGACCAATCAAGTCATTGTGCTTGATGAGGGCA
AAATTATTGAAACAGGATCTCATCAAGAATTAATGACTAAACAAGGTTTCTATCATCATTTATTTAGTGGTTAA

Domains

Predicted by InterProScan.

• ABC transporter transmembrane region (ABC_membrane) (168-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.867	99.721	0.727
comA	Streptococcus mitis NCTC 12261	67.511	99.163	0.669
comA	Streptococcus mitis SK321	67.089	99.163	0.665
comA	Streptococcus pneumoniae Rx1	67.089	99.163	0.665
comA	Streptococcus pneumoniae D39	67.089	99.163	0.665
comA	Streptococcus pneumoniae R6	67.089	99.163	0.665
comA	Streptococcus pneumoniae TIGR4	66.807	99.163	0.662
comA	Streptococcus gordonii str. Challis substr. CH1	66.294	99.721	0.661