Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   QMA14_RS03675 Genome accession   NZ_CP125087
Coordinates   740988..742328 (+) Length   446 a.a.
NCBI ID   WP_065242968.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain EL1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 735988..747328
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMA14_RS03655 (QMA14_03655) - 738675..739523 (+) 849 WP_065242935.1 pilus assembly protein PilM -
  QMA14_RS03660 (QMA14_03660) - 739507..740022 (+) 516 WP_005694713.1 hypothetical protein -
  QMA14_RS03665 (QMA14_03665) - 740019..740561 (+) 543 WP_005694712.1 hypothetical protein -
  QMA14_RS03670 (QMA14_03670) - 740561..740944 (+) 384 WP_005697438.1 pilus assembly protein PilP -
  QMA14_RS03675 (QMA14_03675) comE 740988..742328 (+) 1341 WP_065242968.1 type IV pilus secretin PilQ Machinery gene
  QMA14_RS03680 (QMA14_03680) - 742348..743037 (+) 690 WP_065242967.1 ComF family protein -
  QMA14_RS03685 (QMA14_03685) nfuA 743153..743737 (+) 585 WP_005694707.1 Fe-S biogenesis protein NfuA -
  QMA14_RS03690 (QMA14_03690) comM 743781..745310 (-) 1530 WP_070712582.1 YifB family Mg chelatase-like AAA ATPase Machinery gene
  QMA14_RS03695 (QMA14_03695) yihA 745440..746054 (-) 615 WP_032822378.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  QMA14_RS03700 (QMA14_03700) - 746167..747036 (+) 870 WP_049371348.1 DUF535 family protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 49490.59 Da        Isoelectric Point: 6.1344

>NTDB_id=829894 QMA14_RS03675 WP_065242968.1 740988..742328(+) (comE) [Haemophilus parainfluenzae strain EL1]
MCFLILWTTYSVAENRVFSLRLKQAPIVETLQQLALEQNANLMIDDELEGTLSLQLDNVDFDRLLRSVAKIKGLSFYQEN
DIYYLGKPSQHEQYSEKITEPMAISGESLPSETPLVSTTVKLHFAKASDVMKSLTTGSGSLLSPSGTITFDDRSNVLLIQ
DDARSLKNIKKLIAELDKPIEQIVIEARIVTITDESLKELGVRWGIFNPTEAAHRVSGSLDANGFSNISNNLNVNFATTV
TPAGSLALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVTNGKNDTQSVEFREAVLGLEV
TPHISKDNNILLDLLVSQNSPGNRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKGVDKVPLLGDIPGIKR
LFSKESERHQKRELVIFVTPHILKQGERMEMAKKEKHFKQVEKAKK

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=829894 QMA14_RS03675 WP_065242968.1 740988..742328(+) (comE) [Haemophilus parainfluenzae strain EL1]
ATGTGTTTTCTGATCCTATGGACAACTTATTCAGTGGCAGAAAATCGCGTATTTTCACTTCGCTTAAAACAAGCTCCCAT
AGTAGAGACACTCCAACAACTTGCCCTTGAGCAAAATGCCAATTTAATGATTGATGATGAGTTAGAAGGAACACTTTCAT
TACAATTAGATAACGTAGATTTTGATCGTTTATTGCGTTCTGTCGCAAAAATCAAAGGGCTCTCTTTTTATCAAGAAAAT
GATATTTATTATTTAGGTAAGCCTTCTCAACATGAACAATATTCAGAGAAAATAACAGAACCTATGGCGATTAGCGGAGA
AAGTTTGCCTAGTGAAACACCACTTGTGAGTACAACGGTTAAACTGCATTTTGCTAAGGCTTCTGATGTGATGAAATCTT
TAACCACAGGGAGCGGTTCTTTGCTTTCACCTAGCGGCACAATTACATTTGATGATCGAAGCAATGTATTACTGATTCAG
GATGATGCACGTTCACTTAAAAATATCAAAAAATTAATTGCAGAGCTGGATAAACCTATTGAGCAAATTGTCATTGAAGC
ACGTATTGTGACGATTACCGATGAAAGCCTAAAAGAATTAGGTGTGCGTTGGGGCATTTTTAATCCTACTGAGGCAGCCC
ATCGAGTGAGTGGCAGTTTAGATGCGAATGGGTTTAGCAATATCAGTAATAATTTAAATGTAAATTTTGCGACAACGGTC
ACGCCAGCTGGCTCATTAGCACTTCAAGTAGCCAAAATTAATGGTCGATTATTAGACCTAGAATTGACCGCACTTGAACG
TGAAAATAACGTAGAAATTATAGCGAGTCCTCGCTTACTCACGACCAACAAAAAAAGCGCAAGCATCAAACAAGGGACAG
AAATTCCTTATGTGGTGACGAATGGTAAAAATGACACGCAGTCAGTGGAGTTTCGTGAAGCTGTGTTGGGGTTGGAAGTC
ACACCGCATATTTCGAAGGATAATAATATCTTATTGGATTTATTAGTCAGTCAAAACTCGCCAGGAAATCGCGTGGCTTA
TGGGCAGAATGAAGTCGTATCTATTGATAAACAAGAAATTAATACGCAAGTGTTTGCCAAAGATGGGGAAACGATTGTAT
TGGGCGGTGTATTTCACGATACGATCACGAAAGGTGTCGATAAAGTACCATTATTGGGCGATATTCCAGGTATTAAGCGC
TTATTTAGTAAGGAAAGTGAACGACATCAAAAACGAGAACTCGTAATTTTTGTGACTCCTCATATTTTGAAACAAGGTGA
AAGAATGGAAATGGCCAAAAAAGAAAAGCATTTTAAGCAAGTTGAAAAAGCGAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(264-424)

Bacterial type II/III secretion system short domain (Secretin_N)

(119-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

73.138

99.327

0.726
  comE Haemophilus influenzae 86-028NP

72.235

99.327

0.717
  comE Glaesserella parasuis strain SC1401

54.61

94.843

0.518
  pilQ Vibrio campbellii strain DS40M4

41.435

96.861

0.401
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

41.745

95.067

0.397
  pilQ Vibrio cholerae strain A1552

41.745

95.067

0.397