Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   VF946_RS00745 Genome accession   NZ_CP141824
Coordinates   117786..118193 (+) Length   135 a.a.
NCBI ID   WP_011921721.1    Uniprot ID   A0A0H3MT39
Organism   Streptococcus suis strain HB18     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 112786..123193
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VF946_RS00720 - 114194..114559 (+) 366 WP_002936568.1 DUF1033 family protein -
  VF946_RS00725 - 114594..115537 (-) 944 Protein_109 S66 peptidase family protein -
  VF946_RS00730 comGA 115623..116573 (+) 951 WP_011921718.1 competence type IV pilus ATPase ComGA Machinery gene
  VF946_RS00735 comGB 116485..117522 (+) 1038 WP_256770774.1 competence type IV pilus assembly protein ComGB Machinery gene
  VF946_RS00740 comGC 117524..117805 (+) 282 WP_011921720.1 competence type IV pilus major pilin ComGC Machinery gene
  VF946_RS00745 comGD 117786..118193 (+) 408 WP_011921721.1 competence type IV pilus minor pilin ComGD Machinery gene
  VF946_RS00750 comGE 118165..118458 (+) 294 WP_011921722.1 competence type IV pilus minor pilin ComGE Machinery gene
  VF946_RS00755 comGF/cglF 118445..118879 (+) 435 WP_011922561.1 competence type IV pilus minor pilin ComGF Machinery gene
  VF946_RS00760 comGG 118857..119267 (+) 411 WP_011921724.1 competence type IV pilus minor pilin ComGG Machinery gene
  VF946_RS00765 comGH 119324..120277 (+) 954 WP_024406069.1 class I SAM-dependent methyltransferase Machinery gene
  VF946_RS00770 - 120327..121514 (+) 1188 WP_012775473.1 acetate kinase -
  VF946_RS00775 - 121827..122378 (+) 552 WP_012775474.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 135 a.a.        Molecular weight: 15367.59 Da        Isoelectric Point: 8.3926

>NTDB_id=838150 VF946_RS00745 WP_011921721.1 117786..118193(+) (comGD) [Streptococcus suis strain HB18]
MLRRKNKAFTLFESLLTLLVVSFLAVSLSGTVQTVFRSVQEEIFLWEFEAIYKDSQKLAASSHKKVNLAIGGQEVTNGYQ
AVEVPRNVEVLEEKTIQFEEDGGNSSLTKIRFHLSQKIVTYQLYIGSGRYKKTEE

Nucleotide


Download         Length: 408 bp        

>NTDB_id=838150 VF946_RS00745 WP_011921721.1 117786..118193(+) (comGD) [Streptococcus suis strain HB18]
ATGCTACGGCGAAAAAATAAGGCTTTTACCCTGTTTGAAAGCCTGCTGACCTTGTTGGTTGTCAGTTTTTTAGCTGTTTC
CTTATCAGGAACAGTACAAACGGTCTTTCGGTCTGTTCAGGAAGAAATTTTTCTCTGGGAATTTGAGGCCATCTATAAAG
ACAGTCAGAAATTAGCAGCCAGTTCCCACAAAAAAGTGAACCTTGCTATCGGTGGACAGGAGGTTACAAATGGTTATCAG
GCTGTAGAGGTGCCCAGAAATGTAGAGGTCTTAGAGGAGAAAACTATTCAGTTTGAAGAAGATGGTGGAAATTCTTCTCT
GACCAAGATTCGTTTTCACCTTAGTCAAAAAATAGTCACGTATCAATTATATATAGGGAGTGGTCGCTATAAGAAAACAG
AAGAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MT39

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus gordonii str. Challis substr. CH1

48.031

94.074

0.452
  comGD Streptococcus mutans UA140

46.512

95.556

0.444
  comGD Streptococcus mutans UA159

46.512

95.556

0.444
  comGD/cglD Streptococcus pneumoniae TIGR4

44.961

95.556

0.43
  comGD/cglD Streptococcus pneumoniae R6

44.961

95.556

0.43
  comGD/cglD Streptococcus pneumoniae Rx1

44.961

95.556

0.43
  comGD/cglD Streptococcus pneumoniae D39

44.961

95.556

0.43
  comGD/cglD Streptococcus mitis NCTC 12261

44.186

95.556

0.422
  comGD/cglD Streptococcus mitis SK321

43.411

95.556

0.415
  comGD Lactococcus lactis subsp. cremoris KW2

39.062

94.815

0.37