Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   VJ737_RS18030 Genome accession   NZ_CP141909
Coordinates   3999395..4000519 (+) Length   374 a.a.
NCBI ID   WP_184594841.1    Uniprot ID   -
Organism   Streptomyces sp. CGMCC 4.1772     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3994395..4005519
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VJ737_RS18015 (VJ737_18015) - 3994981..3995781 (+) 801 WP_184594847.1 hypothetical protein -
  VJ737_RS18020 (VJ737_18020) - 3996003..3997709 (-) 1707 WP_184594845.1 hypothetical protein -
  VJ737_RS18025 (VJ737_18025) radA 3997905..3999314 (+) 1410 WP_184594843.1 DNA repair protein RadA Machinery gene
  VJ737_RS18030 (VJ737_18030) disA 3999395..4000519 (+) 1125 WP_184594841.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  VJ737_RS18035 (VJ737_18035) - 4000613..4001512 (-) 900 WP_184594839.1 hypothetical protein -
  VJ737_RS18040 (VJ737_18040) - 4001688..4002329 (+) 642 WP_184594837.1 phosphatase PAP2 family protein -
  VJ737_RS18045 (VJ737_18045) - 4002342..4002998 (-) 657 WP_184594835.1 response regulator transcription factor -
  VJ737_RS18050 (VJ737_18050) - 4002995..4004566 (-) 1572 WP_184594833.1 histidine kinase -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 39972.72 Da        Isoelectric Point: 4.9201

>NTDB_id=838693 VJ737_RS18030 WP_184594841.1 3999395..4000519(+) (disA) [Streptomyces sp. CGMCC 4.1772]
MAANDRAAAPGKSGGSAGTDGLMRASLSAVAPGTALRDGLERVLRGNTGGLIVLGSDKTVEALCSGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLVPDPAIPTEETGTRHRTADRVSRQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDALTHAELLELPIVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=838693 VJ737_RS18030 WP_184594841.1 3999395..4000519(+) (disA) [Streptomyces sp. CGMCC 4.1772]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAATCCGGTGGGAGTGCCGGTACCGATGGCCTGATGCGCGCTTCACT
GAGCGCCGTGGCACCCGGAACCGCCCTGCGTGACGGCCTGGAGCGCGTGCTCCGGGGCAACACCGGCGGTCTCATCGTGC
TGGGCTCCGACAAGACGGTCGAGGCGCTGTGCAGCGGCGGTTTCGTGCTGGACGTCGAGTTCACCGCGACCCGCCTGCGC
GAGCTCTGCAAGCTGGACGGCGGCATCGTGCTGTCCTCGGACCTGTCGAAGATCCTGCGCGCGGGCGTGCAGCTGGTCCC
GGACCCGGCGATCCCCACGGAGGAGACCGGCACCCGGCACCGCACCGCGGACCGCGTCAGCAGGCAGGTCGGCTTCCCGG
TGGTCTCGGTCTCCCAGTCGATGCGGCTGATCGCCCTGTACGTCGACGGCCAGCGCCGCGTCCTGGAGGACTCGGCGGCG
ATCCTGTCCCGCGCCAACCAGGCCCTCGCCACCCTGGAGCGCTACAAGCTCCGCCTCGACGAGGTCGCGGGCACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTGACCGTCCGGGACGTCTCGGCGGTCGCCCAGCGCCTGGAGATGGTGCGCCGCATCG
CCACGGAGATCGCCGAGTACGTGGTGGAGCTGGGCACGGACGGGCGCCTGCTGGCCCTCCAGCTCGACGAGCTGATCGCC
GGCGTGGAGCCCGAGCGTGAGCTGGTCGTCCGGGACTACGTCCCCGAGCCCACGGCCAAGCGGTCCCGCACGGTCGACGA
GGCCCTGGCCGAGCTCGACGCCCTCACCCACGCCGAGCTGCTCGAACTGCCCATCGTGGCGCGGGCGTTGGGTTACACGG
GCTCGCCCGAGACGCTGGACTCGGCGGTGTCCCCGCGCGGCTTCCGCCTCCTCGCCAAGGTGCCCCGGCTCCCCGGCGCG
ATCATCGACCGTCTGGTGGAGCACTTCGGCGGCCTGCAGAAACTGCTCGCCGCGAGCGTCGACGACCTCCAGACGGTGGA
CGGCGTGGGCGAGGCCCGGGCGCGCAGCGTGCGGGAAGGCCTGTCGCGGCTGGCGGAGTCGTCGATCCTGGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)

Helix-hairpin-helix motif (HHH_2)

(324-359)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.429

96.524

0.438