Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   LLUL007_RS11350 Genome accession   NZ_CP126569
Coordinates   2175697..2176920 (+) Length   407 a.a.
NCBI ID   WP_396425808.1    Uniprot ID   -
Organism   Lactococcus cremoris strain UL007     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2170697..2181920
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLUL007_RS11325 (LLUL007_11385) - 2171812..2172615 (-) 804 WP_011677190.1 phosphatidate cytidylyltransferase -
  LLUL007_RS11330 (LLUL007_11390) - 2172615..2173349 (-) 735 WP_032951303.1 isoprenyl transferase -
  LLUL007_RS11335 (LLUL007_11395) yajC 2173699..2174031 (-) 333 WP_011677192.1 preprotein translocase subunit YajC -
  LLUL007_RS11340 (LLUL007_11400) - 2174126..2174824 (-) 699 Protein_2207 DNA alkylation repair protein -
  LLUL007_RS11345 (LLUL007_11405) rlmH 2174842..2175321 (-) 480 WP_011677194.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  LLUL007_RS11350 (LLUL007_11410) htrA 2175697..2176920 (+) 1224 WP_396425808.1 S1C family serine protease Regulator
  LLUL007_RS11355 (LLUL007_11415) - 2177042..2178040 (+) 999 WP_396425809.1 glycosyltransferase family 4 protein -
  LLUL007_RS11360 (LLUL007_11420) - 2178178..2179518 (+) 1341 WP_014573350.1 glycosyltransferase family 4 protein -
  LLUL007_RS11365 (LLUL007_11425) - 2179626..2179850 (+) 225 WP_011677198.1 YkuJ family protein -
  LLUL007_RS11370 (LLUL007_11430) - 2179994..2180998 (+) 1005 WP_081172520.1 hypothetical protein -
  LLUL007_RS11375 (LLUL007_11435) - 2181055..2181807 (-) 753 WP_014573352.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 41583.12 Da        Isoelectric Point: 5.7789

>NTDB_id=838754 LLUL007_RS11350 WP_396425808.1 2175697..2176920(+) (htrA) [Lactococcus cremoris strain UL007]
MAKANIGKLLLTGVVGGAIALGGSAIYQSTTNQLGNANRSNTTSTKVSNVSVNVNTDVTSAIKKVSNSVVSVMNYQKQNS
QSDFSSIFGGNSGSSSANDGLKLSSEGSGVIYKKSGGDAYVVTNYHVIAGNSSLDVLLSGGQKVKATVVGYDEYTDLAIL
KISSDHVKDVATFADSSKLTIGEPAIAVGSPLGSQFANTATEGILSATSRQVTLTQENGQTTSINAIQTDAAINPGNSGG
ALINIEGQVIGITQSKITTTEDGSTSVEGLGFAIPSNDVVNIINKLETDGKISRPALGIRMVDLSQLSTNDSSQLKLPSS
VTGGVVVYSVQAGLPAATVGLKAGDVITKVGDTAVTSSTDLQSALYSHNINDTVKVTYYRDGKSATANVKLSKSTSDLET
NSSSSSN

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=838754 LLUL007_RS11350 WP_396425808.1 2175697..2176920(+) (htrA) [Lactococcus cremoris strain UL007]
ATGGCAAAAGCTAATATAGGAAAATTGCTATTAACCGGTGTTGTGGGTGGAGCTATCGCACTCGGAGGAAGCGCAATTTA
TCAAAGCACTACAAACCAACTAGGAAATGCTAACCGCTCAAATACAACTAGCACAAAGGTTAGTAATGTTTCGGTAAATG
TCAATACCGATGTCACCTCTGCAATTAAAAAAGTTTCAAATTCTGTCGTTTCTGTTATGAATTATCAAAAACAGAATTCA
CAAAGTGATTTTAGTTCAATTTTTGGTGGAAATAGCGGCTCAAGTTCAGCTAATGACGGCTTGAAACTTTCCAGTGAGGG
TTCTGGTGTTATTTATAAAAAATCTGGTGGAGATGCTTACGTGGTCACTAACTATCACGTTATTGCTGGAAATAGTTCCC
TCGATGTTTTACTTTCTGGTGGGCAAAAAGTTAAAGCCACAGTTGTTGGTTATGATGAATACACTGACCTTGCCATTCTT
AAAATCAGCTCTGACCATGTTAAAGACGTGGCAACTTTCGCTGATTCAAGCAAGTTAACTATTGGTGAACCAGCTATTGC
AGTCGGCTCACCTTTAGGTAGCCAGTTTGCTAATACTGCAACCGAAGGAATTCTGTCTGCAACAAGTCGTCAAGTCACTT
TGACTCAAGAAAATGGTCAAACAACAAGTATCAATGCGATTCAAACGGATGCTGCCATTAACCCGGGTAACTCAGGTGGA
GCCTTGATTAATATTGAAGGTCAAGTGATTGGTATTACTCAAAGTAAAATCACAACGACCGAAGATGGTTCTACCTCTGT
GGAAGGTTTAGGTTTTGCTATCCCATCTAATGATGTGGTAAACATCATTAATAAACTTGAAACTGATGGTAAGATTTCAC
GTCCCGCCTTAGGTATTCGTATGGTTGACCTATCTCAATTATCAACAAATGATAGTTCTCAACTGAAATTACCTAGCAGC
GTAACTGGTGGAGTGGTTGTCTACTCTGTTCAAGCGGGTCTTCCTGCTGCCACAGTTGGTCTGAAAGCTGGCGATGTGAT
AACGAAGGTGGGAGATACCGCCGTTACTTCATCAACAGACTTACAAAGTGCTCTTTACTCACACAATATTAATGATACTG
TGAAAGTCACCTACTACCGTGATGGTAAATCAGCCACAGCAAATGTTAAACTCTCTAAATCAACAAGCGATTTAGAAACA
AATAGTTCATCTTCTTCTAATTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(295-391)

Trypsin-like peptidase domain (Trypsin_2)

(107-252)

Peptidase family M50 (Peptidase_M50)

(250-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

54.615

95.823

0.523
  htrA Streptococcus mitis NCTC 12261

55.352

94.103

0.521
  htrA Streptococcus pneumoniae Rx1

57.849

84.521

0.489
  htrA Streptococcus pneumoniae D39

57.849

84.521

0.489
  htrA Streptococcus pneumoniae R6

57.849

84.521

0.489
  htrA Streptococcus pneumoniae TIGR4

57.849

84.521

0.489
  htrA Streptococcus mutans UA159

53.117

90.663

0.482