Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   VOI49_RS06940 Genome accession   NZ_CP142018
Coordinates   1380141..1382384 (-) Length   747 a.a.
NCBI ID   WP_226323453.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain lu24     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1375141..1387384
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VOI49_RS06920 - 1375750..1376970 (+) 1221 WP_115252980.1 DUF3114 domain-containing protein -
  VOI49_RS06925 - 1377090..1378151 (-) 1062 Protein_1316 serine hydrolase -
  VOI49_RS06930 sodA 1378318..1378923 (-) 606 WP_003051555.1 superoxide dismutase SodA -
  VOI49_RS06935 holA 1379013..1380059 (-) 1047 WP_226313783.1 DNA polymerase III subunit delta -
  VOI49_RS06940 comEC/celB 1380141..1382384 (-) 2244 WP_226323453.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  VOI49_RS06945 comEA/celA/cilE 1382365..1383027 (-) 663 WP_003051564.1 helix-hairpin-helix domain-containing protein Machinery gene
  VOI49_RS06950 - 1383424..1384164 (-) 741 WP_003051567.1 lysophospholipid acyltransferase family protein -
  VOI49_RS06955 - 1384282..1385058 (+) 777 WP_126426874.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  VOI49_RS06960 - 1385048..1385326 (+) 279 WP_115246202.1 GIY-YIG nuclease family protein -
  VOI49_RS06965 - 1385350..1387350 (-) 2001 WP_226313825.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 747 a.a.        Molecular weight: 85144.74 Da        Isoelectric Point: 9.5561

>NTDB_id=839200 VOI49_RS06940 WP_226323453.1 1380141..1382384(-) (comEC/celB) [Streptococcus dysgalactiae strain lu24]
MNYRWIKWSPLPPIQLAFLVMALYYQIYCPSWLTCLLSSCLGMLLLKQFPQQTLCKVVMILALFAAVFVYRKHQLRQQLE
TQPLQVSQVALVPDSIRINGNQLAVIGRHGNHSYQLFYRFKHQMEARFFQKEYRWIVMHAKIVLDKAETSRNFRGFNYQS
FLAYQGIYRIGKVEQVEQLEVVSPKSVGDYLSSLRRQAIVHCQQSFPKPMSHYLTGLLFGYLDKSFGEMTDYYSQLGIIH
LFALSGMQVGFFLTCFRRGLTLLAIPLEWIKWIELPFACLYAALTGYSISVIRSLLQAQLGHLGIKGLNNLAYAFLLVLL
WNAHALMTVGGVLTFSYAFILTVITFEELSGVKKHFVQVVTVSLGMLPFLLFYLASFNPMSMVLTGLLSYLFDVLILPLL
CLVFCLSPLITLSGCNYLFLFLEKVIQFLGNTLNVSLVFGSPTSWHLLILVISFAILYDHRQIRQRVITCGLLIGLTLLS
VKYPLTNEVTFIDIGQGDSILVRDWTGKNLLIDVGGRLSFSSKEQWRQGHQTSNAQKTLIPYLKSRGIHTIDQLLVTHAD
TDHMGDIEAVAKAIRIKEILTSQGSLSQPSFVRRLRRLKCHVRVLAAGDQLPIMGSVLQVLYPWQLGDGKNNDSLVLYGR
LLNQTFLFTGDLEKEGENEIIERYPQLRVDYLKAGHHGSNTSSSAAFLDHIQPKVAFISAGKNNRYQHPHRETLTRLEDR
GISYYRTDIQGAIRLTGWLNWHIETAR

Nucleotide


Download         Length: 2244 bp        

>NTDB_id=839200 VOI49_RS06940 WP_226323453.1 1380141..1382384(-) (comEC/celB) [Streptococcus dysgalactiae strain lu24]
ATGAACTATCGTTGGATTAAGTGGTCTCCCTTGCCTCCCATTCAACTAGCCTTTTTGGTAATGGCTCTTTATTATCAGAT
CTATTGTCCTAGCTGGTTGACTTGCTTACTTAGCAGCTGTTTAGGAATGTTACTATTGAAGCAGTTTCCTCAACAGACCC
TCTGTAAGGTTGTTATGATTCTGGCCTTATTTGCTGCTGTCTTTGTTTATCGGAAACATCAGTTGAGACAGCAATTGGAA
ACACAACCTTTACAAGTGTCTCAGGTAGCATTGGTTCCGGATAGTATTCGAATTAATGGAAATCAATTAGCTGTTATTGG
GCGTCACGGTAATCATTCTTATCAGTTGTTTTATCGTTTTAAACATCAAATGGAAGCCCGATTTTTCCAAAAAGAGTACC
GTTGGATAGTGATGCATGCCAAAATAGTATTGGACAAGGCTGAGACTTCCCGAAATTTTAGAGGATTTAATTACCAATCT
TTTTTAGCCTATCAGGGAATTTACAGGATAGGAAAAGTGGAACAAGTAGAGCAGCTTGAAGTGGTTTCACCAAAGTCAGT
AGGTGATTATTTATCTTCTTTGAGGCGACAGGCTATTGTCCATTGTCAACAATCCTTTCCAAAGCCCATGTCTCATTATT
TGACAGGACTCCTTTTTGGCTATTTGGATAAGTCCTTTGGTGAGATGACAGATTATTATAGTCAGCTTGGTATCATTCAT
CTTTTTGCCCTATCAGGGATGCAGGTTGGTTTCTTTTTAACCTGTTTTAGAAGAGGTTTGACGCTATTAGCTATTCCTCT
CGAATGGATTAAATGGATAGAACTTCCCTTTGCCTGTCTATATGCTGCGCTGACAGGTTACAGTATTTCTGTTATTCGAA
GCCTTCTGCAGGCCCAATTAGGTCATCTAGGCATAAAAGGTTTAAATAACCTGGCTTACGCTTTCTTACTTGTTCTTTTA
TGGAATGCTCATGCTTTGATGACTGTTGGTGGAGTACTAACATTTAGCTATGCGTTTATCTTAACTGTTATCACTTTTGA
GGAGTTATCGGGAGTTAAAAAGCATTTCGTTCAGGTCGTCACCGTTTCTTTAGGGATGTTACCTTTCTTGCTCTTTTATC
TTGCTAGTTTTAACCCCATGTCAATGGTGTTAACAGGGCTTTTGTCTTATCTCTTCGATGTTTTGATTTTGCCTCTTCTT
TGCTTGGTTTTCTGTTTGTCTCCTTTGATAACTCTCTCAGGATGTAATTATCTCTTTCTTTTCTTAGAAAAAGTCATTCA
ATTTCTTGGGAATACCCTCAATGTCTCCCTTGTTTTTGGAAGTCCGACCAGTTGGCACTTGCTTATCTTGGTGATTAGCT
TCGCTATTCTTTATGACCATCGGCAGATACGACAAAGAGTTATCACTTGCGGCTTGCTCATAGGCCTGACGCTTTTATCT
GTTAAATATCCTTTGACCAATGAAGTGACCTTTATCGACATTGGCCAGGGGGATAGTATTTTAGTGAGGGATTGGACAGG
AAAAAATCTCTTAATAGATGTAGGTGGGCGCCTTTCCTTTTCTTCAAAAGAGCAGTGGCGACAGGGGCACCAGACATCGA
ATGCTCAGAAAACCTTAATTCCTTACTTAAAAAGTAGAGGCATTCACACCATTGACCAATTACTAGTGACTCATGCGGAT
ACTGATCATATGGGGGATATAGAGGCGGTTGCCAAAGCTATTCGGATAAAGGAGATTTTGACTAGCCAAGGTAGTTTAAG
CCAGCCAAGCTTTGTTAGGCGGTTAAGGCGTTTAAAATGTCACGTTAGGGTTTTAGCAGCTGGAGACCAATTGCCTATTA
TGGGAAGTGTCTTACAGGTACTCTATCCTTGGCAGTTAGGGGACGGGAAAAATAATGATTCTCTGGTTCTTTATGGTAGG
CTCCTCAATCAAACTTTTCTATTTACAGGTGATTTGGAAAAAGAGGGGGAAAACGAGATCATAGAACGTTATCCTCAACT
AAGAGTAGATTATTTAAAAGCAGGTCACCATGGATCAAATACCTCTTCTAGTGCAGCTTTTTTAGACCATATTCAGCCTA
AAGTGGCCTTTATTTCTGCTGGAAAAAATAACCGTTATCAGCATCCTCACAGAGAAACCCTAACCCGTTTGGAGGATAGG
GGAATTTCTTATTATCGCACGGATATTCAAGGAGCTATTCGGTTGACAGGGTGGCTAAACTGGCATATTGAGACTGCTCG
TTGA

Domains

Predicted by InterProScan.

Competence protein (Competence)

(217-459)

Metallo-beta-lactamase superfamily (Lactamase_B)

(495-701)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis NCTC 12261

45.638

99.732

0.455
  comEC/celB Streptococcus mitis SK321

45.369

99.732

0.452
  comEC/celB Streptococcus pneumoniae TIGR4

44.712

100

0.447
  comEC/celB Streptococcus pneumoniae Rx1

44.652

100

0.447
  comEC/celB Streptococcus pneumoniae D39

44.652

100

0.447
  comEC/celB Streptococcus pneumoniae R6

44.652

100

0.447
  comEC Lactococcus lactis subsp. cremoris KW2

40.879

100

0.411