Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   QLH56_RS07680 Genome accession   NZ_CP125107
Coordinates   1601851..1603755 (+) Length   634 a.a.
NCBI ID   WP_016356119.1    Uniprot ID   -
Organism   Streptococcus iniae strain DFSM220524     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1596851..1608755
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QLH56_RS07665 (QLH56_07665) fmt 1598829..1599764 (+) 936 WP_003101762.1 methionyl-tRNA formyltransferase -
  QLH56_RS07670 (QLH56_07670) rsmB 1599754..1601076 (+) 1323 WP_003101760.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  QLH56_RS07675 (QLH56_07675) - 1601114..1601854 (+) 741 WP_003101757.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  QLH56_RS07680 (QLH56_07680) pknB 1601851..1603755 (+) 1905 WP_016356119.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  QLH56_RS07685 (QLH56_07685) liaF 1603872..1604567 (+) 696 WP_003101751.1 cell wall-active antibiotics response protein LiaF -
  QLH56_RS07690 (QLH56_07690) - 1604564..1605568 (+) 1005 WP_003101748.1 sensor histidine kinase -
  QLH56_RS07695 (QLH56_07695) - 1605561..1606205 (+) 645 WP_003101747.1 response regulator transcription factor -
  QLH56_RS07700 (QLH56_07700) - 1606238..1607638 (+) 1401 WP_003101746.1 Cof-type HAD-IIB family hydrolase -
  QLH56_RS07705 (QLH56_07705) - 1607638..1607994 (+) 357 WP_003101745.1 S1 RNA-binding domain-containing protein -
  QLH56_RS07710 (QLH56_07710) tnpA 1608130..1608594 (-) 465 Protein_1459 IS200/IS605 family transposase -

Sequence

Protein


Download         Length: 634 a.a.        Molecular weight: 69128.79 Da        Isoelectric Point: 8.9521

>NTDB_id=829975 QLH56_RS07680 WP_016356119.1 1601851..1603755(+) (pknB) [Streptococcus iniae strain DFSM220524]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEEVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYIQGADLKKFIQDNAPLSNTQVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKTLPSIIDENPQVP
QALENVVIKATAKKLSDRYNSTFEMSRDLMTALSYNRSRERKLVFLDVESTKPLPKVTPTPAPKPTVAPVSPSNTTKQKQ
EAIADVPVKKKKSGRFFGTLLKIIFALFVIGVAFFAFLVLTKPSTVKVPNVNGSSLAVAESELKSLGFKIGKVKEIESAT
VAEGNVVKTDPEAGTSKREGSKVDIYVSIGNQSFVMEDYKNQLYEDAVENLVNTYNVPRSKIKIERVVTSDYRKDMVIAQ
SPSPGEKFNPKGKSKIVLSVASNDTVLMPTIVNYTYQDALAALKALGIDSKRVKAYYPDVNSATGFSKMPNPKSTMIISA
QDPYAGVEISLSATSEISIYLYAEEPTANSSDTTTSSNSRSTASSSESHATSSSSSNPNAGTETNTDANVSPQN

Nucleotide


Download         Length: 1905 bp        

>NTDB_id=829975 QLH56_RS07680 WP_016356119.1 1601851..1603755(+) (pknB) [Streptococcus iniae strain DFSM220524]
ATGATACAGATTGGCAAATTATTTGCTGGTCGTTATCGCATCTTAAAATCAATTGGCCGCGGTGGTATGGCGGATGTTTA
CTTAGCCAATGACTTAATCTTAGATAATGAAGAAGTTGCAATTAAAGTTTTGCGAACCAATTATCAAACAGATCAAGTTG
CAGTAGCGCGTTTCCAAAGAGAAGCGCGAGCGATGGCAGAATTAAATCATCCCAACATTGTCGCTATTCGAGATATAGGT
GAAGAAGACGGACAGCAGTTCTTAGTAATGGAATATATCCAGGGCGCTGACCTTAAGAAATTTATTCAAGATAACGCTCC
TTTGTCTAACACCCAAGTTGTTAGAATCATGGAAGAAGTTTTATCTGCTATGACATTAGCCCACCAAAAAGGGATTGTTC
ATAGAGACTTGAAACCTCAAAATATTCTATTAACAAAGTCAGGTGTTGTCAAAGTTACAGACTTTGGTATTGCTGTAGCT
TTTGCTGAAACTAGTTTAACGCAGACAAATTCTATGTTAGGAAGTGTGCATTATTTATCACCAGAACAAGCCCGTGGTTC
AAAAGCCACCATTCAAAGTGATATTTATGCCATGGGAATTATGCTCTTTGAAATGTTAACAGGTCATATCCCATATGATG
GTGATAGTGCTGTTACAATTGCATTGCAGCATTTCCAAAAAACCCTTCCTTCAATTATTGACGAGAACCCGCAAGTTCCA
CAGGCTTTAGAAAATGTTGTTATTAAGGCAACTGCTAAAAAGTTAAGTGATCGTTACAATTCGACATTTGAAATGAGTCG
CGACCTAATGACTGCACTAAGTTATAATCGAAGCCGTGAACGCAAGTTAGTCTTTTTGGATGTTGAAAGCACAAAACCCT
TACCAAAAGTAACCCCGACCCCAGCACCAAAACCAACGGTAGCTCCGGTAAGTCCAAGTAATACCACTAAACAAAAACAA
GAAGCCATTGCTGATGTGCCTGTTAAGAAAAAAAAGAGTGGGCGTTTCTTTGGAACTTTATTAAAGATTATTTTTGCACT
ATTTGTTATCGGTGTTGCGTTTTTTGCCTTTCTTGTCTTGACCAAGCCATCTACCGTAAAAGTTCCAAATGTTAATGGAA
GTAGTCTAGCGGTTGCTGAATCAGAGTTAAAATCTTTAGGGTTTAAGATTGGAAAAGTAAAAGAAATTGAGAGTGCAACC
GTTGCAGAAGGTAATGTTGTTAAAACAGATCCAGAAGCTGGAACTTCAAAACGCGAAGGCTCTAAGGTTGATATTTATGT
TTCAATAGGTAATCAGAGTTTTGTGATGGAAGATTATAAAAATCAACTTTACGAAGATGCCGTTGAAAACCTTGTTAACA
CCTACAATGTTCCAAGGTCGAAAATTAAAATTGAAAGAGTGGTAACATCCGACTATCGTAAGGATATGGTTATTGCCCAG
TCACCTAGTCCAGGTGAGAAATTTAATCCCAAAGGAAAATCGAAGATTGTCCTCAGTGTGGCTAGTAATGACACAGTTTT
AATGCCAACTATTGTTAACTATACTTATCAGGATGCCCTTGCAGCACTAAAAGCTTTAGGAATTGACAGTAAGCGTGTCA
AAGCTTATTATCCTGATGTTAACTCTGCTACTGGCTTTAGCAAGATGCCTAATCCAAAATCAACAATGATTATCAGCGCA
CAAGATCCATATGCAGGTGTAGAGATTTCCTTATCTGCTACTAGCGAGATTAGCATTTACCTTTATGCTGAAGAACCAAC
AGCCAATAGTTCTGATACAACAACATCATCAAACAGTCGAAGTACAGCATCAAGTAGTGAGAGTCATGCCACAAGCAGCT
CATCCTCTAACCCTAACGCAGGTACCGAAACAAACACCGATGCCAATGTATCACCTCAAAACTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-248)

PASTA domain (PASTA)

(366-428)

PASTA domain (PASTA)

(435-501)

PASTA domain (PASTA)

(506-582)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

63.714

92.587

0.59
  stkP/pknB Streptococcus salivarius strain HSISS4

63.589

90.536

0.576
  stkP Streptococcus pneumoniae TIGR4

56.783

81.388

0.462
  stkP Streptococcus pneumoniae D39

56.395

81.388

0.459
  stkP Streptococcus pneumoniae R6

56.395

81.388

0.459
  stkP Streptococcus pneumoniae Rx1

56.202

81.388

0.457