Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   QL280_RS10255 Genome accession   NZ_CP125291
Coordinates   2003436..2004098 (-) Length   220 a.a.
NCBI ID   WP_000649974.1    Uniprot ID   A0A0F7YBW3
Organism   Streptococcus pneumoniae strain 105_Kz     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1998436..2009098
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QL280_RS10230 (QL280_10230) - 1998586..1998852 (-) 267 WP_001278167.1 Veg family protein -
  QL280_RS10235 (QL280_10235) dnaB 1998854..2000206 (-) 1353 WP_000852486.1 replicative DNA helicase -
  QL280_RS10240 (QL280_10240) rplI 2000250..2000702 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  QL280_RS10245 (QL280_10245) - 2000699..2002672 (-) 1974 WP_000715129.1 DHH family phosphoesterase -
  QL280_RS10250 (QL280_10250) raiA 2002808..2003356 (-) 549 WP_000599107.1 ribosome-associated translation inhibitor RaiA -
  QL280_RS10255 (QL280_10255) comFC/cflB 2003436..2004098 (-) 663 WP_000649974.1 ComF family protein Machinery gene
  QL280_RS10260 (QL280_10260) comFA/cflA 2004095..2005393 (-) 1299 WP_282959416.1 DEAD/DEAH box helicase Machinery gene
  QL280_RS10265 (QL280_10265) - 2005449..2006084 (+) 636 WP_000395730.1 YigZ family protein -
  QL280_RS10270 (QL280_10270) cysK 2006369..2007289 (+) 921 WP_000029866.1 cysteine synthase A -
  QL280_RS10275 (QL280_10275) - 2007528..2007893 (-) 366 Protein_1991 IS66 family transposase -
  QL280_RS10280 (QL280_10280) - 2007875..2008183 (+) 309 Protein_1992 transposase -
  QL280_RS10285 (QL280_10285) tnpB 2008374..2008661 (-) 288 WP_000586646.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25169.03 Da        Isoelectric Point: 7.7116

>NTDB_id=830864 QL280_RS10255 WP_000649974.1 2003436..2004098(-) (comFC/cflB) [Streptococcus pneumoniae strain 105_Kz]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=830864 QL280_RS10255 WP_000649974.1 2003436..2004098(-) (comFC/cflB) [Streptococcus pneumoniae strain 105_Kz]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGGAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGTTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBW3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae Rx1

100

100

1
  comFC/cflB Streptococcus pneumoniae D39

100

100

1
  comFC/cflB Streptococcus pneumoniae R6

100

100

1
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.364

100

0.914
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909