Detailed information NTG0833446

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QM342_RS09265
• Genome accession: NZ_CP125895
• Coordinates: 1908915..1909958 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain CHAL5
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1903915..1914958

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QM342_RS09235 (QM342_09235)	-	1904333..1905589 (-)	1257	WP_001789555.1	aminopeptidase	-
QM342_RS09240 (QM342_09240)	-	1905592..1905792 (-)	201	WP_000180460.1	DUF1128 family protein	-
QM342_RS09245 (QM342_09245)	-	1905939..1906403 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QM342_RS09250 (QM342_09250)	-	1906410..1906685 (+)	276	WP_000428171.1	hypothetical protein	-
QM342_RS09255 (QM342_09255)	-	1906963..1908180 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
QM342_RS09260 (QM342_09260)	vraR	1908296..1908925 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QM342_RS09265 (QM342_09265)	vraS	1908915..1909958 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QM342_RS09270 (QM342_09270)	liaF	1909955..1910656 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QM342_RS09275 (QM342_09275)	-	1910671..1911057 (-)	387	WP_001110179.1	hypothetical protein	-
QM342_RS09280 (QM342_09280)	map	1911274..1912032 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QM342_RS09285 (QM342_09285)	-	1912563..1913549 (+)	987	WP_000999716.1	aromatic acid exporter family protein	-
QM342_RS09290 (QM342_09290)	-	1914039..1914452 (-)	414	WP_001670387.1	hypothetical protein	-
QM342_RS09295 (QM342_09295)	-	1914481..1914591 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=833446 QM342_RS09265 WP_001017131.1 1908915..1909958(-) (vraS) [Staphylococcus aureus strain CHAL5]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=833446 QM342_RS09265 WP_001017131.1 1908915..1909958(-) (vraS) [Staphylococcus aureus strain CHAL5]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAGTTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1