NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	QLH56_RS00430	Genome accession	NZ_CP125107
Coordinates	83208..84053 (-)	Length	281 a.a.
NCBI ID	WP_003099573.1	Uniprot ID	A0A1J0MYY1
Organism	Streptococcus iniae strain DFSM220524
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 78208..89053

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QLH56_RS00415 (QLH56_00415)	-	78774..79832 (-)	1059	WP_003099589.1	PTS sugar transporter subunit IIC	-
QLH56_RS00420 (QLH56_00420)	-	79998..80882 (+)	885	WP_003099578.1	LysR family transcriptional regulator	-
QLH56_RS00425 (QLH56_00425)	topA	80976..83111 (-)	2136	WP_003099575.1	type I DNA topoisomerase	-
QLH56_RS00430 (QLH56_00430)	dprA	83208..84053 (-)	846	WP_003099573.1	DNA-processing protein DprA	Machinery gene
QLH56_RS00435 (QLH56_00435)	-	84119..84667 (-)	549	WP_003099570.1	sugar O-acetyltransferase	-
QLH56_RS00440 (QLH56_00440)	-	84680..85465 (-)	786	WP_003099568.1	ribonuclease HII	-
QLH56_RS00445 (QLH56_00445)	ylqF	85449..86303 (-)	855	WP_003099566.1	ribosome biogenesis GTPase YlqF	-
QLH56_RS00450 (QLH56_00450)	-	86773..87612 (-)	840	WP_003099563.1	alpha/beta hydrolase	-
QLH56_RS00455 (QLH56_00455)	-	87609..88931 (-)	1323	WP_225111305.1	PTS sugar transporter subunit IIC	-

Sequence

Protein

Download Length: 281 a.a. Molecular weight: 31550.74 Da Isoelectric Point: 9.9826

                                >NTDB_id=829937 QLH56_RS00430 WP_003099573.1 83208..84053(-) (dprA) [Streptococcus iniae strain DFSM220524]

MNNFELYKLKKAGLKNHHILNIIHYSQQTKKSLSLRNMAVVSGTSKPCLFLENYKLLNIKELRVEFKKYPSFSILDKTYP

LALKEIDNPPVLLFYQGNLELLNRHKLAVVGSRKSSAVGNKSVESLIKQLNNQFVIVSGLARGIDTVAHFSSIKQGGETI

AVIGSGLDIYYPKENRRLQEFIAEKHLLLSEYCPKEAPLAHHFPERNRIIAGLSMGVLVAEAKWRSGSLITCRFALDYGR

DIFVVPGAILDKQSQGGNHLIQEGAKLVTKGLDIISEYQFL

Nucleotide

Download Length: 846 bp

                                >NTDB_id=829937 QLH56_RS00430 WP_003099573.1 83208..84053(-) (dprA) [Streptococcus iniae strain DFSM220524]

ATGAATAACTTTGAACTGTATAAATTAAAGAAAGCTGGCCTAAAAAATCATCATATTCTAAATATCATTCATTATAGCCA

GCAAACTAAGAAATCTCTATCACTTAGAAATATGGCTGTTGTTTCAGGAACAAGTAAACCATGTCTGTTTTTAGAAAATT

ACAAGCTGTTAAATATAAAAGAGTTACGAGTAGAATTTAAGAAGTATCCCAGCTTTTCAATTTTAGACAAGACCTATCCC

CTTGCTTTAAAAGAAATTGATAATCCGCCAGTATTATTATTTTATCAAGGAAATTTAGAGCTTTTAAATCGGCATAAATT

AGCAGTGGTAGGGTCAAGGAAATCCTCAGCAGTTGGAAACAAATCTGTTGAATCTCTCATCAAGCAACTTAATAATCAGT

TTGTTATTGTTAGTGGGTTGGCTAGAGGAATTGATACTGTAGCTCATTTTTCGAGCATCAAACAAGGTGGAGAGACTATT

GCTGTTATTGGATCAGGGTTAGACATTTATTATCCTAAGGAAAATAGAAGATTACAGGAGTTTATTGCTGAAAAGCATTT

ATTATTAAGTGAATATTGCCCTAAGGAAGCACCTTTAGCACATCATTTTCCAGAACGAAATCGCATAATTGCAGGCTTAT

CTATGGGAGTTTTAGTGGCAGAAGCCAAATGGCGTTCTGGTAGTCTAATCACTTGTCGCTTTGCACTTGATTACGGTAGG

GATATTTTTGTTGTTCCAGGCGCCATCCTTGACAAACAGTCGCAGGGAGGGAATCACCTCATTCAAGAGGGAGCGAAGCT

TGTTACAAAAGGACTTGACATCATTTCTGAATACCAATTTTTATAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-62)

DNA recombination-mediator protein A (DNA_processg_A)

(73-269)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A1J0MYY1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Streptococcus mutans UA159	66.786	99.644	0.665
dprA/cilB/dalA	Streptococcus mitis SK321	57.5	99.644	0.573
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	57.143	99.644	0.569
dprA/cilB/dalA	Streptococcus pneumoniae D39	57.143	99.644	0.569
dprA/cilB/dalA	Streptococcus pneumoniae R6	57.143	99.644	0.569
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	57.143	99.644	0.569
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	56.786	99.644	0.566
dprA	Lactococcus lactis subsp. cremoris KW2	54.643	99.644	0.544

Detailed information NTG0829937