Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE1/comEA   Type   Machinery gene
Locus tag   Hhaem_RS01220 Genome accession   NZ_AP024093
Coordinates   248198..248545 (-) Length   115 a.a.
NCBI ID   WP_223893798.1    Uniprot ID   -
Organism   Haemophilus haemolyticus strain 2019-19     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 243198..253545
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Hhaem_RS01195 (Hhaem_02390) thiQ 244014..244661 (-) 648 WP_223893794.1 thiamine ABC transporter ATP-binding protein -
  Hhaem_RS01200 (Hhaem_02400) thiP 244645..246261 (-) 1617 WP_223893795.1 thiamine/thiamine pyrophosphate ABC transporter permease -
  Hhaem_RS01205 (Hhaem_02410) thiB 246266..247264 (-) 999 WP_223893796.1 thiamine ABC transporter substrate binding subunit -
  Hhaem_RS01210 (Hhaem_02420) - 247442..247684 (-) 243 WP_223894350.1 hypothetical protein -
  Hhaem_RS01215 (Hhaem_02430) - 247792..248169 (+) 378 WP_223893797.1 DUF305 domain-containing protein -
  Hhaem_RS01220 (Hhaem_02440) comE1/comEA 248198..248545 (-) 348 WP_223893798.1 helix-hairpin-helix domain-containing protein Machinery gene
  Hhaem_RS01225 (Hhaem_02450) ispH 248716..249660 (-) 945 WP_223893799.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase -
  Hhaem_RS01230 (Hhaem_02460) lspA 249657..250172 (-) 516 WP_065245635.1 signal peptidase II -
  Hhaem_RS01235 (Hhaem_02470) - 250242..251798 (-) 1557 WP_223893800.1 phosphoethanolamine transferase -

Sequence

Protein


Download         Length: 115 a.a.        Molecular weight: 12248.06 Da        Isoelectric Point: 8.0102

>NTDB_id=83420 Hhaem_RS01220 WP_223893798.1 248198..248545(-) (comE1/comEA) [Haemophilus haemolyticus strain 2019-19]
MKLMKTLFTSVVLCGALGASSAFAEEKAAEQVVQPVVATQAEAQVAPATVSDKLNINTATVSEIQKALTGIGAKKAEAIV
QYREKHGNFTSAEQLLEVQGIGKATLERNRDRITF

Nucleotide


Download         Length: 348 bp        

>NTDB_id=83420 Hhaem_RS01220 WP_223893798.1 248198..248545(-) (comE1/comEA) [Haemophilus haemolyticus strain 2019-19]
ATGAAATTAATGAAAACATTATTTACTTCGGTGGTATTGTGCGGGGCTCTAGGTGCGTCTTCGGCTTTTGCTGAGGAAAA
AGCTGCAGAGCAGGTCGTTCAACCTGTTGTGGCAACTCAAGCTGAAGCTCAAGTTGCACCAGCTACTGTGAGTGATAAAT
TGAATATCAATACGGCAACTGTTAGTGAAATTCAAAAAGCCTTAACAGGAATCGGTGCAAAAAAAGCAGAAGCGATAGTG
CAATATCGTGAAAAACACGGTAATTTCACGAGTGCTGAACAACTATTAGAAGTGCAAGGGATTGGTAAAGCAACACTTGA
AAGAAACCGTGATCGAATCACTTTTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(52-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE1/comEA Haemophilus influenzae Rd KW20

85.714

97.391

0.835
  comEA/comE1 Glaesserella parasuis strain SC1401

56.14

99.13

0.557
  comEA Vibrio cholerae C6706

44.037

94.783

0.417
  comEA Vibrio cholerae strain A1552

44.037

94.783

0.417
  comEA Vibrio campbellii strain DS40M4

38.182

95.652

0.365

Multiple sequence alignment