Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   H7679_RS09550 Genome accession   NZ_AP023392
Coordinates   1941071..1941793 (-) Length   240 a.a.
NCBI ID   WP_024385159.1    Uniprot ID   -
Organism   Streptococcus suis strain DAT300     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1936071..1946793
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7679_RS09530 (DAT300_18570) - 1936235..1937458 (-) 1224 WP_184495720.1 cysteine desulfurase -
  H7679_RS09535 (DAT300_18580) sufD 1937462..1938724 (-) 1263 WP_184495722.1 Fe-S cluster assembly protein SufD -
  H7679_RS09540 (DAT300_18590) sufC 1938741..1939514 (-) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  H7679_RS09545 (DAT300_18600) - 1939902..1941074 (-) 1173 WP_029751888.1 glycosyltransferase family 4 protein -
  H7679_RS09550 (DAT300_18610) mecA 1941071..1941793 (-) 723 WP_024385159.1 adaptor protein MecA Regulator
  H7679_RS09555 (DAT300_18620) - 1941921..1942757 (-) 837 WP_014638628.1 undecaprenyl-diphosphate phosphatase -
  H7679_RS09560 (DAT300_18630) - 1942884..1944449 (+) 1566 WP_024395367.1 ABC transporter substrate-binding protein/permease -
  H7679_RS09565 (DAT300_18640) - 1944442..1945185 (+) 744 WP_012775335.1 amino acid ABC transporter ATP-binding protein -
  H7679_RS09570 (DAT300_18650) - 1945313..1945522 (-) 210 WP_009910800.1 hypothetical protein -
  H7679_RS09575 (DAT300_18660) - 1945608..1946510 (-) 903 WP_002942264.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28017.56 Da        Isoelectric Point: 4.0497

>NTDB_id=82966 H7679_RS09550 WP_024385159.1 1941071..1941793(-) (mecA) [Streptococcus suis strain DAT300]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEETDEEEQERYIYYILEFPTIEDLFT
FIGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=82966 H7679_RS09550 WP_024385159.1 1941071..1941793(-) (mecA) [Streptococcus suis strain DAT300]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGTGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAGTCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGTGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAACAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTATTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTTTCAAGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.639

100

0.525
  mecA Streptococcus pneumoniae D39

51.639

100

0.525
  mecA Streptococcus pneumoniae R6

51.639

100

0.525
  mecA Streptococcus pneumoniae TIGR4

51.639

100

0.525
  mecA Streptococcus mutans UA159

50

100

0.508
  mecA Streptococcus thermophilus LMD-9

47.083

100

0.471
  mecA Streptococcus thermophilus LMG 18311

46.667

100

0.467

Multiple sequence alignment